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66981
Small-metabolite inhibitors of mGPDH are not selective.
Published 2014“…Data are means ± S.E. (n = 3). <i>GAP</i>, glyceraldehyde 3-phosphate; <i>Glu</i>, glutamate; <i>Mal</i>, malate; <i>Suc</i>, succinate; <i>Rot</i>, rotenone; <i>GP</i>, glycerol phosphate; <i>AtA5</i>, atpenin A5. …”
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66982
Group 10 Metal Dithiolene Bis(isonitrile) Complexes: Synthesis, Structures, Properties, and Reactivity
Published 2020“…Structurally, progressively greater planarity tends to be manifested as M varies from Ni to Pt, and a modest decrease in the CN bond length of coordinated CNR appears in moving from Ni toward Pt. …”
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66983
Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells
Published 2016“…The viabilities of 6 different cancer cell lines treated with a range of HMNE3 doses were detected using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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66984
The expression of pro-carcinogenic genes is modified already after 3 months of treatment.
Published 2014“…C) Mice treated with CDAA or CDAA+CCl<sub>4</sub> show, starting at 3 months, increased levels of mRNA for IGF-2 and (D) SPP-1 and (E) decreased mRNA levels of PTEN. Data represent mean ± SD; *p<0.05 vs CSAA; #p<0.05 vs CSAA+CCl<sub>4</sub>.…”
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66985
Evaluation of retinal and choroidal microvascular changes in patients who received hydroxychloroquine by optical coherence tomography angiography
Published 2021“…The macular flow area (superficial, deep, and choriocapillaris), superficial and deep vessel density, foveal avascular zone area, central foveal thickness, and subfoveal choroidal thickness parameters were measured by optical coherence tomography angiography. Results: The mean age of the 28 patients who received hydroxychloroquine and the 28 age-matched controls was 45.5 ± 11.1 years (range: 29-70 years) and 44.5 ± 13.9 years (range: 28-70 years), respectively. …”
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66986
Table_1_Ten-Eleven Translocation (TET) Enzymes Modulate the Activation of Dendritic Cells in Allergic Rhinitis.DOCX
Published 2019“…</p><p>Methods: The levels of TETs in peripheral blood mononuclear cells (PBMCs), peripheral myeloid DCs (mDCs), and plasmacytoid DCs (pDCs) from house dust mite (HDM)-sensitive AR patients and healthy volunteers (HC) were evaluated by qPCR and flow cytometry. The levels of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) in PBMCs were determined by DNA-5hmC and DNA-5mC ELISA. …”
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66987
The effect of salts, pH and additives in the lysis buffer on the solubility of RGP1.
Published 2017“…Buffers 13 and 19–21, containing 1-2M salt, as well as the low-pH (4.3–5.5) buffers 11,12,15, 22 and 30 decrease the amount of soluble RGP1, while lower salt concentrations as well as several additives increase the amount of soluble RGP1 relative to the standard lysis buffer (std: 50 mM HEPES pH 8.0, 250 mM NaCl, 5 mM MgCl<sub>2</sub>). …”
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66988
Grid division diagram.
Published 2025“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”
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66989
Model calculation diagram.
Published 2025“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”
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66990
Grid independence verification.
Published 2025“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”
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66991
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66992
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66993
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66994
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66995
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66996
Table_2_Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy.XLSX
Published 2021“…Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. …”
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66997
Secondary screening and ‘hit’ validation.
Published 2016“…Treatment with 1.2 μM of SAHA resulted in a ~ 40% decrease in NDST enzyme activity. Experiments were conducted in triplicates. …”
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66998
Table_1_Association of Metabolic Syndrome With Prevalence of Obstructive Sleep Apnea and Remission After Sleeve Gastrectomy.XLSX
Published 2021“…Then we performed a retrospective study, which was registered at ClinicalTrials.gov (ref. …”
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66999
Computational Investigation of the Lewis Acidity in Three-Dimensional and Corresponding Two-Dimensional Zeolites: UTL vs IPC-1P
Published 2014“…The adsorption and catalytic properties of three-dimensional zeolite UTL were investigated computationally along with properties of its two-dimensional analogue IPC-1P that can be obtained from UTL by a removal of D4R units. Adsorption properties and Lewis acidity of extra-framework Li<sup>+</sup> sites were investigated for both two- and three-dimensional forms of UTL using the carbon monoxide as a probe molecule. …”
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67000
DataSheet1.pdf
Published 2018“…Using computer simulations employing a multicellular in silico model, we furthermore demonstrate that the experimentally observed increase in K<sub>V</sub>4.3 current and concurrent decrease in Na<sub>V</sub>1.5 current may result in a loss of conduction, underlining the potential functional relevance of our findings. …”