Hypermutability of <i>Mycolicibacterium smegmatis</i> due to ribonucleotide reductase-mediated oxidative homeostasis and imbalanced dNTP pools by Xiao Zhang (152326)

“…Here, we constructed inducible knockdown strains for the RNR R1 subunit NrdE in Mtb and Mycolicibacterium smegmatis (Msm). …”

Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for <i>Toxoplasma gondii</i> Proliferation by Jiachen Wang (505061)

“…To further explore the function of GCN5b, we generated clonal parasites expressing an inducible HA-tagged dominant-negative form of GCN5b containing a point mutation that ablates enzymatic activity (E703G). …”

Effects of PACAPs and/or oxidative stress on NFAT4, calcineurin expression and activity in chondrifying cells. by Tamás Juhász (195396)

“…<p>PACAP 1-38 at 100 nM, PACAP 6-38 at 10 µM were applied continuously from day 1. …”

Correlation of Cervical Cancer Mortality with Fertility, Access to Health Care and Socioeconomic Indicators by Diama Bhadra Vale (6879314)

“…In the multivariate analysis, only fertility rate was significantly associated with the CC mortality rate (coefficient of correlation: 9.38; 95% confidence interval [CI]: 5.16-13.59). Conclusion A decrease in the fertility rate, as expected when the level of development of the regions increases, is related to a decrease in the mortality rate of CC. …”

Delayed degeneration of striatal neurons following icv GA administration. by Silvia Olivera-Bravo (349736)

“…<b>D:</b> Time course of number of striatal NeuN positive neurons showing a significant decrease at P21 and P45 in GA-injected animals as compared to controls. …”

Body image perception and satisfaction in university students by Ingrid Ludimila Bastos Lôbo (10422415)

“…<div><p>Abstract Body image represents the mental perception of body shapes and is a multifactorial structure that includes psychological, physical and emotional elements. …”

Heat map analysis of selected peptides. by Sayani Dasgupta (104387)

“…Bright red indicates peptides that were elevated ≥100% (ratio ≥2.00). The three groups in the heat map indicated by lines and numbers on the left margin indicate peptides which showed a large or partial decrease (set 1), little or no change (set 2), or a large increase (set 3) in response to the proteasome inhibitors. …”

Partial unwinding of backbone modified DNA substrates by BACH1-WT helicase by Rigu Gupta (22923)

“…As the dsDNA is unwound, the dye molecules are displaced (open ovals) which is measured by a decrease in the amount of fluorescence. In Scheme 1, the unmodified DNA substrate is fully unwound by the helicase, resulting in a maximal change in fluorescence. …”

Fig 11 - by Maike Stegen (8578665)

“…Actin β at approx. 40 kDa (molecular weight 43 kDa) was used as a reference on a stripped membrane. Stimulation with 100 nM PMA led to a distinct decrease in GRK6 protein expression. …”

Penile cancer trends and economic burden in the Brazilian public health system by Fernando Korkes (5910167)

“…Conclusion: Despite the decrease in admissions, penile cancer still imposes a significant economic and social burden to the Brazilian population and the Public Health System.…”

cAMP dynamics in adult mouse ventricular Epac1-camps expressing cardiomyocytes upon treatment with cAMP elevating agents and PDE4 inhibition. by Julia U. Sprenger (3387719)

“…<b>(C)</b> Representative FRET traces from Epac1-camps cardiomyocytes stimulated with the β-AR agonist isoproterenol (ISO, 100 nM) or <b>(E)</b> with the direct AC activator forskolin (10 μM) leading to an increase of cAMP visualized as a decrease in the FRET ratio. …”

Both reconnection and infiltration of LYVE-1⁺ lymphatic vessels contribute to lymphatic regeneration after tissue transfer. by Alan Yan (298075)

“…In addition, the number of recipient lymphatics in various regions of the skin graft increased significantly when comparing 2- and 6-week time points indicating ingrowth of recipient vessels. <b>E.…”

Comparison between the Uncoiling/Coiling Forces of the Fimbrial Shaft versus the Lifetime of the FimH–Mannose Bond by Manu Forero (65268)

Validation of the primary screen hits with secondary luciferase-based invasion and red-green invasion assays. by Rajshekhar Y. Gaji (417441)

“…The values obtained with non-targeting siRNA controls were set at 100% invasion. A total of 81 genes (red asterisks) showed significant decrease (<i>p</i><0.05, one sample <i>t</i>-test) in parasite invasion compared to NTsiRNA controls. …”

Expression of MMP7 and TIMP1 in wounds. by Katharina Sommer (463202)

“…Septic animals show a significant decrease in MMP7 expression on day 2 and 6 compared to control mice. …”

Glycosylation inhibitors block thrombin-induced sRBC adhesion to HUVECs. by Pushpankur Ghoshal (580530)

“…The level of sRBC adhesion to untreated HUVECs was set to 100%. **, p<0.0001 <b>B</b>. Glycosylation inhibitors decrease thrombin-induced sRBC adhesion to HUVECs. …”

Transcripts differentially expressed in response to overexpression of and in response to overexpression of human , grouped according to functional classes by Haiqiong Montalta-He (54730)

“…Positive values indicate that the relative expression level of a gene is increased (upregulated) following overexpression and negative values indicate a decrease (downregulated). …”

Astrocytic volume changes in the cortex of GFAP/EGFP and GFAP/EGFP/α-Syn^−/− mice during hypoosmotic stress. by Miroslava Anderova (155561)

“…The changes of astrocytic volume during washout were evaluated in each individual cell and expressed as an average percent of cell volume increase/decrease related to the maximal volume after 30 minutes of aCSF_H-50 (<b>C right</b>) or aCSF_H-100 (<b>D right</b>) exposure; these values were set as 0%. …”

Hormone addition results in chromatin changes at individual GR-regulated genes. by Chuong D. Pham (111374)

“…We calculate that a nucleosome/bare ratio of 1.0 corresponds to ∼50% nucleosome occupancy, while a value of 2.1 corresponds to 100% occupancy (e.g. a nucleosome covering a given location on all gene copies). …”

Histology of islet allografts at day 10, 17, 24, and 31 after transplantation in non-diabetic mice. by Jyuhn-Huarng Juang (407970)

“…There was profound immune cell infiltration at day 10 and 17, and a decrease in graft size at day 24 and 31 in the CSPIO-labeled islet graft. …”