An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

<i>Becn1</i>^FA/FA mutation ameliorates cerebral Aβ accumulation, memory deficits and mortality of Alzheimer’s mouse models. by Altea Rocchi (3278457)

ALDH2 inhibitors decrease stroma-induced ALDH activity in AML cells and sensitize them to chemotherapy. by Bin Yuan (19897)

Neuronal cell cultures derived from embryos injected with APPb-MO had decreased neurite length. by Ping Song (169215)

“…The neurons from the embryos injected with 8 ng of APPb-MO showed a decrease in neurite length compared to neurons from the control embryos (un-injected). …”

Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in S4 Table) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE.... by Michael J. Johnson (5818168)

“…<p>Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1013759#ppat.1013759.s004" target="_blank">S4 Table</a>) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE. …”

Total number of hippocampal microRNAs that are increased or decreased after SE at each time point. by Rashmi M. Risbud (290321)

IL-2 accumulation decreases in response to viable <i>P. gingivalis</i> and its derived supernatant. by Hazem Khalaf (308041)

Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center by Shiying Tang (5137418)

“…Among the 132 patients with PCa, prostate specific antigen (PSA) analysis was available in 76 patients (57.6%), with a median value of 1.06ng/mL, and 61 (80.3%) patients had a PSA value below 4ng/mL. …”

Increase of Viral Dose and Addition of Mosquito Salivary Gland Extracts (SGE) Decrease circulating Viral RNA. by Anne M. Wertheimer (359266)

<i>Becn1</i>^F121A leads to autophagy hyperactivation in vivo. by Altea Rocchi (3278457)

Decreased miR-24 sensitizes cells to apoptotic stimuli, and increases pro-apoptotic protein expression. by Tan Nguyen (278146)

“…<b>A</b>) 32Dcl3 and knockdown cells were washed out of 10 ng/ml IL-3 containing media. …”

Western blot experiments demonstrating that TGF-β1 decreases CFTR protein abundance in HBE cells. by Steven M. Snodgrass (587391)

“…(<b>B</b>) Representative experiment demonstrating that TGF-β1 decreases WCL CFTR in a time-dependent manner. TGF-β1 (15 ng/ml) or vehicle control (CTRL) was added to the basolateral medium and cells were incubated for 24 h. …”

Decreased Expression of MiRNA-204-5p Contributes to Glioma Progression and Promotes Glioma Cell Growth, Migration and Invasion by Zhiqiang Xia (764303)

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

Down-regulation of Bim in EBV-positive cells is not due to proteosomal degradation or decreased mRNA stability. by Kostas Paschos (262658)

Waning of BCG-induced protection against <i>Mtb</i> coincides with decreased T-cell functional capacity. by Subhadra Nandakumar (212501)

AMPK activators reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

“…<p>(A) Representative western blot images (upper) and summarized data (lower) showing the effects of AICAR (n = 5 for each group) (A), ASP (n = 4 for each group) (B), and MET (n = 7 for each group) (C) on DEX-induced decreases of GR and pAMPK in cultured astrocytes. …”

Exposure to glucocorticoids decreases the levels of pAMPK and GR in cultured rat prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

Decreased CD39 protein expression by islet resident macrophages heralds T1D in NOD mice. by Thomas B. Thornley (2550766)

Decreased expression of SMAD1/5/8 and VEFG in the Botox injected side MCC and subchondral bone. by Eliane H. Dutra (3207312)