VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

ArxE mice have almost complete loss of α-cell fate by P14 with a concomitant decrease in total endocrine mass, but no change in β- and δ-cell mass. by Crystal L. Wilcox (421799)

Retinoic acid alleviates decrease of phospho-Bad and 14-3-3 interaction caused by MCAO damage. by Ju-Bin Kang (16021324)

“…Molecular weights (kDa) are depicted at right. Data (<i>n</i> = 5) are represented as mean ± S.E.M. *<i>p</i> < 0.001, **<i>p</i> < 0.01, ***<i>p</i> < 0.05 vs. vehicle + sham animals, #<i>p</i> < 0.01, ##<i>p</i> < 0.05 vs. vehicle + MCAO animals.…”

Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction – implications for treating preeclampsia by Tu’uhevaha J. Kaitu’u-Lino (317587)

Table_1_Educational Attainment Decreases the Risk of COVID-19 Severity in the European Population: A Two-Sample Mendelian Randomization Study.XLSX by Masahiro Yoshikawa (379956)

Image_2_Educational Attainment Decreases the Risk of COVID-19 Severity in the European Population: A Two-Sample Mendelian Randomization Study.TIF by Masahiro Yoshikawa (379956)

Image_3_Educational Attainment Decreases the Risk of COVID-19 Severity in the European Population: A Two-Sample Mendelian Randomization Study.TIF by Masahiro Yoshikawa (379956)

Image_1_Educational Attainment Decreases the Risk of COVID-19 Severity in the European Population: A Two-Sample Mendelian Randomization Study.TIF by Masahiro Yoshikawa (379956)

POS treatment decreases ROS level and upregulates mitochondrial biogenesis in ARPE-19 cells through PGC-1α. by Murilo F. Roggia (755997)

“…<b>(E)</b> POS treatment upregulated relative mitochondrial DNA content. …”

Low oscillatory shar stress <i>Arf6</i> heterozygosity decreases Arf6 expression. by Venkateswara R. Gogulamudi (15447428)

Photostimulation of DRN 5-HT neurons <i>in vivo</i>. by Guillaume P. Dugué (620333)

(+)-Usnic acid decreases mRNA level of downstream target genes of β-catenin/LEF and c-jun/AP-1. by Yi Yang (116183)

Selective downregulation of SR Ca²⁺ handling proteins and decreased SR Ca²⁺ uptake in TG mice hearts. by Mayilvahanan Shanmugam (691549)

“…For each atrial Ca²⁺ uptake experiment, atria from four mice were pooled. n = 4 for each group. The V_max of Ca²⁺ uptake was obtained at pCa 5.5.…”

RTA 408 Increases Expression of Nrf2 Target Genes and Decreases Expression of Inflammatory Mediators in RAW 264.7 Cells. by Brandon L. Probst (727964)

Participants characteristics. by Sakiko Fukui (387048)

“…</p><p>Methods</p><p>Sixty-nine deceased older adults from five special nursing homes were studied over 3.5 years (January 2016 to June 2020). …”

Data_Sheet_5_Artesunate Alleviates Paclitaxel-Induced Neuropathic Pain in Mice by Decreasing Metabotropic Glutamate Receptor 5 Activity and Neuroinflammation in Primary Sensory Neu... by Yize Li (471459)

“…We demonstrated artesunate prevented PINP in a dose-dependent manner, while exerting a clear anti-hyperalgesic effect on already existing PINP. …”

Age-stage-specific reproductive values (<i>v</i>_<i>xj</i>) of <i>A</i>. <i>glycines</i>. by Aonan Zhang (8933630)

Age-stage-specific reproductive values (<i>v</i>_<i>xj</i>) of <i>A</i>. <i>glycines</i>. by Aonan Zhang (8933630)

Decreased consumption of methionine sulfoxide (MetO) by the <i>V</i>. <i>cholerae</i> Δ<i>gcvT</i> mutant attenuates virulence by promoting intestinal lipid mobilization and insuli... by Audrey S. Vanhove (4090594)

Advanced glycation end-products (AGEs) increased the expressions of RAGE, p38 MAPK, and Bax and decreased the Bcl-2 expression. by Kuo-Cheng Lan (727846)