The novel <i>carboxylesterase 1</i> variant c.662A>G may decrease the bioactivation of oseltamivir in humans by Jaeseong Oh (3947381)

“…A novel <i>CES1</i> c.662A>G single nucleotide polymorphism (SNP) was predicted to decrease CES1 enzymatic activity in an <i>in silico</i> analysis. …”

In vivo targeting of miR-155-5p with an antagomir effectively decreases expression but has no impact on disease. by Maximilian W. Plank (839968)

Time course of central retinal thickness (CRT) in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…These values significantly decreased in the first postoperative year to 2.3 ± 2.6, 0.1 ± 0.3, 0.8 ± 1.6, 0, and 3.1 ± 2.8; in the second year to 2.1 ± 2.8, 0.4 ± 1.0, 0.0, 0.1 ± 0.3, and 2.6 ± 2.8; and in the third year to 2.0 ± 2.2, 0, 0.6 ± 1.7, 0.1 ± 0.3, and 2.8 ± 3.5 (Kruskal–Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g007" target="_blank">Fig 7</a>). …”

GSPs decrease cell viability and induce cell death of HNSCC cells. by Ram Prasad (305524)

Syndecan ectodomain fragments decrease endothelial resistance via rho kinase. by Melanie Jannaway (6703577)

“…(C) rhS4ED fragments significantly decreased TER (n = 8, p = 0.0002). (D) Fragments of non-glycosylated form of rhS4ED also generated significant decreases in TER (n = 5, p = 0.0011). …”

Administration of BL-7010 (Polymers A and B) at a gluten: BL-7010 ratio of 1∶3 decreased gluten-associated histological pathology in the small intestine of sensitized mice. by Justin L. McCarville (432593)

Decreased BIRC6 expression induces apoptosis and inhibits autophagosome formation. by Christopher G. Low (280918)

“…<p><b>A</b>, apoptosis of LNCap cells transfected with Lipofectamine (Lipo), non-targeting control siRNA (NT) or <i>BIRC6</i> siRNA2 and subsequently incubated for 48 h, as assessed by flow cytometric analysis of Annexin V/PI stained cells. …”

ΔNp73α mRNA levels are high in the skin of HPV38 E6/E7 Tg mice, but are decreased in the UV-induced skin lesions harbouring p53 mutations. by Daniele Viarisio (348197)

Proliferation marker Ki-67 is decreased by rLOX-PP treatment. by Manish V. Bais (333481)

Decreased Rab10 localization in raft fractions following methamphetamine treatment. by Scott M. Vanderwerf (785324)

Decreases in white matter integrity in t(1;11) translocation carriers (n = 7) versus non-carriers (n = 13) and in patients (n = 34) versus controls (n = 33). by Heather C. Whalley (287657)

“…To aid visualization the results (pfwe < 0.05) are thickened using the “tbss-fill” command. Statistics for FA decreases in the patient group versus controls for these peaks; cluster 1: p = 0.023 at [-3, 28, 6; left genu of corpus callosum], cluster 2: p = 0.032 at [29, 26, 15; right fronto-occipital fasciculus], cluster 3: p = 0.012 at [11, 26, 14; right genu of corpus callosum], cluster 4: p = 0.033 at [20, 25, 0; right acoustic radiation], and cluster 5: p = 0.031 at [28, -24, -8; right fornix] i.e. for clusters 1–5 respectively, see, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0130900#pone.0130900.t002" target="_blank">Table 2</a>).…”

MET knockdown decreases EGFR activation and does not influence EGFR expression. by Karolin Ebert (7434713)

Time course of best-corrected visual acuity (BCVA) in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…In the non-recurrence group, CRT improved from 482.5 ± 112.8 to 294.7 ± 65.3, 302.0 ± 68.0, 284.7 ± 55.4, 285.3 ± 70.2, 265.2 ± 65.0, and 266.1 ± 78.2 μm at 1, 3, 6, 12, 24, and 36 months, respectively (Kruskal-Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g006" target="_blank">Fig 6</a>).…”

Influenza virus infection decreases CLEC7A (Dectin1) mRNA and reduces phagocytosis of zymosan by AM. by Jieru Wang (179734)

“…<p>Panel A. Human AM were cultured and infected by PR/8 at a MOI of 0.5. …”

Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<b>a. RT-qPCR analysis:</b> relative TMPRSS2-ERG fusion variants III and IV mRNA levels were analysed and compared to non-treated cells. …”

Oral UOX decreased SUA (A), BUN (B) and Cr (C) (mean ± SD, n = 10). by Yu Yun (4710340)

Telmisartan decreased NO production in LPS-stimulated BV2 and primary neonatal rat glial cells. by Nofar Torika (3169497)

Decreased <i>Leishmania</i> species infection and increased leishmanicidal molecules after IL-32 overexpression in human THP-1-derived macrophages. by Jéssica Cristina dos Santos (600716)

Wnt5a expressing tumors demonstrate a decrease in markers of the basal tumor subtype. by Stephanie L. Easter (662168)

“…MMTV-Wnt1;MMTV-Wnt5a tumors demonstrated a significant decrease in K6-expressing cells as measured by T-test (* = p<0.05).…”

Over expression of hnRNP A1 decreases and hnRNP F increases inclusion of exon 11 of an <i>INSR</i> minigene, whereas knockdown of endogenous hnRNP F and hnRNP A1 has the opposite e... by Indrani Talukdar (195204)