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UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes.
Published 2013“…The histogram indicates the distribution of genes by average fold-change upon <i>unc-62</i> RNAi. For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”
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NCM treatment decreases hepatic CoQ<sub>10</sub>, but increases total cholesterol and cholesterol ester levels, which is associated with significant decreases in the expressions of...
Published 2014Subjects: “…mitochondrial ATP synthase subunit ATP 5A…”
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Fenretinide decreases levels of PAX3/FOXO1 and its target genes in aRMS cell lines.
Published 2013“…Representative values of at least two independent experiments. <i>Columns,</i> mean; <i>bars</i>, s.d. E) eRMS RD cells were treated during 24 hours with different concentrations of fenretinide (0.5–1–5 µM, as indicated). …”
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<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron.
Published 2013“…(B) Mouse spleen, 3 weeks post-infection; extramedullary hematopoiesis (EMH; arrow, megakaryocytes), histiocytic infiltration (I) throughout the red pulp, and thrombus (T). H&E stain (A, B). (C) Spleen, mock-infected (left) and infected mouse (right), 3 weeks post-infection; markedly decreased ferric iron staining in red pulp. …”
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Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation.
Published 2022“…Either Prb1 or Snf7 in <i>snf7Δ</i> cells facilitated GFP-Atg8 degradation and prApe1 maturation (bottom), but only Snf7 (not Prb1) facilitated phagophore closure in <i>snf7Δ</i> cells. The red arrows point to these key results. <b>F.</b> The blots shown in panel E were quantified as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010431#pgen.1010431.g006" target="_blank">Fig 6A and 6B</a>. …”
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Jurkat and HeLa survival decreases with increasing electric field amplitude and pulse number.
Published 2013“…For all exposures, Jurkat cells are more sensitive than HeLa cells. Data points represent the average survival. (mean +/−s.e., n = 3–5).…”
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POm E-stimulation before whisker stimulus does not decrease cortical response magnitude and duration when PTX is applied in L1.
Published 2016“…<p>(A) Percentage change in mean response magnitude by POm E-stimulation before (black) and after PTX application (grey). …”
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POm E-stimulation before whisker stimulus does not decrease cortical response magnitude and duration when AGA is applied in L1.
Published 2016“…<p>(A) Percentage change in mean response magnitude by POm E-stimulation before (black) and after AGA application (grey). …”
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Fold decrease in virulence gene expression of <i>Salmonella in vivo</i> and <i>in vitro</i><sup>a</sup>.
Published 2014“…Values represent down-regulation (fold-decrease) of gene expression.</p>#<p>Value for each gene represents a significant difference (<i>P</i><0.05) between the treatment and control samples in the <i>in vitro</i> experiment. …”
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A homozygous point mutation in the <i>Mrps34</i> gene causes a decrease in the MRPS34 protein.
Published 2015“…The 5′- and 3′-untranslated regions are shown as grey boxes and the predicted mitochondrial targeting sequence is shown as a black box (predicted using MitoProtII, [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005089#pgen.1005089.ref040" target="_blank">40</a>]). …”