Development of a Rapidly Dissolvable Oral Pediatric Formulation for Mefloquine Using Liposomes by Wei-Lun Tang (4014314)

“…The dosage form for Mef is mostly available as adult tablets, and thus children under the age of 5 suffer from poor medication adherence. We have developed a stable, rapidly dissolvable, and palatable pediatric formulation for Mef using liposomes composed of 1,2-distearoyl-<i>sn</i>-glycero-3-phosphocholine (DSPC) and cholesterol with a mean diameter of ∼110 nm. …”

Table_1_Triglyceride affects the association between estimated glomerular filtration rate and the onset of non-alcoholic fatty liver disease: A second analysis of a Chinese cohort... by Haofei Hu (8534712)

“…Further, compared to non-HTG subjects with eGFR ≥ 116.56 ml/min/1.73 m², participants with HTG and eGFR < 82.88 ml/min/1.73 m² had about a fourfold increase in the risk (HR = 4.852 95% CI: 3.943–5.970) of NAFLD.…”

Use of quantitative proteomics identifies a putative TvROM1 substrate. by Angelica M. Riestra (838706)

“…<b>(C)</b> The predicted TM domains of the five putative substrates identified in <b>A</b>, and the percent decrease in protein levels with 3,4-DCI <i>vs</i>. …”

Lymphatic density (LD; a) and blood vessel density (BD; b) in the myocardium by Y Ishikawa (46340)

“…The values of BD are 2693.4 ± 197.0 in Normal, 1689.9 ± 640.7 in Stage I, 571.4 ± 478.3 in Stage II, 51.8 ± 30.5 in Stage III, 1430.8 ± 323.1 in Stage IV, 1292.7 ± 153.1 in Stage V, 509.9 ± 276.3 in Stage VI and 130.5 ± 83.8 in Stage VII. …”

Interpretation on the model parameters. by Alexandre Blake (3837595)

“…<div><p>Cholera is a bacterial water-borne diarrheal disease transmitted via the fecal-oral route that causes high morbidity in sub-Saharan Africa and Asia. …”

Morphological changes caused by the lateral compression. by Heidi Peussa (12769831)

“…(D) Orthogonal projections of the actin chromobody-mCherry expressing MCDK II cell layer at different time points showing packing and thickening of the cells (scale bar 30 μm, inverted gray scale LUT), and (E) corresponding cell layer thicknesses during compression. …”

Supplementary Data 8 from Blockade of a Laminin-411–Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk by Tao Sun (91038)

CB2R inhibits NLRP3 inflammasome activation and augments autophagy in colon from DSS-induced colitis mice. by Ping Ke (3110763)

DataSheet1_Quantification of CYP3A and Drug Transporters Activity in Healthy Young, Healthy Elderly and Chronic Kidney Disease Elderly Patients by a Microdose Cocktail Approach.pdf by Punyabhorn Rattanacheeworn (11447329)

“…AUC and C_max GMR (95%CI) of atorvastatin, another CYP3A substrate, was increased 2.14 (1.52–3.02) fold in healthy elderly and 4.15 (2.98–5.79) fold in elderly patients with CKD, indicating decreased CYP3A activity related to ageing. …”

IRE1 silencing downregulates cell cycle genes and engages TP53 and specific CDK inhibitors. by Iratxe Zuazo-Gaztelu (21071939)

Mitochondrial membrane potential and ATP levels were reduced more by combination therapy than by single treatments of SLCP or BBR in U-87MG and U-251MG cells. by Panchanan Maiti (1459852)

Quantifying the Contribution of the Dispersion Interaction and Hydrogen Bonding to the Anisotropic Elastic Properties of Chitin and Chitosan by Pan Chen (385477)

“…Switching off the dispersion correction led to a decrease in modulus by up to 63%, depending on the direction. …”

Incidence, trends, and outcomes of infection sites among hospitalizations of sepsis: A nationwide study by Eric H. Chou (8293107)

“…Mortality from all sites of infection has decreased significantly (trend p<0.001). Skin and skin structure infection had the fastest declining rate (annual decrease: 5.5%) followed by primary bacteremia (annual decrease: 5.3%) and catheter related bloodstream infection (annual decrease: 4.8%).…”

Three decades of reference evapotranspiration estimates for a tropical watershed in the eastern Amazon by RENATO O. DA SILVA JÚNIOR (4629316)

Supplementary Material for: S100A8/A9 (Calprotectin), Interleukin-6, and C-Reactive Protein in Obesity and Diabetes before and after Roux-en-Y Gastric Bypass Surgery by Lylloff L. (4391575)

Dipeptidyl peptidase 4-inhibitor treatment was associated with a reduced incidence of neoplasm in patients with type 2 diabetes: a meta-analysis of 115 randomized controlled trials... by Zonglin Li (9229692)

In vitro BACE-activity assay on palAPP-dimers in detergent resistant membranes (DRMs). by Raja Bhattacharyya (3359186)

NET PRIMARY PRODUCTIVITY OF A MOUNTAIN FOREST ECOSYSTEM AS AFFECTED BY CLIMATE AND TOPOGRAPHY by Bayram Cemil Bilgili (10397591)

CB2R augments autophagy in peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

DataSheet_1_Icanbelimod (CBP-307), a next-generation Sphingosine-1-phosphate receptor modulator, in healthy men: pharmacokinetics, pharmacodynamics, safety, and tolerability in a r... by Jason Lickliter (18073228)

“…After single-dose 0.5 mg, although a high-fat breakfast versus fasting did not affect maximal decrease, lymphocyte counts tended to be lower after breakfast across most timepoints up to 72 hours. …”