Cartoon schematic of quorum sensing in <i>Vibrio cholerae.</i> by Andrew M. Guarnaccia (11476147)

Expression of tight junction proteins. by Maj Schneider Thomsen (10297019)

“…<p>(A) Relative gene expression of claudin-1,-3,-5 (<i>Cld1</i>, <i>Cld3</i>, and <i>Cld5</i>), occludin (<i>Ocln</i>), and zonula occludens 1 and 2 (<i>Zo1</i>, <i>Zo2</i>) in mouse, rat, and porcine brain capillary endothelial cells (mBECs, rBECs, pBECs) cultured as mono-culture (black triangle) and as co-culture with primary astrocytes (blue circle). …”

Data_Sheet_1_The Effects of Superimposed Whole-Body Electromyostimulation During Short-Term Strength Training on Physical Fitness in Physically Active Females: A Randomized Control... by Ulrike Dörmann (6050165)

“…Twenty-two active female participants (n = 22; mean ± SD: age: 20.5 ± 2.3 years; height: 171.9 ± 5.5 cm; body mass: 64.0 ± 8.2 kg; strength training experience 5.1 ± 3.6 years) were randomly assigned to two groups: strength training (S) or strength training with superimposed WB-EMS (S+E). …”

Effect of apicomplexan infections on the scallop condition. by Árni Kristmundsson (838846)

“…The first on the left is from 7.8 cm scallop which has severe macroscopic changes (grade 3; MI = 1.4), it is brownish coloured and greatly diminished and extensively infected while the first on the right is from 7.2 cm healthy looking one with firm and light coloured adductor muscle (MI = 2.5) which had a mild apicomplexan infection. The one in the middle is from a 7.5 cm scallop with grade 1 macroscopic changes (MI = 1.9). …”

Additional measures to characterize (A) actin filament and (B) motor protein organization in simulations using baseline parameter values (Table 1). by Maria-Veronica Ciocanel (9565099)

“…<p>(A1) The radius of gyration, a measure of filament network contractility (§ 5.1), shows little change over time but with high variability around the mean. …”

Size effects on dislocation starvation in Cu nanopillars: a molecular dynamic simulations study by G. Sainath (17069218)

“…Furthermore, we define the dislocation starvation strain and based on this, it has been shown that the contribution of the dislocation starvation to the total plastic strain decreases from 70% in small-sized nanopillars to below 5% in large-sized pillars. …”

The global impacts of US climate policy: a model simulation using GCAM-TU and MAGICC by Han Chen (228557)

“…</p><p>To meet the 2°C target without the US means increased reduction efforts and mitigation costs for the rest of the world, and considerable economic burdens for major developing areas.…”

Hhat KD inhibits Hh-mediated juxtacrine/paracrine signaling. by Antonios D. Konitsiotis (532086)

“…The data shown are representative of five independent experiments and are the means ± standard error of triplicates. …”

Longitudinal Changes in Sex Hormone Binding Globulin (SHBG) and Risk of Incident Diabetes: The Study of Women's Health Across the Nation (SWAN) by Monique M. Hedderson (17761480)

“…Compared to the lowest quartile for annual rate of change of SHBG since baseline [Q1 (-92.3 to -1.5 <i>n</i>M], all other quartiles were associated with a decreased risk of diabetes adjusting for covariates and baseline SHBG; associations persisted after adjusting for rate of change of T and E2 [Q2 (>-1.5 to -0.2<i> </i><i>n</i>M) HR 0.33 (0.23,0.48); Q3 (>-0.2 to 1.3 <i>n</i>M) HR 0.37 (0.25, 0.55); Q4 (>1.3 to 82.0 <i>n</i>M) HR 0.43 (0.30, 0.63)].…”

The effect of the PI3K inhibitor LY294002 (LY) on the cell viability and the [Ca²⁺]_i of primary cultured SD rat retinal cells in H₂O₂ in... by Yan Feng (128912)

“…<p>A: Western blot results of the activation of the PI3K/Akt pathway after βE2 treatment for 0.5 hrs; B: Quantitative data of A; C, E, G, and I: Cell viability quantitative data; D, F, H, and J: [Ca²⁺]_i quantitative data; C and D: The effects of LY treatments for 24 hrs and 0.5 hrs on the cell viability and the resting [Ca²⁺]_i; E and F: The inhibitory effect of LY pretreatment for 0.5 hrs on the increased cell viability and [Ca²⁺]_i induced by 10 μM βE2 treatment for 0.5 hrs (10 μM LY in E, 10 μM and 20 μM LY in F); G and H: The effect of LY pretreatment for 0.5 hrs on the decreased cell viability and increased [Ca²⁺]_i induced by 100 μM H₂O₂ treatment for 2 hrs (10 μM LY in G, 10 μM and 20 μM LY in H); I and J: The dose-dependent attenuating impact of 20-50 μM LY pretreatment for 0.5 hrs on the βE2 retinal protective role against H₂O₂ injury, which is associated with the dose-dependent attenuation of the increased [Ca²⁺]_i (Protocol of drug application: LY for 0.5 hrs, E2 for 0.5 hrs and H₂O₂ for 2 hrs). …”

