Circumvallate papilla structure is retained but taste buds are lost with conditional Gli2 deletion. by Alexandre N. Ermilov (3365972)

“…CV depth and wall length did not change across time points in <i>Gli2cKO</i> tongues (E). Profile measures, used to indicate cell collections, were decreased by 28 days after <i>Gli2</i> gene deletion (F) and TB pore measures, to indicate complete TBs, also decreased (F). …”

Data_Sheet_1_Evaluation of the Efficacy and Safety of Switching to Pasireotide in Patients With Acromegaly Inadequately Controlled With First-Generation Somatostatin Analogs.pdf by Mônica Gadelha (3431090)

“…</p><p>Methods: Adults with uncontrolled acromegaly (mean GH [mGH] ≥1 μg/L from a five-point profile over 2 h, and IGF-I >1.3× upper limit of normal [ULN]) despite ≥3 months' treatment with maximal approved doses of long-acting octreotide/lanreotide received open-label long-acting pasireotide 40 mg/28 days. …”

Table_1_Enhanced immune reconstitution with albuvirtide in HIV-infected immunological non-responders.docx by Lina Fan (2211169)

“…</p>Methods<p>In this prospective, open-label, controlled clinical study, participants with incomplete immune reconstitution (continuous ART over 5 years and CD4⁺T lymphocyte absolute count of <500 cells/µl or ART for 2–5 years and CD4⁺T cell count of <200 cells/µl with undetectable viral load) were received intensive treatment with ABT or maintained on the original ART regimen at a ratio of 1:1. …”

DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters by Tuan M. Pham (16942388)

“…We show that <i>in silico</i> design of DNA secondary structures is improved by extending the base pairing alphabet beyond A–T and G–C to include the pair between 2-amino-8-(1′-β-d-2′-deoxyribofuranosyl)-imidazo-[1,2-<i>a</i>]-1,3,5-triazin-(8<i>H</i>)-4-one and 6-amino-3-(1′-β-d-2′-deoxyribofuranosyl)-5-nitro-(1<i>H</i>)-pyridin-2-one, abbreviated as <b>P</b> and <b>Z</b>. …”

DataSheet_1_Altered extracellular matrix correlates with an immunosuppressive tumor microenvironment and disease progression in younger adults with oral cavity squamous cell carcin... by Leonard E. Estephan (18844177)

“…Young patient TMEs demonstrated a 2.5-fold reduction in CD8⁺ T-cells as compared to older patients (p < 0.05).…”

Quantitative proteomics analysis. by Laura Piel (12251419)

“…<p>(A) Box plots representing the median ratio and the upper and lower quartiles of the LFQ intensity values for all LP biological replicates (LP.2, LP.3, LP.4 and LP.5) compared to the median of all EP replicates (EP.2, EP.3, EP.4 and EP.5). …”

Table_2_Influence of Drying and Wildfire on Longitudinal Chemistry Patterns and Processes of Intermittent Streams.DOCX by Ruth B. MacNeille (9912051)

Efficacy of Topical Cyclosporine Combined with Punctal Plugs in Treating Dry Eye Disease and Inflammation by Changming Feng (19810956)

Whole Transcriptome Analysis of <i>Acinetobacter</i><i> baumannii</i> Assessed by RNA-Sequencing Reveals Different mRNA Expression Profiles in Biofilm Compared to Planktonic Cells by Soraya Rumbo-Feal (309518)

“…Disruption or deletion of five of these genes caused a significant decrease in biofilm formation ability in the corresponding mutant strains. …”

<i>CasBurs α</i> and <i>ß</i> expressions in TGCs and CasBurs, CCAP and CHH protein contents in TGCs, POs and hemolymph during the molt cycle. by J. Sook Chung (130997)

“…Note that significant increases of CHH titers are already beginning during early to mid (E_10%–E_50%) and late (E_100%) ecdysis as indicated by lower case letters at <i>P</i><0.05 (ANOVA, Turkey-Kramer multiple comparison test). …”

Effective degradation of RPOA-2 by the AID system. by Qiuxia Zhao (9854718)

“…The depletion of RPOA-2, GRWD-1, or TSR-2 by the AID system caused a dramatic decrease of ribosomes and polysomes. The underlying data for (C-E) can be found in Tab I in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002276#pbio.3002276.s020" target="_blank">S1 Data</a>.…”

Silencing HK2 inhibits glioma cell invasion, migration, and proliferation <i>in vitro</i> and tumorigenesis <i>in vivo</i>. by Hui Liu (33624)

“…The rate of cellular migration was significantly decreased in both the HK2-silenced cell lines. (D-E). …”

Figshare20240613.pdf. Data obtained by American Heart Association Transformational Project Grant, 19TPA34850170.Update by Shinichi Oka (18824293)

“…The numbers of mice examined in each experimental group were: 6 (A), 6-7 (B), 7(C), 8 (D), 7 (acetyl lysine, E), 6-8 (acetyl-RelA at K310, E), 5 (acetyl lysine, F) and 6-8 (acetyl-RelA at K310, E). …”

Structural and Functional Models for the Dinuclear Copper Active Site in Catechol Oxidases:  Syntheses, X-ray Crystal Structures, Magnetic and Spectral Properties, and X-ray Absorp... by Frank Zippel (2971107)

“…These measurements reveal the reduction of Cu(II) to Cu(I) accompanied by a decrease of the coordination number.…”

Evolutionary history of deuterostome chromosome architectures. by Che-Yi Lin (218292)

“…<p>(<b>a</b>, <b>b</b>) A schematic representation of chromosome evolution in deuterostome lineages. …”

Clinical outcomes. by Yuta Seko (5703503)

“…We defined the weight loss as ≥ 5% decrease in body weight from discharge to 6-month index visit.…”

Data_Sheet_1_Multimodal Optical Imaging to Investigate Spatiotemporal Changes in Cerebrovascular Function in AUDA Treatment of Acute Ischemic Stroke.docx by Han-Lin Wang (8638884)

“…Moreover, at post-stroke day 3, increased functional vascular density was observed in AUDA-treated rats (35.9 ± 1.9% higher than that in the control group, p < 0.05). At post-stroke day 7, a 105.4% ± 16.4% increase of astrocytes (p < 0.01), 30.0 ± 10.9% increase of neurons (p < 0.01), and 65.5 ± 15.0% decrease of microglia (p < 0.01) were observed in the penumbra region in AUDA-treated rats (N = 5 for each group). …”

Extensive Natural Variation for Cellular Hydrogen Peroxide Release Is Genetically Controlled by Homa Attar (138799)

“…We did not find replication of SNPs across all cohorts, but replication within the same genomic region. Finally, a highly significant decrease in H₂O₂ release was observed in Down Syndrome (DS) individuals (p<2.88×10−12). …”

Data_Sheet_1_Variation of the BrO/SO2 Molar Ratio in the Plume of Tungurahua Volcano Between 2007 and 2017 and Its Relationship to Volcanic Activity.PDF by Simon Warnach (6901565)

“…For five phases, we additionally observe a progressive decrease to the initial values of 2 to 5 × 10⁻⁵ toward the end of the phase. …”

Heat Map Profiles of Serum miRNA Expression in Response to LPS Treatment. by Marjory B. Brooks (3636553)