Localization of key HH signaling proteins is impaired in <i>Ttbk2</i>^{<i>sca11/gt</i>} cilia. by Emily Bowie (543704)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

Shortening of mTL anticipates accumulation of DDR markers, decrease in cell proliferation and increase in apoptotis with age. by Madalena C. Carneiro (102302)

“…All tissues show a significant increase in cells bearing five or more γH2AX foci by 12 months of age in <i>tert</i>^-/- zebrafish (panels b, d) and by 36 months in WT zebrafish (panels a, c and e). …”

Hypergravity Provokes a Temporary Reduction in CD4+CD8+ Thymocyte Number and a Persistent Decrease in Medullary Thymic Epithelial Cell Frequency in Mice by Ryosuke Tateishi (135017)

The decrease of similarity between the displacement of the center of pressure (COP) and the gaze point inhibited the displacement of the COP. by Hikaru Nakahara (13955347)

Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation by Elias Gounaris (52393)

“…Here we report that Zileuton, a specific 5-LO inhibitor, can prevent polyp formation by efficiently reducing the tumor-associated and systemic inflammation in APC^Δ468 mice.…”

Non-hydrolysable ATP analogues prevent decrease of I_Ca,L by metabolic inhibition. by Giedrius Kanaporis (4405525)

HPLC replicates of DAM-1 as standard and comparison view of DAM-1, <i>E</i>.<i>coli</i> + DAM-1 and solvent blank. by Manoj Limbraj Yellurkar (11467219)

Total number of hippocampal microRNAs that are increased or decreased after SE at each time point. by Rashmi M. Risbud (290321)

An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

<i>Becn1</i>^FA/FA mutation ameliorates cerebral Aβ accumulation, memory deficits and mortality of Alzheimer’s mouse models. by Altea Rocchi (3278457)

Mechlorethamine gel causes epithelium thinning, epithelium-stroma separation, and decreased total stroma cell count. by Ana M. Sandoval-Castellanos (11611315)

“…<p>A) Epithelium thickness decreased, and B) the percentage of epithelium-stroma separation increased after NM exposure. …”

Supplementary Material for: TNFAIP2 Inhibits Early TNFa-Induced NF-κB Signaling and Decreases Survival in Septic Shock Patients by Thair S.A. (4152325)

Tonic nM DA stabilizes the timing of LP activity over the short term. by Wulf-Dieter C. Krenz (693267)

“…<b>(B) The timing of LP activity is stabilized by 5nM DA</b>. In order to visually compare the timing of LP activity at t = 0,1min and 20min, we performed the following manipulations on each the two sets of traces shown in panel A. …”

The knockdown of p38MAPK and reduction of erythroid differentiation decreased K562 cell sensitivity to imatinib. by Yueh-Lun Lee (403469)

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in S4 Table) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE.... by Michael J. Johnson (5818168)

“…<p>Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1013759#ppat.1013759.s004" target="_blank">S4 Table</a>) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE. …”

MTP activity inhibition decreases HCV envelope glycoprotein secretion by E1E2-HepG2 and E1E2-Huh-7.5. by Vinca Icard (374872)

The MTT assay to determine decreases in residual cell viability in SK-N-BE2 and IMR-32 cells. by Nishant Mohan (474067)

“…As presented in the bar diagrams, combination of 50 nM LC3 shRNA plasmid and 25 µM GST in SK-N-BE2 cells while combination of 100 nM LC3 shRNA plasmid and 25 µM GST in IMR-32 cells showed the best synergistic efficacy, as determined by the combination index (CI) value, for the highest decrease in residual cell viability. …”

Tacrolimus decreased SFRP2 induced nuclear NFATc3 in 2H11 endothelial cells. by Sharareh Siamakpour-Reihani (218652)