The Impact of Company-Level ART Provision to a Mining Workforce in South Africa: A Cost–Benefit Analysis by Gesine Meyer-Rath (144675)

“…As ART coverage increases from 10% to 97% of eligible employees, increases in survival and retention of HIV-positive employees and associated reductions in absenteeism and benefit payments lead to cost savings compared to a scenario of no treatment provision, with the annual cost of HIV to the company decreasing by 5% (90% credibility interval [CrI] 2%–8%) and the mean cost per HIV-positive employee decreasing by 14% (90% CrI 7%–19%) by 2022. …”

Data_Sheet_1_Molecular epidemiological characteristics of Mycobacterium leprae in highly endemic areas of China during the COVID-19 epidemic.docx by Jiaojiao Zhou (432827)

“…</p>Results<p>There was an 18.97% decrease in the number of counties and districts reporting cases. …”

Cell viability in H727 cells: H727 cells were pre-treated with lovastatin for 24h before everolimus was added, and the combination of both drugs was incubated for 48h (A) or 120h (... by Svenja Nölting (566453)

“…(A) Treatment with 5–20 μM lovastatin or with 10 nM everolimus alone significantly decreased H727 cell viability. …”

Normalized NO signal transduction pathway in the penis of Sickle mice by sildenafil treatment. by Trinity J. Bivalacqua (429540)

“…<p>Continuous sildenafil citrate treatment increases basal calcium-dependent NOS activity (a; n = 6), cGMP levels (b; n = 7), PDE5 activity (d; n = 6), and PKG activity (e; n = 6), and decreases neurostimulated cGMP levels (c; n = 7) in the penis of Sickle mice. …”

The effect of FK506 on TREM-1 expression in RAW264.7 cells. by Weilan Huang (583018)

“…ELISA data (D) demonstrated that sTREM-1 protein expression decreased at 24 h post-stimulation. The data are presented as the mean ± SEM and represent 3 individual experiments, with 5 groups of cells at each time point (***<i>P</i><0.001).…”

Image_2_Knockdown of LMTK3 in the Endometrioid Adenocarcinoma Cell Line Ishikawa: Inhibition of Growth and Estrogen Receptor α.tif by Guiyang Cai (11584636)

“…We detected the effects of LMTK3 on cell viability of Ishikawa cells by CCK-8. …”

Image_1_Knockdown of LMTK3 in the Endometrioid Adenocarcinoma Cell Line Ishikawa: Inhibition of Growth and Estrogen Receptor α.tif by Guiyang Cai (11584636)

“…We detected the effects of LMTK3 on cell viability of Ishikawa cells by CCK-8. …”

Visualization of pathways, interacting network, and validation of selected downstream regulators. by Soumya Panigrahi (188599)

“…In all the immunoblots, lane 1 from no-treatment control cells, lane 2 is from Tat-GFP treated cells, lane 3 is from Tat-apoptin treated cells respectively for both cell lines. STAT5 phosphorylation was significantly inhibited by apoptin indicating that apoptin induced inhibition of Bcr-Abl phosphorylation decreases the activation of STAT5 through phosphorylation. …”

Chromosomal integration of HPV16 genomes causes host transcript modulation through host:host interaction changes within TADs. by Ian J. Groves (8703930)

“…<p>(A) Comparative analysis of Hi-C libraries between clones G2 and D2 shows significant differentially interacting regions (DIRs) within the TAD of integration (red–increased host:host interactions in clone G2 vs D2; blue–decreased host:host interactions in clone G2 vs D2), including the decreased interaction in clone G2 between the <i>ARL15</i> locus/TAD boundary (Chr5: 53.52Mbp, turquoise arrowhead) and the locus between <i>MOCS2</i> and <i>FST</i> (Chr5: 52.4Mbp, orange arrowhead), highlighted as a ‘yellow outlined triangle’. …”

Improving the Modeling of Disease Data from the Government Surveillance System: A Case Study on Malaria in the Brazilian Amazon by Denis Valle (197557)

“…Our simulations reveal that trends in the number of disease cases do not necessarily imply similar trends in infection prevalence or incidence, due to the strong influence of concurrent changes in sampling effort. We also show that ignoring decreases in the pool of infected individuals due to the treatment of part of these individuals can hamper reliable inference on infection incidence. …”