Lkb1-deficiency alters the expression of Notch signalling components and leads to the abnormal intestinal secretory cell differentiation. by Boris Y. Shorning (232815)

“…Dll positive cells pointed with red arrows. E, Immunohistochemistry showing the localisation of Mark1 in goblet and Paneth cells both in WT (+/+) and Lkb1-deficient crypts (‘−/−’), pointed with red arrows. …”

GABAergic transmission loses importance in action potential inhibition by increasing sevoflurane concentrations. by Veit-Simon Eckle (397434)

“…Linear regression analysis depicts a decreasing role of the GABA_A receptor system at measured sevoflurane concentrations (slope −0.32±0.07, R square 0.9).…”

Interaction of the EHBP-1 CH domain with F-actin. by Peixiang Wang (352425)

“…Error bars are SEM (n = 18, 6 animals of each treatment were sampled in three different unit regions of each intestine defined by a 100 x 100 (pixel²) box positioned at random). …”

Investigation of mechanisms underlying NMR-detected changes in the levels of choline metabolites and lactate following treatment of SF188 pediatric glioblastoma cells with PI-103 (... by Nada M. S. Al-Saffar (454143)

“…(D) The time-series of the lactate peak integral normalized to cell number with inset showing the pyruvate time dependence. (E) A decrease in the rate of pyruvate-lactate exchange rate constants was detected in PI-103 treated cells compared to controls. …”

A manifestation of variance coding within the large-scale model. by Aaditya V. Rangan (305264)

“…Note that, as the total amount of synaptic-depression decreases, the discriminability computed using only firing-rates is closer to the discriminability computed using both firing-rates and -point correlations. …”

Determination of the antibacterial activity of QPEI nanoparticles in suspension. by Nurit Beyth (480476)

“…<p><b>A)</b> Viable counts of <i>E. faecalis</i> (CFU/ml) in DDW with QPEI nanoparticles determined in similarly prepared samples. …”

The TYDQYI-motif in the SBD of PauR is essential for the overall functionality of the receptor and DAR-sensing. by Sophie Brameyer (731567)

“…<p>The most drastic effects on DAR-sensing were gained with the replacement of S38A, T62A, Y66A, D75A and D75N in the SBD of PauR and a decreased effect on DAR-sensing were gained with the replacement of Y90C and I113S in PauR (lower right quadrant). …”

<i>pals-25</i> is required for increased <i>pals-5p</i>::<i>GFP</i> expression in <i>pals-22</i> mutants. by Kirthi C. Reddy (250928)

“…Scale bar, 100 μm. (F) <i>pals-5p</i>::<i>GFP</i> expression quantified in <i>pals-22</i> suppressor mutants using a COPAS Biosort machine to measure the mean GFP signal normalized by length of individual animals, indicated by green dots. …”

<i>L</i>. <i>monocytogenes</i> survival at different RH. by Fiona Zoz (2168602)

“…<p>Decrease in viability of <i>L</i>. <i>monocytogenes</i> strains, EGDe (square), CCL500 (diamond), CCL128 (triangle), and LO28 (circle), during desiccation on polypropylene coupons incubated at 25°C and 99% RH (a), 75% RH (b), 68% RH (c), 43% RH (d), and 11% RH (e) for 30, 60, 90, 120, 180, and 960 min with an instantaneous rehydration in 1 mL of PBS. …”

Protocol: Temporary Pacemaker Verification and Troubleshooting by Jill Ley (4090672)

“…<p>(Figure 1)</p> <p>(Figure 2)</p> <p><strong>Determining the Stimulation Threshold</strong></p> <ul> <li>NOTE: a paced rhythm must be present and patient stable</li> <li>From 100% pacing, gradually decrease output for A or V, while watching monitor until you lose capture</li> <li>Now gradually increase output until 1:1 capture returns – this is the stimulation threshold</li> <li>This is the lowest amount of energy that will reliably capture the heart and pace</li> <li>Set mA 1.5-3 times above this threshold value for safety</li> <li>Repeat for other circuit (A or V)</li> <li>Note: the stimulation threshold should be checked DAILY by the MD/NP when pacing is in use; in the event 
the threshold value is rising, discuss with surgeon to determine if alternative pacing system is needed</li> </ul> <p><strong>Determining the Sensing Threshold</strong></p> <ul> <li>Note: the patient must have an underlying rhythm and tolerate a brief period without pacing to perform</li> <li>Set RATE at least 10 bpm below patient’s intrinsic heart rate (to allow sensing)</li> <li>Set OUTPUT at 0.1 mA (to avoid competitive pacing when device is made asynchronous briefly)</li> <li>Highlight SENSITIVITY (under Menu 1)</li> <li>Decrease SENSITIVITY: Slowly turn dial counter-clockwise until pace indicator flashes regularly (asynchronously)</li> <li>Increase SENSITIVITY: Slowly turn dial clockwise until sense indicator flashes again (when sensing resumes, this is the sensing threshold – the smallest complex that is reliably recognized, thus inhibiting the device)</li> <li>Set SENSITIVITY < half this threshold value for safety</li> <li>Repeat for other circuit (A or V)</li> <li>Restore previous rate and output values</li> </ul> <p><strong>Rapid Atrial (Overdrive) Pacing – PERFORMED BY MD/NP/CNS ONLY</strong></p> <ul> <li>Used to “overdrive pace” and terminate some atrial reentrant tachyarrhythmias, especially atrial flutter</li> <li>ALWAYS VERIFY correct wire connections to avoid stimulating the ventricles at a rapid rate!…”

