Blockade of mTORC2 decreased TRPC6-dependent calcium influx in podocytes (confocal microscopy). by Fangrui Ding (659863)

“…The podocytes in rows 1, 2, and 3 were exposed to DMSO (control conditions), rapamycin (50 nmol/l) and ku0063794 (3 µmol/l) for 24 h, respectively. (B, E) The images in rows 1, 2, and 3 are magnifications of cells 1, 2, and 3 marked in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0112972#pone-0112972-g004" target="_blank">Figure 4A</a>, respectively, depicting the changes in fluorescence over shorter periods. …”

<i>Becn1</i>^F121A leads to autophagy hyperactivation in vivo. by Altea Rocchi (3278457)

Down-regulation of Bim in EBV-positive cells is not due to proteosomal degradation or decreased mRNA stability. by Kostas Paschos (262658)

<i>Becn1</i>^FA/FA mutation ameliorates cerebral Aβ accumulation, memory deficits and mortality of Alzheimer’s mouse models. by Altea Rocchi (3278457)

Decreased CD14⁺ MDSCs in bone marrow were associated with increased immune activation. by Yongjun Sui (829771)

Loss of <i>Igfbp7</i> decreases the alveolar density of the mammary gland during the pregnancy and lactation. by Sumanta Chatterjee (519822)

“…As demonstrated, loss of <i>Igfbp7</i> leads to marked decrease in the alveolar densities in the mammary glands at each of the developmental time points studied. …”

Decreased CD39 protein expression by islet resident macrophages heralds T1D in NOD mice. by Thomas B. Thornley (2550766)

Decreasing immunogenicity of clade B HIV-1 variants in term of NAbs induction over the course of the epidemic. by Mélanie Bouvin-Pley (430423)

GRIP1^-/- platelets do not have decreased velocity in ionophore-stimulated blood vessels. by Kristina L. Modjeski (3123072)

“…C) GRIP1^-/- platelets do not have decreased velocity in an ionophore-stimulated mesenteric vessel (N = 4 ± S.E.M; *P < 0.05 by students T-test GRIP1^-/- vs WT). …”

Epithelial AQP1 expression is decreased following treatment of CMT93 epithelial cells with IFNγ. by Michael S. Dicay (707490)

“…<p>Confocal immunocytochemistry was performed to detect AQP1 in CMT93 cells treated with either vehicle or IFNγ (10 ng/mL for 24 hr). Constitutive AQP1 immunoreactivity was observed apically and laterally in control cells, which co-localized with E-cadherin. …”

Data_Sheet_1_SLC38A10 Knockout Mice Display a Decreased Body Weight and an Increased Risk-Taking Behavior in the Open Field Test.pdf by Frida A. Lindberg (8082476)

The decrease in 2774 ovarian cancer cell migration and invasion as a result of Tβ₁₀ overexpression. by Young-Chae Kim (163381)

SARS-CoV-2 inhibits SG formation and decreases expression of G3BP1. by Stacia M. Dolliver (13822801)

TPI demalonylation at K56 decreases PPP flux in CDCP1+ CSCs and is indispensable for postchemotherapeutic recurrence. by WenChao Gao (7321640)

Proteomic identification of substrates for seven-beta-strand MTases. by Tadahiro Shimazu (619411)

Subjects:

Selenium-Based <i>S</i>-Adenosylmethionine Analog Reveals the Mammalian Seven-Beta-Strand Methyltransferase METTL10 to Be an EF1A1 Lysine Methyltransferase by Tadahiro Shimazu (619411)

Subjects:

ProSeAM, a synthetic SAM analog, has a wide spectrum of reactivity for histones and non-histone substrates. by Tadahiro Shimazu (619411)

Subjects:

METTL10 knockdown reduces the level of lysine 318 methylation in EF1A1 <i>in vivo</i>. by Tadahiro Shimazu (619411)

Subjects:

Laminar flow increases the expression of anti-oxidant genes and decreases the inflammatory basal state of GEnC. by Daan C. ‘t Hart (10751645)

TGF-β₁ decreased soluble FBLN-1 from human ASM cells. by Ling Chen (25698)