Relish SUMOylation decreases its transcriptional activity. by Ruijuan Tang (11250680)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Knocking down <i>ETH</i> arrests ovarian development and decreases JH signaling under SD condition. by Shuang Guo (294074)

Stable isotope biplots of end-members (colored points) faceted by coastscape and overlayed consumers (gray points). by Nathan D. McTigue (10706460)

Pancreatic cancer cell proliferation is decreased upon M344 treatment. by Shelby M. Knoche (13833807)

Decrease of autoantibody levels in highly inflammatory NSG mice. by Henrika Jodeleit (4722312)

Biocompatible and Antifouling Linear Poly(<i>N</i>‑(2-hydroxypropyl)methacrylamide)-Coated Capillaries via Aqueous RAFT Polymerization Method for Clinical Proteomics Analysis of No... by Mengqing Yang (13253917)

Changes in NT-proBNP, LVEF, E/e’ (FAS), and TRPG (PPS) in each HFrEF and HFpEF patients. by Masashi Sakuma (3923087)

E2 induces increased chromosome conformation capture contact frequencies but decreased proximity between enhancers and promoters. by Luciana I. Gómez Acuña (18605719)

HRV parameters at different time points. by Shiying Liu (1569478)

Patient demographic information at four time points. by Ruitian Song (11045127)

Color data collection points on the body of ornamental shrimp. by Wei-Wei Hou (3405947)

Numerical data points underlying presented graphs. by Luke R. Joyce (12107297)

Metabolite concentrations decrease to near-uninfected levels after treatment of infection. by Derick N. M. Osakunor (4839597)

Yta4 decreases the affinity of Dnm1 for GTP. by Jiajia He (795335)

Depletion of putative SDH subunits leads to decreased SDH activity and oxygen consumption. by Mariana F. Silva (10219520)

Data_Sheet_1_Marathon Running Increases Synthesis and Decreases Catabolism of Joint Cartilage Type II Collagen Accompanied by High-Energy Demands and an Inflamatory Reaction.PDF by José A. Hernández-Hermoso (11545663)

“…Mean sC2C levels (220.83 ± 39.50 ng/ml) decreased post-race (188.67 ± 38.52 ng/ml) (p = 0.002). …”

Assessment of cell proliferation within the vocal fold muscle following DFATs transplantation. by Ikuo Mikoshiba (9312007)

The shortened version of the Edinburgh Handedness Inventory encompasses 4 items (e.g. writing) scored on a 5-point scale ranging from:” Always right; usually right; both equally; u... by Marcel F. Hinss (14675457)