6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

Time-adjusted survival curve for IL-6 and renalase among patients with COVID-19 disease (A) For composite outcome^a: High renalase + High IL-6; High renalase + Low IL-6;... by Basmah Safdar (12213257)

Ppk1 levels are not affected by decreasing dendrite arbor size but are reduced when dendrite length increases. by Josephine W. Mitchell (17364781)

Delayed boosting with ALVAC-HIV/AIDSVAX B/E or AIDSVAX B/E increases breadth of Env-specific IgG response. by LaTonya D. Williams (3140490)

Laminar flow increases the expression of anti-oxidant genes and decreases the inflammatory basal state of GEnC. by Daan C. ‘t Hart (10751645)

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)

Delayed boosting with ALVAC-HIV/AIDSVAX B/E or AIDSVAX B/E increases IgG and IgG1 breadth. by LaTonya D. Williams (3140490)

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

“…</p><p>Methods</p><p>We used a mathematical model to compare three potential ART initiation criteria: 1) CD4 <350/μL (<i>ART<350/μL</i>); 2) CD4 <500/<i>μ</i>L (<i>ART<500/μL</i>); and 3) ART at presentation (<i>Immediate ART</i>). …”

ALDH2 inhibitors decrease stroma-induced ALDH activity in AML cells and sensitize them to chemotherapy. by Bin Yuan (19897)

Pep4 overexpression decreased APCs in Vps21- and ESCRT-mutant cells after nitrogen starvation. by Zulin Wu (4451572)

“…Either Pep4 or Snf7 in <i>snf7Δ</i> cells facilitated GFP-Atg8 degradation and prApe1 maturation (bottom), but only Snf7 (not Pep4) promoted phagophore closure in <i>snf7Δ</i> cells. The red arrows point to these key results. <b>F.</b> Quantification of the immunoblot results shown in panel E was performed as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010431#pgen.1010431.s008" target="_blank">S8F Fig</a>. …”

Change from full-scale to reduced model in sum (across all time points and grids) of squared error between model and MC scan data as a function of the number of clusters used in th... by Monica E. Shapiro (22622240)

Response of small airway tissues infected with EV-D94 and decreasing doses of EV-D68. by Ines Cordeiro Filipe (5849144)

“…<p>Tissues were infected with 1E7 RNA copies of EV-D94 (equivalent to 2,46E4 TCID50) and 1E7 RNA copies of EV-D68 (3,3E5 TCID50) as well as decreasing doses of the latter. …”

datasheet1_Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage.docx by Ana Paula S. Dornellas (9983996)

“…As allopregnanolone is a potent positive allosteric modulator of GABA_A receptors, and GABA_A receptors can regulate dopamine release, we hypothesized that allopregnanolone would reduce phasic fluctuations in mesolimbic dopamine release that are important in learning and reward processing. …”

Kcnk5b requires CaMKK for growth and SHH/<i>shha</i> expression. by Xiaowen Jiang (8291814)

Supplementary Material for: Clinical Implications of Decreased Computed Tomography Value after Ramucirumab in Advanced Gastric Cancer by Izawa N. (6834062)

“…<b><i>Objectives:</i></b> This study aimed to evaluate whether a decrease of computed tomography (CT) value for tumors serves as a predictive marker in patients with advanced gastric cancer (aGC) who have undergone chemotherapy with vascular epithelial growth factor receptor 2 inhibitor (ramucirumab). …”

Supplementary Material for: Enhanced Recovery after Surgery for Radical Cystectomy Decreases Postoperative Complications at Different Times by Lannes F. (11465377)

“…<b><i>Methods:</i></b> We performed a retrospective monocentric study using prospectively maintained databases including all patients treated by radical cystectomy between January 2015 and July 2019. …”

Table_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.docx by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_3_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”