SapA is required for NTHI to directly counter host defensin lethality <i>in vivo.</i> by Catherine L. Shelton (340365)

“…Black and gray horizontal lines (panels A and B) represent the geometric mean value of each cohort (n = 5 animals per cohort). …”

Potential signatures of adaptive introgression at <i>SLC30A9</i>. by Ana Roca-Umbert (17041620)

“…Each column corresponds to a polymorphic position with a homozygous genotype in the Denisovan (112 in total; see details in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010950#pgen.1010950.s042" target="_blank">S4</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010950#pgen.1010950.s043" target="_blank">S5</a> Tables), each row is a phased haplotype, colored according to the population of origin of the individuals shown in the top. …”

Rad51 paralogs and the risk of unselected breast cancer: A case-control study by Peter Grešner (3533093)

“…In <i>Xrcc3</i>, the ⁴⁵⁴¹A/⁹⁶⁸⁵A haplotype was found to be significantly associated with reduced BrC risk (OR = 0.5; 95% CI: 0.3–0.9; p<0.05). …”

Supplementary Material for: Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model by Kourula S. (4444969)

“…Twenty-four hours after exposure to 60 µM FH, a decrease in viability of 80% was found, compared with no decrease after exposure to 60 µM MHA. …”

Data_Sheet_1_A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity—Analysis of all Genotypes and Ph... by Wen-I Lee (474051)

“…This patient had the common variable immunodeficiency (CVID) phenotype and received regular immunoglobulin infusions over 20-years; he gradually developed nodular regenerative hyperplasia over a 5-year period. Distinct from the previously reported CD3G mutations, which mainly present as autoimmunity, the novel CD3G deletion (c.del213A) in our patient caused an obvious decrease in switched memory B cells and diminished CD40L expression. …”

Impact on child acute malnutrition of integrating a preventive nutrition package into facility-based screening for acute malnutrition during well-baby consultation: A cluster-rando... by Elodie Becquey (3822208)

“…We hypothesized that the integration of a preventive package including age-appropriate behavior change communication (BCC) on nutrition, health, and hygiene practices and a monthly supply of small-quantity lipid-based nutrient supplements (SQ-LNSs) to the monthly screening would increase AM screening and treatment coverage and decrease the incidence and prevalence of AM.…”

Table_2_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.docx by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

Table_1_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.DOCX by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

Image_1_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.JPEG by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

Image_2_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.JPEG by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

STEM: a tool for the analysis of short time series gene expression data-2 by Jason Ernst (24617)

“…The data was sampled at five time points 0 h, .5 h, 3 h, 6 h, and 12 h. The data set was filtered to contain only the 2989 genes with no missing data (though STEM can handle missing data without filtering, see ) that exhibited a .8 log base two fold increase or decrease for at least one time point. …”

Effects of FGF-2 and/or a soft substratum on TGF-β-induced expression of α-SMA. by Tomoyo Matsumura (9656681)

“…The induction of α-SMA by TGF-β2 was decreased on a soft substratum in the softness-dependent manner. …”

A J-Like Protein Influences Fatty Acid Composition of Chloroplast Lipids in Arabidopsis by Imad Ajjawi (200926)

“…T-DNA mutants in the poorly annotated <em>Arabidopsis thaliana</em> gene At1g08640 were identified as containing moderately high levels (50–100%) of 16∶1Δ7 and 18∶1Δ9 leaf fatty acids and subtle decreases (5–30%) of 16∶3 and 18∶3 (<a href="http://www.plastid.msu.edu/">http://www.plastid.msu.edu/</a>). …”

Internal Thoracic Impedance - A Useful Method for Expedient Detection and Convenient Monitoring of Pleural Effusion by Gideon Charach (731133)

“…Prominent changes were observed in the respiratory rate of the study group: there was a decrease from 31.2±4.0 to 19.5±2.4 ohm (35.2%) compared to no change for the controls, and a mean increase from 83.6±5.3%-92.5±1.6% (13.2%) in O2 saturation compared to 94.2±1.7% for the controls. …”

A Reappraisal of the Mechanism by Which Plant Sterols Promote Neutral Sterol Loss in Mice by Gemma Brufau (215229)

“…PS feeding resulted in a dose-dependent decrease of fractional cholesterol absorption (∼2–7-fold reduction) in wild-type mice and ∼80% reduction in Abcg5^-/- mice. …”

Friendship as a social mechanism influencing body mass index (BMI) among emerging adults by Meg Bruening (4766967)

“…</p><p>Results</p><p>At baseline, mean BMI was 24.2±4.5 kg/m². Overall, mean BMI increased over time; individual decreases in BMI were uncommon. …”

Effects of mismatched crRNAs on Cas12a-mediated phage defense. by Michael A. Schelling (15295682)

“…<p>(A) Schematic of crRNA expression and processing by FnCas12a and crRNA phage target locations. crRNA mismatches were introduced by mutating individual nucleotides in the spacer sequence. …”

Analysis of tumour vasculature with the addition of more USMB groups. by Deepa Sharma (278210)

Model response characteristics produced as a result of adjusting AMPA and NMDA conductance levels. by Cal F. Rabang (191595)

“…<p>Y-axis values correspond to AMPA conductance (0 – 20 nS), X-axis values correspond to ratio of NMDA to AMPA conductance (0, .5, 1, 1.5, 2, 2.5, 3). Values of AMPA conductance and NMDA:AMPA ratio chosen for Large and Small IC inputs are identified by a white L and S on the 100 ms color plots, respectively. …”

Lovastatin treatment results in actin disorganization and inhibits VEGF induced rhoA activation. by Tong T. Zhao (361937)

“…<p>A, Actin cytoskeletal organization was visualized using rhodamine-conjugated phalloidin following 24 hr 0.5, 2 and 5 µM lovastatin treatments of HUVEC. …”