Polyunsaturated fatty acid synthesis de novo is required for calcium release in vascular smooth muscle by Nicola Irvine (591917)

“…<p>Previous studies show that inhibition of delta-5 desaturase and delta-6 causes a<br>decrease in phenylepherine (PE)- induced vasoconstriction in human femoral artery,<br>and in rat aorta and mesenteric arteries. …”

Spontaneous mitotic recombination depends on normal CTD phosphorylation. by Tiffany Sabin Winsor (403023)

“…Deletion of <i>CTK1</i> causes a 5–20 fold decrease in recombination rates at three different heteroalleles.…”

Comparison of substrate metabolism in brown and white preadipocytes and adipocytes. by Barry R. Bochner (226699)

“…<p>Normalized optical-density scores representing nutrient metabolism, showing the greatest differences between white fat (top) and brown fat (bottom) cells in either an undifferentiated (gray bars) or differentiated (black bars) state. Included are a) wells that cause no change (1, negative control), b) nutrients that are high in brown preadipocytes and decrease upon differentiation (2, α-D-glucose-1-phosphate; 3, D-glucose-6-phosphate; 4, D-fructose-6-phosphate; 5, glycogen), c) a similarly behaved nutrient that is high in white fat (6, hexanoic acid), d) nutrients that decrease during differentiation of both cell types (7, dextrin; 8, butyric acid), and e) nutrients that increase upon white fat differentiation (9, L-leucine; 10, Leu-Leu; 11, succinamic acid, 12. acetoacetic acid). …”

Antihyperglycemic and neuroprotective effects of Wattakaka volubilis (L.f.) Stapf root against streptozotocin induced diabetes by Hajira Banu Haroon (12847493)

“…All the alcohol extract treated animals, showed a significant decrease in serum glucose level (P<0.001), and overall decrease in the severity of diabetic neuropathy. …”

DataSheet1_The effect of transcutaneous electrical stimulation of the submental area on the cardiorespiratory response in normal and awake subjects.docx by Abdulaziz Alsharifi (14786368)

“…A three-way ANOVA indicated that BP decreased significantly with TES (systolic: p = 4.93E-06, diastolic: p = 3.48E-09, mean: p = 3.88E-08). …”

Effect of amikacin-humic acid combination on <i>Acinetobacter baumannii</i> biofilm: an <i>in vitro</i> and <i>in silico</i> study by Seetha Lakshmi Rajangam (19921021)

CD11b⁺ CD11c^high cell activation during <i>L</i>. <i>infantum</i> infection is enhanced in TLR4-deficient mice. by Laís Amorim Sacramento (8623041)

“…(G) Venn diagram of transcripts showing a 2-fold increase or decrease in expression. The data are expressed as the means ± SEMs (n = 4 mice in A-D; BMDCs assessed in quadruplicate in E) and are representative of three independent experiments. …”

DataSheet_1_Including Volume Effects in Biological Treatment Plan Optimization for Carbon Ion Therapy: Generalized Equivalent Uniform Dose-Based Objective in TRiP98.pdf by Marco Battestini (12268814)

“…In particular, for a plan containing multiple OARs, we obtained the same target coverage and similar DVHs for OARs with a small volume effect while decreasing the mean dose received by the proximal parotid, thus reducing its NTCP by a factor of 2.5. …”

Diffusive dynamics of white player’s advantage. by Haroldo V. Ribeiro (277883)

Data_Sheet_1_Concerted suppressive effects of carisbamate, an anti-epileptic alkyl-carbamate drug, on voltage-gated Na+ and hyperpolarization-activated cation currents.docx by Te-Yu Hung (15861305)

“…However, CRS strongly decreased the strength (i.e., Δarea) of the nonlinear window component of I_Na (I_Na(W)), which was activated by a short ascending ramp voltage (V_ramp); the subsequent addition of deltamethrin (DLT, 10 μM) counteracted the ability of CRS (100 μM, continuous exposure) to suppress I_Na(W). …”

Comparison of current amplitudes from mutant and WT mBest2 Cl⁻ channels. by Agata Kranjc (253149)

“…E306A had a mean value not significantly different from WT (P = 0.5; N = 7–8). …”

Stringency of the association of Vsp-recombinant <i>B. burgdorferi</i> clones with human brain endothelium. by Gaurav Gandhi (239145)

“…<p>HBMEC monolayers on transwell chambers that had been incubated with S35-labeled Vsp-recombinant clones of <i>B. burgdorferi</i> at 37°C and rinsed with media were washed with 250 mM NaCl PBS followed by lysis with 0.5% SDS in water (panel A). In some experiments we incubated B31-5A18NP1-Vsp1 with HBMEC also at 4°C (panel B). …”

Low salt project by Thananda Trakarnvanich (10066099)

“…The intervention group was provided a salt diet (1.5 gm/day) for 3 months. The control group consumed their usual diet; daily food intake was recorded. …”

Reduction in DRG neuronal numbers following error correction. by Ayal Ben-Zvi (438134)

“…A significant decrease in neuron number is observed in the Sema3A^−/−:BAX^−/− embryos as compared to Sema3A^+/+: BAX^−/−, which correlates with error correction (P = 0.0169). …”

Phenotypic analysis of <i>loh</i> mutants in response to hypoxic and ethanolic treatments. by Li-Juan Xie (474189)

“…The numbers in the columns correspond to seedlings with true leaves (1), seedling with green (2) or brown (3) cotyledons, etiolated seedlings (4) and not germinated seeds (5). (E) Decrease of fatty acyl unsaturated ceramides in <i>loh</i> mutants upon dark submergence treatment in comparison to wild type. …”

Ngn2 and NeuroD1 mark the initiation and end of amplification of hippocampal DG granule neuroblasts, respectively. by Laurent Roybon (266715)

“…Arrows and arrowheads point at cells of interest. Scale bars: 100 µm (B1, C1 and C2), 50 µm (A1, D1, E1, F1, G1, H1, I1, K and L1), 25 µm (A2, B2, and F2), 10 µm (L2), 5 µm (C3, E2, G2, H2 and I2).…”

<i>nDf59</i> enhancement of <i>lin-12</i> activity and the identification of <i>sel-11</i> as <i>hrd-1</i>. by Min Sung Choi (137920)

“…Expression of <i>mir-61/250</i> in P5.p and P7.p depends on LIN-12 activation, mediated by LAG-1 Binding Sites in the 5′ flanking region <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0011885#pone.0011885-Yoo1" target="_blank">[11]</a>. …”

Visual behavioral and transretinal ERG responses of PhLP1-deficient mice. by Christopher M. Tracy (690435)

“…The figure shows the match in the rising phase produced by this procedure. A 5.3-fold decrease in amplification constant in the <i>PhLP1</i>^<i>F/F</i> mice can be calculated from the ratio of the <i>PhLP1</i>^<i>F/F</i> to <i>PhLP1</i>^<i>+/+</i> light intensity after correction by the scaling factor. …”

Changes in cell elasticity from physiologic substrate rigidity and stretch modulate macrophage phagocytosis. by Naimish R. Patel (136156)

“…Differential interference contrast (DIC) microscopy images of RAW 264.7 macrophages cultured on a less rigid (<i>E</i> = 1.2 kPa) versus rigid (<i>E</i> = 150 kPa) polyacrylamide gel coated with poly-L-lysine to facilitate attachment. …”

Image_1_Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis.JPEG by Gerjan J. Dekkema (7375049)

“…Overexpression of miR-142-3p significantly decreased cAMP levels (p = 0.02) and tended to decrease the mRNA levels of a predicted target gene, adenylate cyclase 9 (ADCY9; p = 0.06). …”