Data_Sheet_1_The combined impact of redcedar encroachment and climate change on water resources in the Nebraska Sand Hills.docx by Yaser Kishawi (12959564)

“…The most-likely climate projection indicates that a warming pattern will be expected with a 4.1°C increase in average over the 100-year period, and this will be associated with lower-than-normal precipitation (P). …”

The performance and long-term stability of low-cost separators in single-chamber bottle-type microbial fuel cells by Sanath Kondaveeti (3849310)

“…MFC operations with other size-selective separators such as SPPS, PPS, and cellulose esters exhibited power densities of 261, 231, and 250 mW/m², respectively. During a 280-day operation, initial power density of PP80 (278 mW/m²) was decreased to 257 mW/m², but this decrease was smaller than with others (Nafion: 265–230 mW/m²; PP100: 220–126 mW/m²). …”

Sulfur supply effects on production and mineral nutrition of Tanzania guinea grass under barium levels in nutrient solution by Arnon Afonso de Souza Cardoso (9980536)

“…The combinations with high S and Ba levels resulted in a decrease of 1.7-fold in leaf area compared to combinations with high S without Ba. …”

Free energy properties in cultured neural networks. by Takuya Isomura (839119)

“…<b>(D)</b> The change in 〈<i>U</i>〉, <i>H</i>, and <i>F</i> (trial 1 vs. trial 100). After training, the expectation of internal energy decreased (*, <i>p</i> = 0.023; <i>n</i> = 23 cultures), Shannon entropy significantly increased (****, <i>p</i> < 10⁻⁴; <i>n</i> = 23 cultures), and free energy significantly decreased (****, <i>p</i> < 10⁻⁴; <i>n</i> = 23 cultures). …”

DataSheet_1_Effects of the neurotoxin β-N-methylamino-L-alanine (BMAA) on the early embryonic development of marine shellfish and fish.docx by Yilei Fu (14287574)

“…A sustained and dose-dependent decrease in heart rate was apparent in marine medaka embryos at 9-days post fertilization following BMAA exposure. …”

Figure 2 by Heidi de Wit (67655)

“…Inset shows cumulative vesicle distribution in the sub-membrane region within 0–100 nm. Grey line represents the vesicle distribution in the absence of Munc18-1 as shown before <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000126#pone.0000126-Toonen2" target="_blank">[24]</a>. …”

Chemical inhibition of Igf signaling suppresses cardiomyocyte proliferation during zebrafish heart regeneration. by Ying Huang (53474)

“…(C) Quantification of BrdU positive cardiomyocytes (Mef2 positive) ± S.E. A significant decrease (*<i>p</i><0.01) in cardiomyocyte proliferation was detected in fish treated with Igf1r inhibitor NVP-AEW541.…”

DataSheet1_Physiological evaluation of PVP-coated AgNP in the rat small intestine: an ex vivo approach.pdf by Jorge Antonio Chávez-Hernández (18854947)

“…Intestinal segments (duodenum, jejunum, and ileum) were treated in the presence and absence of five cumulative, increasing concentrations of AgNP (0.01, 0.1, 1, 10, and 100 μg/mL) and three individual concentrations of PVP-coated AgNP (0.01, 1, and 100 μg/mL), showing a transient decrease in the contractile effect in the small intestine segments treated with cumulative, increasing concentrations. …”

Data_Sheet_1_Shared Species Analysis, Augmented by Stochasticity Analysis, Is More Effective Than Diversity Analysis in Detecting Variations in the Gut Microbiomes.PDF by Zhanshan (Sam) Ma (4370170)

“…The shared species analysis (SSA) is a computational technique that can discern changes of community composition by detecting the increase/decrease of shared species between two sets of microbiome samples, and it should be more sensitive than standard diversity analysis in discerning changes in microbiome structures. …”

Diversity of <i>Listeria monocytogenes</i> Strains of Clinical and Food Chain Origins in Belgium between 1985 and 2014 by S. Bertrand (3207903)

“…Since 1985, we observed a significant decrease in incidence of the Materno-Neonatal cases (from 0.15 to 0.04 cases /100,000 inhabitants-year), which is probably to be attributed to active prevention campaigns targeting pregnant women. …”