Reduction of SIRT1 during DNA damage decreases the number of silent clones that have methylation. by Heather M. O'Hagan (271283)

“…One representative bisulfite sequenced clone is presented for each HSVTK silent clone. (B) A dot plot of the mean number of CpGs methylated per HSVTK silenced clone from either un-siRNA treated cells (untreated) (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000155#pgen-1000155-g005" target="_blank">Figure 5D & E</a>), non-target siRNA treated cells (NT), or SIRT1 siRNA treated cells (SIRT1). …”

CR increases ROS and decreases the mtDNA copy number in MLH1 deficient cells. by Berna Somuncu (12770334)

Decreased expression of proteins involved in mitochondrial dynamics and regulation of oxidative stress in prion infected mice. by Anne Ward (334296)

Loss of ASAP1 results in decreased numbers of neonatal subcutaneous adipocytes and reduced body weight. by Caroline Schreiber (383327)

Decreased survival, splenomegaly, thrombocytopenia and megakaryocyte alterations in SCID-Rasa3^−/− mice. by Patricia Molina-Ortiz (167505)

Point cell model behavior. by Evan Cudone (5768813)

AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. by Anthony L. Gaeta (13272609)

ATRA decreases the binding of Nrf2 to ARE sequences in the promoter regions of HO-1, GCLM and x-CT in BTZ-treated cells. by A. L. Furfaro (2587792)

Inhibition of <i>miR-750</i> led to decreased egg production in female schistosomes. by Pengfei Du (513926)

“…<p>A) RT-qPCR analysis of <i>miR-750</i> expression in female and male schistosomes. ns means no statistically significant difference. …”

LAP whole blood displays Increased capacity for 5-HETE and LTB₄ levels, and decreased for 12-HETE, 14-HDHA, 15-HETE and LXA₄. by Gabrielle Fredman (272178)

DR extends lifespan, increases stress resistance and decreases fecundity in <i>C. elegans</i>. by Di Chen (15424)

Positive modulation of mGluR5 decreases spine density in the nucleus accumbens but not in the dorsal striatum. by Kellie S. Gross (3115299)

“…<p>(A) Twenty-four hours after systemic administration, CDPPB (5–10 mg/kg, <i>n</i> = 18 animals) decreased dendritic spine density and frequency of small head diameter spines (0.2 μm bin) compared to vehicle control (<i>n</i> = 8) in the nucleus accumbens core. …”

Islet apoptosis increases in HFD-PBS and HFD-MSCs-NR and decreases in HFD-MSCs-R. by Patricia de Godoy Bueno (731717)

KPn infection decreases the level of surface exposed phosphatidylserine (PS) and reduces efferocytosis of infected neutrophils. by Christopher N. Jondle (5807657)

Loss of <i>Rab23</i> decreases ciliation in MEFs and Tbr1 + intermediate progenitors. by Wan Ying Leong (22075947)

REH2 knockdown decreased substrate loading and increased pausing during editing in 3010-MRB. by Bhaskara R. Madina (732552)

Knockdown of GLUT1 decreases de uptake and phototoxicity of PcGal₁₆. by Patrícia M. R. Pereira (555179)

Knockdown of galectin-1 decreases de uptake and phototoxicity of PcGal₁₆. by Patrícia M. R. Pereira (555179)

Que treatment decreases the number of T cells in the spleen and lymph nodes and inhibites proliferation of effector T cells. by Feng Mei (143817)

“…Data represent mean ± SEM of five independent experiments (N = 5, <i>*, p<</i>0.05).…”

The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>. by Yuehui Zhao (3146229)

“…Cyan: p<0.01, log₂(Fold Change) < -1. (The list of differential expressed genes with significance are available in <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008606#pgen.1008606.s018" target="_blank">S5 Table</a></b>). …”