Long-term treatment with rapamycin affects spatial learning. by Zhenya Lu (780517)

“…Rapamycin-treated rats at the dose of 1.0 and 3.0 mg/kg resulted in significant increase in escape latency (B) and swimming length (C) and decrease in number of crossing the target (D) on the 5th day. …”

Peptides selected for evaluation. by Paul M. Armistead (210401)

“…The peptide containing the recipient allele-associated amino acid (shown in bold) that was predicted to bind most tightly to HLA-A0201 according the IEDB (SMM) and SYFPEITHI algorithms are shown in column 5 with IEDB and SYFPEITHI prediction scores in columns 6 and 7 respectively. …”

miR-147 reverses mesenchymal phenotype. by Chang Gong Lee (509341)

“…MTT assay showed that the OD at 490 nm values of miR-147-transfected HCT116 and SW480 Cells decreased significantly compared to negative control miR transfected cells, (p = 1.9e-5, and p = 0.013 respectively). …”

Table_1_Highly diverse microbial community of regenerated seedlings reveals the high capacity of the bulb in lily, Lilium brownii.xlsx by Sauban Musa Jibril (11358471)

“…After the regeneration of seedlings from bulbs, there was a significant increase in the number of detectable microbial species, and after 1, 3, and 5 successive generations, there was a decrease in the number of detectable species. …”

MicroRNA Profiling of Neurons Generated Using Induced Pluripotent Stem Cells Derived from Patients with Schizophrenia and Schizoaffective Disorder, and 22q11.2 Del - Fig 2 by Dejian Zhao (552133)

“…<p>A. miRNA-seq reads (y-axis) for controls (ctrl) and patients with 22q11.2 del (SZ) showing two, nominally significant up-regulated genes (miR-23a-5p and miR-146b-3p), a miRNA that showed a genome wide significant decrease in expression (miR-185-5p), and a miRNA that showed no difference in expression (miR-767-5p). …”

Data_Sheet_1_Highly diverse microbial community of regenerated seedlings reveals the high capacity of the bulb in lily, Lilium brownii.docx by Sauban Musa Jibril (11358471)

“…After the regeneration of seedlings from bulbs, there was a significant increase in the number of detectable microbial species, and after 1, 3, and 5 successive generations, there was a decrease in the number of detectable species. …”

Effect of DNP and phalloidin on anhydrobiotic survival. by Kenneth Agerlin Halberg (503857)

“…Incubating tardigrades in phalloidin (P→W) did not decrease survival at 0.01 mg/ml (97 ± 7 %), 0.1 mg/ml (96 ± 4 %) and 0.5 (95 ± 5 %) mg/ml. …”

Arterial contractility 18 hours after CASP. by Stefan Felix Ehrentraut (136865)

“…<p><b>A</b> A significant hypocontractility of aortic rings in CASP- WT animals, but not in sham-operated WT animals was observed at phenylephrine concentrations of 10^−7,5 to 10⁻⁵M. …”

Quantification of signal intensities of co-purified candidate proteins of healthy and FIC diseased cases. by Gudrun Treutlein (295780)

“…Thioredoxin (D) is significantly (***p≤0.001) increased by a factor of 7.5 in FIC compared to urine of controls. …”

Non-searching strategies in the Morris water maze test. by Glòria Arqué (51650)

“…<p>Floating behavior (A and B) was operationally defined as any period equal to or longer than 5 s, during which the average mouse swimming speed stayed below 3 cm.s⁻¹. …”

Change in the expression of epithelial and mesenchymal cell markers after GSI IX treatment in human cholangiocarcinoma. by Mona El Khatib (127219)

“…<p>(A) SZ1 and (B) TFK1 cells were treated with control (DMSO) and GSI (5 µM, 20 µM and 40 µM) for 48 h and 96 h. …”

Phenotype of P63 knockdown zebrafish at 7dpf. by Hao Chen (5190)

“…(E) Normal ESQE. (F) Defective ESQE in a P63 knockdown zebrafish. (G) RT-PCR for P63 shows the un-spliced P63 transcript in MO injected zebrafish at 3, 5 and 7dpf. …”

Incidence of invasive pneumococcal disease by age category and year, South Africa, 2003–2008 (n = 17 604). by Susan Meiring (812550)

“…<p>Footnote: Between 2003 and 2004 there was a significant increase in disease (p<0.001), most notably in the 20–49 year age group (p<0.001), however from 2005 to 2008 disease incidence did not change significantly overall, however a small decrease was noted in the 5–19 year age group (p = 0.004).…”

The effects of pretreatment with fingolimod-phosphate on BMECs in the presence of MS sera. by Hideaki Nishihara (545149)

“…Pretreatment with fingolimod-phosphate resulted in an increase in the claudin-5 protein levels (B) and TEER values (G) and a decrease in the VCAM-1 protein levels (F) in the BMECs, which were upregulated after exposure to the sera from all MS patients, including the RRMS-R, RRMS-S and SPMS patients, compared to that observed in the cells not pretreated with fingolimod-phosphate.…”

Fure 4. CtBP2 expression in IHCs. by Patrick J. Atkinson (293860)

“…<p>(A) There was a significant decrease in the percentage of HCs that were positive for CtBP2 puncta after four days of deafness and after treatment with ATOH1 when compared to the normal hearing cochlea (*p<0.05, one way ANOVA). …”

Evaluations of entropy mapping using fMRI. by Ze Wang (132986)

“…<p>A) image of a cylinder water phantom; B) entropy map of the phantom. …”

Excitatory transmission onto LA principal cells of <i>Gdi1</i>-null mice. by Veronica Bianchi (186711)

“…(<b>C₁</b>) Spontaneous EPSC (Ctrl) and miniature EPSC (TTX) in both genotypes. Scale bars: 5 pA and 10 msec. (<b>C₂</b>) Mean EPSC values for each conditions. …”

Cdc42 depletion does not alter fibrillar actin content. by Romain Ferru-Clément (701878)

“…<p>RNAi-mediated depletions of Cdc42 or N-WASP were performed for 48 h and F-actin content was quantified as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0118943#pone.0118943.g005" target="_blank">Fig. 5</a> legend. …”

Alterations in the levels of total O-GlcNAc modified proteins and p53 in retinal PC incubated with DON and Alloxan for 16 by Zafer Gurel (558017)

“…</b> Protein lysates (50 µg) from retinal PC were analyzed by Western blot analysis for O-GlcNAcylated proteins and p53 (A). All treatments applied with 5 mM glucose in medium. …”

Heterogeneity of PTGDR mRNA expression levels in laser microdissected adenoma and tumor samples. by Sándor Spisák (123726)

“…Genes were considered to be downregulated with values lower than 0.5 (50% decrease, horizontal dotted line) (A) Expression value distribution of the 215894_at probeset (for <i>PTGDR</i> gene) in the GSE8671 (B) and GSE18105 (C) GEO data sets. …”