Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Fenugreek exposure decreased the frequency and the alternations of the locomotor like activity. by Loubna Khalki (480082)

Percentage of biomass that decreased in relation to the control after the incubation period (5 days) of the experimental cultures containing 100 ml of each of the three different <... by Fabiana Araújo (5052323)

PowerPoint Slides for: Clinical Trial of Vadadustat in Patients with Anemia Secondary to Stage 3 or 4 Chronic Kidney Disease by Martin E.R. (3859435)

“…<b><i>Methods:</i></b> A phase 2a, multicenter, randomized, double-blind, placebo-controlled, dose-ranging trial (NCT01381094) was undertaken in adults with anemia secondary to CKD stage 3 or 4. …”

Forest plots illustrate the mean difference in; (A) hospital stay, (B) ICU stay, (C) intubation time; with subgroup analysis. by Mohamed R. Abdelraouf (21501468)

Treatment with DHA and DHA/HTF decreased Jurkat cell viability. by Qiuyan Wang (237527)

Decrease in ATP and AMPK activation in sensitive and resistant cell lines. by Alper Y. Kearney (789031)

Decreased granuloma size in PPD-challenged CLP RAG lungs. by William F. Carson IV (197974)

Inhibition of TGF-β decreases endothelial barrier function in vivo. by Tony E. Walshe (269700)

“…Scale = 0.5 µm. (D) Immunoprecipitation of occludin and western blotting for zo-1 demonstrated a significant decrease in association between occludin and zo-1 in lysates prepared from retinas of sEng-expressing mice (day 7). …”

Overexpression of Rheb in the mushroom bodies decreases memory for sucrose reward. by Heather L. D. Brown (306759)

Potentiodynamic polarization curves for P110 carbon steel corrosion in the absence and presence of different concentrations of (a) 5, (b) 6a and (c) 6b. by Ghadeer Mubarak (21567569)

Paired-pulse depression decreases between birth and hearing onset. by Daniel T. Case (350039)

LY5 treatment did not inhibit RMS or OS xenograft tumor growth. by Peter Y. Yu (4281448)

Exogenous activation of BMP signaling decreases apoptosis in POb cells. by Shuli Li (24534)

“…BMP-2 treatment decreases apoptosis markedly in POb cells compared to untreated POb, a lower apoptotic activity is also observed in BMP-2 treated FOb as compared to untreated FOb cells. …”

ATXN3 depletion decreases PNKP’s 3’-phosphatase activity. by Arpita Chatterjee (529752)

Waterborne Tebuconazole Exposure Induces Male-Biased Sex Differentiation in Zebrafish (Danio rerio) Larvae via Aromatase Inhibition by Kun Qiao (6017606)

Subjects:

Waterborne Tebuconazole Exposure Induces Male-Biased Sex Differentiation in Zebrafish (Danio rerio) Larvae via Aromatase Inhibition by Kun Qiao (6017606)

Subjects:

Waterborne Tebuconazole Exposure Induces Male-Biased Sex Differentiation in Zebrafish (Danio rerio) Larvae via Aromatase Inhibition by Kun Qiao (6017606)

Subjects:

Waterborne Tebuconazole Exposure Induces Male-Biased Sex Differentiation in Zebrafish (Danio rerio) Larvae via Aromatase Inhibition by Kun Qiao (6017606)

Subjects: