DataSheet6_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet2_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet5_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet4_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet1_Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms.ZIP by Shaonan Hu (10728498)

“…Additionally, the treatment of FUS-Cav combined with HT block the androgen receptor (AR) signal pathway by reducing the relative Type I 5α-reductase (SRD5A1) level to 38.28 ± 3.76% in LNCap cells, and decreasing the relative Type III 5α-reductase 3 (SRD5A3) level to 22.87 ± 4.88% in PC-3 cells, in contrast, the relative SRD5A level in untreated groups was set to 100%.…”

DataSheet_1_Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.pdf by Xue Yi (12115359)

“…Single agent exposure induced some apoptosis but combination of 100 nM venetoclax and 100 or 300 nM of AMG-176 resulted in 40–100% cell death in baseline samples. …”

DataSheet_2_Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.pdf by Xue Yi (12115359)

“…Single agent exposure induced some apoptosis but combination of 100 nM venetoclax and 100 or 300 nM of AMG-176 resulted in 40–100% cell death in baseline samples. …”

The effect of stress on sound processing increases with repeated exposure. by Ghattas Bisharat (20706928)

“…We found a negative slope in most PPY and PV cells, indicating a decrease in activity as the stress becomes chronic (<i>t</i> test for PPY cells <i>p</i> = 9.8 × 10⁻¹⁴, PV cells <i>p</i> = 0.006) and a positive slope for SST cells indicating an increase in activity with successive applications of the stressor (<i>t</i> test for SST cells <i>p</i> = 9.5 × 10⁻⁰⁶). …”

Chile’s 2014 sugar-sweetened beverage tax and changes in prices and purchases of sugar-sweetened beverages: An observational study in an urban environment by Juan Carlos Caro (4707607)

“…<div><p>Background</p><p>On October 1, 2014, the Chilean government modified its previous sugar-sweetened beverage (SSB) tax, increasing the tax rate from 13% to 18% on industrialized beverages with high levels of sugar (H-SSBs) (greater than 6.25 grams [g] sugar/100 milliliters [mL]) and decreasing the tax rate from 13% to 10% on industrialized beverages with low or no sugar (L-SSBs) (less than 6.25 g sugar/100 mL). …”

Table 6_Global burden of chronic kidney disease due to hypertension attributable to dietary risks in adults aged 25 years and older: findings from the global burden of disease stud... by Lianjie Huang (21775979)

“…Background<p>Suboptimal diet remains a major threat to chronic kidney diseases (CKD) and hypertension, however, the burden of diet-attributable CKD due to hypertension (HCKD) has been poorly quantified and reported. …”

Comparison between α1β2γ2 and α3β2γ2 GABA-channel currents elicited by brief GABA applications by Andrea Barberis (74413)

“…Journal Compilation © Federation of European Neuroscience Societies and Blackwell Publishing Ltd</p> (A) Multiple records of 1 s illustrating channel activity evoked by 2 ms applications of GABA to outside-out patches in two patches excised from human embryonic kidney (HEK) cells expressing single α1β2γ2 (left, 10 m GABA) and α3β2γ2 (right, 50 m GABA) channels (holding potential, −100 mV). …”

SipC-dependent relocalization of phosphatidylinositol-4,5-bisphosphate (PI₄₅P2) drives synergy with SopB. by Robert J. Cain (272233)

“…Table shows differences in invasion rates (%) after correction. Shading denotes a significant increase (green), significant decrease (red) or no significant change (grey) in invasion (Mann Whitney U p<0.05). …”

Data_Sheet_1_Dynamic electrophysiological mechanism in patients with long-standing persistent atrial fibrillation.docx by Emilio Osorio-Jaramillo (13877585)

“…However, individual zones showed a high number of quantitative changes (increase/decrease) of driver activity. …”

<i>TcPiezo-CKO</i> responses to hypoosmotic stress. by Guozhong Huang (673424)

“…(D) Tet-induced <i>TcPiezo2 Tet-OFF</i> cells (+Tet) had a significant decrease of intracellular Ca²⁺ rise, compared to non-induced cells (-Tet). 100 µ M EGTA was added to remove extracellular Ca^2<i>+</i>, abolishing Ca²⁺ entry, as indicated. …”

Data Sheet 1_Global burden of chronic kidney disease due to hypertension attributable to dietary risks in adults aged 25 years and older: findings from the global burden of disease... by Lianjie Huang (21775979)

“…Background<p>Suboptimal diet remains a major threat to chronic kidney diseases (CKD) and hypertension, however, the burden of diet-attributable CKD due to hypertension (HCKD) has been poorly quantified and reported. …”

<i>Ras</i> cells show elevated checkpoint activity in response to treatment with cytarabine, daunorubicine or etoposide. by Mona Meyer (257592)

“…<p>(A) Phosphorylation of Chk1 in response to cytarabine treatment is dose-dependent and elevated in <i>Ras</i> cells. …”

Characteristics of stroke patients. by Yeo Hyung Kim (10338764)

“…Higher nonhemiplegic calf circumference (OR, 0.80; 95% CI, 0.67–0.96; p = 0.02) was associated with a lower likelihood of possible sarcopenia. We conclude that tube feeding, high stroke severity, decreased nonhemiplegic calf circumference, and older age are independent risk factors for possible sarcopenia in patients with subacute stroke.…”

XIAP promoted HCT116 cell migration and invasion. by Jinyi Liu (325830)

“…The asterisk (*) indicates a significant decrease compared with that in WT cells (<i>p</i><0.01).…”

In vivo assessment of YM155 using a patient-derived RCC xenograft model in SCID mice. by Mei Yi Sim (4067998)

“…(A) The mean tumour volume of vehicle- and YM155- treated mice at the given time-points showed a decrease in the rate of tumour growth at higher doses of YM155. …”

Conventional approach in programming the static nonlinearity artificially constrained the dynamic range of prostheses to an unnaturally narrow band. by Kantapon Pum Wiboonsaksakul (13794446)

“…<p>(<b>A</b>) Schematic of the VOR generation in a monkey implanted with the prosthesis. …”