Turnover of 4MUG substrate detects GBA1 activity in mouse brain lysates in the presence of sodium taurocholate. by Zdenek Berger (440685)

“…When converted to specific activity, similar values are obtained when using 10–60 μg of mouse brain lysates, as expected. A representative experiment is shown. B) Turnover of 4MUG substrate in lysates from mouse brain is mostly due to GBA1 activity when using sodium taurocholate (NaTc). 1 mM CBE and 1 μM isofagomine (Iso) decrease the signal by ~ 80% in the presence of sodium taurocholate (+ NaTc) whereas substantially smaller reduction is seen without sodium taurocholate (- NaTc) in the assay buffer. 10 μg of protein lysate was used in the reaction. …”

3-D MicroCT images of trabecular bone microarchitecture in the distal femora in Control, OVX and OVX+PEMF rats. by Da Jing (404219)

“…The VOI started at a distance of 0.4 mm (25 slices) from the lowest end of the growth plate and extended to the proximal end of the femur with a distance of 1.6 mm (100 slices). …”

Inhibitors of Cl⁻ channels differently affect OGD-induced swelling in HR-and LR-astrocytes. by Jana Benesova (155548)

“…<p>The effect of 100 µM NPPB, a non-specific inhibitor of chloride channels (<b>A</b>), 30 µM Tamoxifen (<b>B</b>) and 30 µM DCPIB (<b>C</b>), inhibitors of volume regulated anion channels. …”

Dasatinib promotes nuclear shuttling of ER in the MCF7-TAMR cells but not the 1%MCF7. by Stephanie K. Guest (2838575)

“…<p>1%MCF7 and MCF7-TAMR cells were treated for 24-hours with 1%FBS, dasatinib (100nM), 4-OHT (10nM), or the combination and stained with ER, pSrc^tyr416 and DAPI; bars indicate 20μm <b>(A)</b>. …”

Inflammation has dual-roles during regeneration. by Suqi Zou (379705)

“…Scale bar: 10 µm (A-C, M-P); 2 µm (D); 30 µm (G), 100 µm (F, I and J).…”

Effects of the MB and its derivatives on cellular oxygen consumption rate (OCR). by Ethan Poteet (125162)

“…(D) Rotenone inhibits complex I causing a decrease in OCR, which was significantly attenuated by the treatment of MB, NR, and TB. * p<0.05 compared to control group.…”

Confocal microscopy study of the binding of Bid and caspase-8 to giant unilamellar vesicles containing cardiolipin. by Olivier Jalmar (283659)

“…The arrows indicate the decrease in GUV fluorescence following the formation of a complex between procaspase-8 and Bid_Alexa488, resulting in a non-fluorescent tBid.…”

Transitions from Bursting to Single Spiking Output Are Mediated by Slow Recovery from Na⁺ Current Inactivation by Donald C Cooper (71501)

“…The inset shows a cumulative decrease in the action potential rise rate <i>(dV/dt)</i> (τ_1Hz = 17,980 ms, τ_2Hz = 925 ms, τ_10Hz = 250 ms; <i>n</i> = 14).…”

High and low frequency transcutaneous electrical nerve stimulation in post-cesarean pain intensity by Lorenna Ellen Alves Lima (12815785)

“…At intervals after treatment, the G100 had a significant reduction of pain during all intervals (p<0.05). …”

DataSheet_1_Type VII secretion system and its effect on group B Streptococcus virulence in isolates obtained from newborns with early onset disease and colonized pregnant women.doc... by Yulia Schindler (9931351)

“…In all ST1isolates we identified two copies of esxA gene (encoding putative WXG100proteins), when only 23.5% of the ST17 isolates harbored the esxA gene. …”

Performance of decoding-based estimators depends on the dimensionality of the response trajectories and on the number of response trajectory samples. by Sarah Anhala Cepeda-Humerez (7340093)

“…<p>Performance of various model-free decoding estimators (colored lines) for Examples 1 <b>(A, D)</b>, 2 <b>(B, E)</b>, 3 <b>(C, F)</b>, respectively, compared to the MAP bound, <i>I</i>_MAP (black line), as a function of input trajectory dimension, <i>d</i> (at fixed <i>N</i> = 1000) in A, B, C; or as a function of the number of samples, <i>N</i>, per input condition (at fixed <i>d</i> = 100) in D, E, F. …”

Data Sheet 1_Particulate matter pollution and older adult health: global trends and disparities, 1991–2021.docx by Qiong Yi (3931826)

“…However, age-standardized mortality rate decreased from 384 to 337 per 100,000. HAP-SF-related deaths decreased from 2,700,000 to 2,100,000, and DALYs from 54,000,000 to 42,000,000. …”

File S1 - Diminished Vision in Healthy Aging Is Associated with Increased Retinal L-Type Voltage Gated Calcium Channel Ion Influx by David Bissig (189073)

“…Longitudinal measures from the same subject are connected by gray lines, while a white mark within a point denotes the lack of follow-up data (e.g., due to animal death). …”

Data_Sheet_1_Estimating the cost of young stock mortality in livestock systems—An application to sheep farming in Ethiopia.PDF by Joachim Otte (232257)

“…</p>Methods<p>The static zero-growth version of DYNMOD was used to calculate the annual physical and monetary output of a sheep flock consisting of 100 breeding females at different levels of lamb mortality. …”

DataSheet1_Techno-Economic Analysis of a Concentrating Solar Power Plant Using Redox-Active Metal Oxides as Heat Transfer Fluid and Storage Media.PDF by Brandon T. Gorman (11774336)

“…The cost and performance results are minimally sensitive to most design parameters. However, a one-point change in the weighted annual cost of capital from 8 to 7% (better understood as a 12.5% change) translates directly to an 11% decrease (0.66 ¢/kWhe) in the LCOE.…”

Kinetic characterizations of AChR blockade by PQ1–5. by Wan-Chen Lin (658261)

“…<p>(A) Single-channel currents of the AChR in the presence of 100 µM Ach ±5 µM <b>PQ5</b>. …”

Bacterial Surface Appendages Strongly Impact Nanomechanical and Electrokinetic Properties of <em>Escherichia coli</em> Cells Subjected to Osmotic Stress by Grégory Francius (219120)

“…In 1 mM KNO₃, cells without appendages or cells surrounded by Ag43 exhibit large Young moduli and turgor pressures (∼700–900 kPa and ∼100–300 kPa respectively). Under similar ionic strength condition, a dramatic ∼50% to ∼70% decrease of these nanomechanical parameters was evidenced for cells with appendages. …”

GBE enhanced oxygen consumption of isolated mitochondria and led to an up-regulation of mitochondrial DNA. by Virginie Rhein (243241)

“…<p><b>A</b>) Two-way ANOVA revealed a significant Aβ-induced decrease of the total cellular respiration in isolated mitochondria from APP cells compared to that of control cells (group effect: control vs. …”

<i>In vivo</i> Sema3C treatment prevents O₂-induced arrested vascular growth. by Arul Vadivel (424484)

“…<p>A. Representative photomicrographs showing von Willebrand (vWF) factor staining (brown) in RA (room air), RA+Sema3C, hyperoxia (O₂) and O₂+Sema3C exposed lungs. …”

Transcripts reduced by FRLFE in rat hepatocytes. by Ryota Yamanishi (547533)

“…The mRNA level of IL-1β was set to 100%.</p><p>(+), asRNA was experimentally detected.…”