Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy by Yong-Chul Kim (1637572)

“…We randomly assigned patients either to receive tacrolimus or placebo with stratification by using a renin angiotensin system blocker. …”

Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

“…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC₅₀’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …”

Table S1 - Human <i>NR5A1</i>/SF-1 Mutations Show Decreased Activity on BDNF (Brain-Derived Neurotrophic Factor), an Important Regulator of Energy Balance: Testing Impact of Novel SF-1 Mutations Beyond Steroidogenesis by Jana Malikova (615672)

Subjects:

Decrease of viral load and ALT at different time points under treatment according to NS5A-inhibitors and interferon administration. by Valeria Cento (103603)

GREAT GO analysis of WDR5 and MYCN overlapped ChIP-seq peaks with >2.5-fold decrease of WDR5 signal intensity after the silencing of <i>WDR5</i>. by Zhihui Liu (95891)

A Yoga Strengthening Program Designed to Minimize the Knee Adduction Moment for Women with Knee Osteoarthritis: A Proof-Of-Principle Cohort Study by Elora C. Brenneman (795723)

“…A secondary objective was to determine whether the program could improve mobility and fitness, and decrease peak KAM during gait. …”

A DNA-PKcs-specific inhibitor decreases HBoV1 infection of HAE-ALI. by Xuefeng Deng (138723)

Taurolidine lock solution for catheter-related bloodstream infections in pediatric patients: A meta-analysis by Yan Sun (22436)

“…The number of catheters removed due to infection or suspected infection was not significantly different between the two groups (RR: 0.68; 95% CI:0.22, 2.10; I² = 56%; P = 0.50) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0231110#pone.0231110.g005" target="_blank">Fig 5</a>). …”

CypB KO mice exhibit differential gene expression compared to WT mice undergoing a NAFLD/NASH model. by Winston T. Stauffer (18086483)

“…RNA isolated from the 8 WT livers and 5 CypB KO livers were analyzed in PCR arrays for genes relevant to hepatotoxicity or liver fibrosis. …”

Shortening of mTL anticipates accumulation of DDR markers, decrease in cell proliferation and increase in apoptotis with age. by Madalena C. Carneiro (102302)

“…All tissues show a significant increase in cells bearing five or more γH2AX foci by 12 months of age in <i>tert</i>^-/- zebrafish (panels b, d) and by 36 months in WT zebrafish (panels a, c and e). …”

The amount of 3’UTR-derived piRNAs does not decrease in follicle cells lacking Drosha activity. by Bruno Mugat (741210)

Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice by Ryosuke Tateishi (135017)

Identification of a Novel C-Terminal Truncated WT1 Isoform with Antagonistic Effects against Major WT1 Isoforms by Naoya Tatsumi (757579)

“…Ex4a(+)WT1 isoform was endogenously expressed as a minor isoform in myeloid leukemia and solid tumor cells and increased regardless of decrease in major WT1 isoforms during apoptosis, suggesting the dominant negative effects on anti-apoptotic function of major WT1 isoforms. …”

Plasmid and genomic changes detected in de-evolution trials. by Irina V. Bakhlanova (2636080)

Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation by Elias Gounaris (52393)

“…Here we report that Zileuton, a specific 5-LO inhibitor, can prevent polyp formation by efficiently reducing the tumor-associated and systemic inflammation in APC^Δ468 mice.…”

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)

Cre-mediated activation of RIαB allele specifically in the liver decreases PKA activity in vivo. by Brandon S. Willis (353418)

Decreased proliferation in tuft endothelium despite increased VEGFA level in N-CAM deficient retinas in OIR. by Joakim Håkansson (200855)

“…(A, B) Decrease in endothelial cell proliferation in N-CAM deficient retinas (B) compared to wt (A) was restricted to the tufts, whereas the remaining vasculature was unaffected (arrowheads indicate veins). …”

C/EBPε-deficient mice have decreased PMNs but develop equivalent hypoxemia and edema with VILI. by Heather D. Jones (476855)

Supplementary Material for: TNFAIP2 Inhibits Early TNFa-Induced NF-κB Signaling and Decreases Survival in Septic Shock Patients by Thair S.A. (4152325)