Screening TAS2R5 agonists for the receptor downregulation response to long- term agonist exposure. by Donghwa Kim (252081)

“…<p>HEK-293T cells stably expressing FLAG-tagged TAS2R5 were exposed in culture for 18 hrs to the indicated agonists at a concentration 10-fold greater than their functional EC₅₀ values. …”

Influence of Thiolate Ligands on Reductive N−O Bond Activation. Probing the O₂⁻ Binding Site of a Biomimetic Superoxide Reductase Analogue and Examining the P... by Gloria Villar-Acevedo (2232583)

“…Like NO-bound <i>trans</i>-cysteinate-ligated SOR (SOR-NO), the rhombic <i>S</i> = 3/2 EPR signal of NO-bound <i>cis</i>-thiolate-ligated [Fe(S^Me₂N₄(tren)(NO)]⁺ (<b>2</b>; <i>g</i> = 4.44, 3.54, 1.97), the isotopically sensitive ν_NO(ν_¹⁵NO) stretching frequency (1685(1640) cm⁻¹), and the 0.05 Å decrease in Fe−S bond length are shown to be consistent with <i>the oxidative addition of NO to Fe(II)</i> to afford an Fe(III)−NO⁻ {FeNO}⁷ species containing high-spin (<i>S</i> = 5/2) Fe(III) antiferromagnetically coupled to NO⁻ (<i>S</i> = 1). …”

Influence of Thiolate Ligands on Reductive N−O Bond Activation. Probing the O₂⁻ Binding Site of a Biomimetic Superoxide Reductase Analogue and Examining the P... by Gloria Villar-Acevedo (2232583)

“…Like NO-bound <i>trans</i>-cysteinate-ligated SOR (SOR-NO), the rhombic <i>S</i> = 3/2 EPR signal of NO-bound <i>cis</i>-thiolate-ligated [Fe(S^Me₂N₄(tren)(NO)]⁺ (<b>2</b>; <i>g</i> = 4.44, 3.54, 1.97), the isotopically sensitive ν_NO(ν_¹⁵NO) stretching frequency (1685(1640) cm⁻¹), and the 0.05 Å decrease in Fe−S bond length are shown to be consistent with <i>the oxidative addition of NO to Fe(II)</i> to afford an Fe(III)−NO⁻ {FeNO}⁷ species containing high-spin (<i>S</i> = 5/2) Fe(III) antiferromagnetically coupled to NO⁻ (<i>S</i> = 1). …”

Table_5_Comprehensive proteome, phosphoproteome and kinome characterization of luminal A breast cancer.xlsx by Ganglong Yang (778465)

“…</p>Results<p>In the luminal A breast cancer, a total of 5,044 high-confidence proteins and 3,808 phosphoproteins were identified from 10 paired tissues. …”

MeV induced RIG-I pathway <i>via</i> RNA polymerase III. by Pierre Khalfi (7868252)

Table_5_Primary Metabolite Adjustments Associated With Pinewood Nematode Resistance in Pinus pinaster.XLSX by Ana M. Rodrigues (8630319)

Table_5_Primary Metabolite Adjustments Associated With Pinewood Nematode Resistance in Pinus pinaster.XLSX by Ana M. Rodrigues (8630319)

Perturbation of NOTCH, PRMT5 or YY1 does not affect mycobacterial uptake in macrophages. by Salik Miskat Borbora (9381455)

Datasets with one replicate per time-point over a unique cycle of 24 hours do not provide enough information to detect rhythmicity. by David Laloum (8587443)

“…<p>Methods lose in statistical power for detecting rhythmic patterns in gene expression when the number of 24h cycles decreases, or when the number of time-points sampled decreases. …”

PRMT5 activity aids in the sustained accumulation of lipid droplets during Mtb infection. by Salik Miskat Borbora (9381455)

3D representation of MeV infected cells realized with IMARIS 9.9.1. by Pierre Khalfi (7868252)

A Five-Species Transcriptome Array for Oral Mixed-Biofilm Studies by Sylvio Redanz (192814)

“…Employing a stringent cut-off (2-fold, p<0.05), 19 <em>S. mutans</em> transcripts were identified with increased abundance, and 11 with decreased abundance compared to a <em>S. mutans</em> mono-species biofilm. …”

Graphic representation of the SARS-CoV-2 testing outcome of 10,014 nasopharyngeal swabs. by William R. Webb (13046882)

Image_5_Future-Proofing Potato for Drought and Heat Tolerance by Overexpression of Hexokinase and SP6A.png by Günter G. Lehretz (9972338)

Table5_Trichostatin A relieves anxiety-and depression-like symptoms in APP/PS1 mice.XLSX by Qiang Su (1611796)

Moving Pieces in a Cellular Puzzle: A Cryptic Peptide from the Scorpion Toxin Ts14 Activates AKT and ERK Signaling and Decreases Cardiac Myocyte Contractility via Dephosphorylation... by Diana P. Goméz-Mendoza (9104908)

Moving Pieces in a Cellular Puzzle: A Cryptic Peptide from the Scorpion Toxin Ts14 Activates AKT and ERK Signaling and Decreases Cardiac Myocyte Contractility via Dephosphorylation... by Diana P. Goméz-Mendoza (9104908)

Deletion of murine <i>Rhoh</i> leads to de-repression of <i>Bcl-6</i> via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma by Hiroto Horiguchi (3215001)

“…RHOH was initially identified as a translocation partner with BCL-6 in non-Hodgkin lymphoma (NHL), and aberrant somatic hypermutation (SHM) in the 5ʹ untranslated region of the RHOH gene has also been detected in Diffuse Large B-Cell Lymphoma (DLBCL). …”

Data used in analysis. by Rong Tang (130779)

Subjects:

QoR-15 scores after surgery. by Rong Tang (130779)

Subjects: