Leukocyte infiltration signatures of human psoriasis and mouse psoriasiform lesions. by William R. Swindell (175427)

“…However, for each cell population, we identified human transcripts associated with genes orthologous to the <i>n</i> signature transcripts, and among these human transcripts, we evaluated the ratio of psoriasis-increased to psoriasis-decreased transcripts.…”

datasheet1_Hepatic Cytochrome P450 Abundance and Activity in the Developing and Adult Göttingen Minipig: Pivotal Data for PBPK Modeling.docx by Laura Buyssens (10651334)

“…In general, CYP protein abundance gradually increased during development. However, we observed a stable protein expression over time for CYP4A24 and CYP20A1 and for CYP51A1, a high protein expression during the fetal stages was followed by a decrease during the first month of life and an increase toward adulthood. …”

Gli1 slowed proliferation of NB cell lines while driving CGNPs to proliferate. by Timothy R. Gershon (258247)

“…<p>A) Transduction of <i>Gli1</i> decreased proliferation of NB cell lines SY5Y, BE2(N), BE2(C) and BE2(S). …”

Epidemiological and Clinical Characteristics and Risk Factors for Death of Patients with Avian Influenza A H7N9 Virus Infection from Jiangsu Province, Eastern China by Hong Ji (293468)

“…Finally, dynamic monitoring showed that lymphopenia was more significant in fatal group than in nonfatal group from day 11 to week five (<i>P</i><0.05). The decrease in oxygenation indexes were observed in most cases and more significantly in fatal cases after week three (<i>P</i><0.05), and the value of nearly all fatal cases were below 200 mmHg during our evaluation period.…”

CDA deficiency leads to excess dCTP, inhibiting PARP-1 activity and leading to UFB formation. by Simon Gemble (168663)

“…<p>(A) Relative number of PAR foci in HeLa-Ctrl_(CDA) (black bars) and HeLa-shCDA (gray bars) cell lines treated with 1 mM dC. Error bars represent means ± SD for five independent experiments (> 1,200 cells per condition). …”

Image_1_Short-term effects of ophthalmic topical 0.01% atropine on the ocular surface, pupil size, and subsequent subjective quality of vision in young myopic Chinese adults.jpg by Mingze Li (4020185)

“…</p>Methods<p>Thirty-three adults (66 eyes) were recruited for the study. The mean age of the participants recruited for this study was 24.91 ± 3.36 years. …”

Mapping dendritic spine loss with CBV-fMRI and volumetric MRI. by Xinyang Feng (9182526)

“…The t-value distribution of CBV decrease during 30-day trimming period across cortical regions shows that the barrel cortex on the control side (right hemisphere) has significant CBV decreases (<i>p</i><0.05, cluster>20) and the barrel cortex contralateral to the trimmed side (left hemisphere) has no clear CBV decreases. …”

Resection requires Ctp1, Mre11, and Exo1, but not Rqh1, and can be inhibited by Ku. by Petra Langerak (6714)

“…Resection at 35 bp from the break is decreased in the absence of either Mre11 or Ctp1. B. …”

Oxygen Consumption Rates (OCR) and respiration parameters in Aur treated N27 cells. by Pamela Lopert (114596)

“…(e) Proton Leak was increased in cells treated with PQ alone or combined with Aur. α = p<0.05 compared to control, β = p<0.05 compared to 100 nM Aur, χ = p<0.05 compared to 300 nM Aur, φ = p<0.05 compared to 100 µM PQ (n = 5−15) as determined by 1-way ANOVA. Bars represent mean ± SEM.…”

Bioenergetic analysis of Opa1 morphants. by Jennifer J. Rahn (343062)

“…<p>Oxygen consumption rates (OCR) were measured in 24, 48, and 72 hpf morphants (mean +/− SEM, n = 5–10). <b>A.</b> Opa1 morphant basal respiration was significantly decreased compared to MMC morphants at 24 and 72 hpf (p = 0.004 (a) and p = 0.0007 (b), respectively). …”

Disruption of core-AP2M1 binding abolishes recruitment of AP2M1 to LD and alters the sub-cellular localization of core and its colocalization with E2. by Gregory Neveu (142972)

“…TGN46 (green), demonstrating decreased localization of core to TGN in Huh-7.5 cells electroporated with J6/JFH RNA harboring the Y136A core mutation (right panel) compared with WT core (left panel). …”

Conditional RAX-Cre-mediated ablation of <i>Prss56</i> from fully differentiated Müller glia leads to ocular size reduction. by Seyyedhassan Paylakhi (4951933)

“…CRE expression was induced by tamoxifen injection at P8, a time point preceding complete Müller glia differentiation. …”

Opposing regulation of ARE-driven reporter genes by distinct Nrf1 isoforms. by Yiguo Zhang (512679)

“…(<b>C</b>) Total lysates of COS-1 cells expressing each of Nrf1 isoforms or Nrf2 were resolved by 12% SDS-PAGE in a Bis-Tris buffer system and visualized by immunoblotting with the V5 antibody. The position of migration of the V5-tagged polypeptide was estimated to be 120, 95, 55, 46, 38, 36 and 25 kDa, and GAPDH was used as an internal control to verify amounts of proteins loaded into each electrophoretic well. …”

Effects of adenosine receptor antagonists on abacavir-induced relaxation of rat basilar arteries. by Rachel Wai Sum Li (422494)

“…(B) Sample trace showing the effects of CGS-15943 and ZM-241385 on abacavir-induced relaxation. Values are means ± S.E.M of four to five sets of experiments and statistical comparisons were made using ANOVA. …”

AZD1775 induces toxicity through double-stranded DNA breaks independently of chemotherapeutic agents in p53-mutated colorectal cancer cells by Peter John Webster (3838426)

“…AZD1775 significantly improved the cytotoxicity of 5-FU in a p53-mutated colorectal cancer cell line (HT29 cells), decreasing the IC₅₀ from 9.3 μM to 3.5 μM. …”

Data_Sheet_1.pdf by Xinyu Wang (341591)

“…The PNP degradation efficiency of a biocathode BES with 0.5 V (Bioc-0.5) reached 99.5 ± 0.8%, which was higher than the degradation efficiency of the BES with 0 V (Bioc-0) (62.4 ± 4.5%) and the OC-BES (59.2 ± 12.5%). …”

<em>Pseudomonas</em> Evades Immune Recognition of Flagellin in Both Mammals and Plants by Bart W. Bardoel (208106)

“…In our search for Toll like receptor (TLR) antagonists, we screened bacterial supernatants and identified alkaline protease (AprA) of <em>Pseudomonas aeruginosa</em> as a TLR5 signaling inhibitor as evidenced by a marked reduction in IL-8 production and NF-κB activation. …”

Associations between air pollution and cardio-respiratory physiological measures in older adults exercising outdoors by David Stieb (3547763)

“…In the control group, an interquartile range increase in fine particulate matter (PM_2.5) was associated with increases of 1.4% in heart rate (standard error (SE) = 0.7%) and 5.6% (SE = 2.6%) in malondialdehyde, and decreases of 5.6% (SE = 2.5%) to 16.5% (SE = 7.5%) in heart rate variability measures. …”

The application of nano-enrichment in CTC detection and the clinical significance of CTCs in non-small cell lung cancer (NSCLC) treatment by Tengteng Wei (7041785)

“…During six chemotherapy cycles, the average CTC number decreased from 5.8/7.5 ml in cycle #1 to 2.4/7.5 ml in cycle #4 and remained at almost the same level from 4 to 6 cycles. …”

pX interacts directly with the Bro1 domain of ALIX. by Takayoshi Shirasaki (10098660)

“…Results shown are means ± s.e.m. from n = 3 independent experiments.</p>…”