Host cytosolic calcium increases prior to PV rupture. by My-Hang Huynh (20360)

“…A vertical line denotes the time point after which host Ca²⁺ levels increase and near when the PV pH decreases. …”

Changes of best-correct visual acuity, central retinal thickness, and subfoveal choroidal thickness among the 4 groups. by Mio Matsubara (8486133)

“…(B) Changes of central retinal thickness among the 4 groups. Mean central retinal thickness(CRT) significantly decreased from 350±100 μm at baseline to 177±33μm at 6-month, 178±31μm at 12-month, and 196±62μm at 24-month (p = 8.9×10⁻⁵, 8.9×10⁻⁵ and 2.5×10⁻⁴, respectively) in Group 0, mean CRT also significantly decreased from 475±77 μm at baseline to 205±23μm at 6-month, 197±24μm at 12-month, and 192±33μm at 24-month (p = 1.2×10⁻², 1.2×10⁻² and 1.2×10⁻², respectively) in Group 1, mean CRT significantly decreased from 400±104 μm at baseline to 207±60μm at 6-month, 221±75μm at 12-month, and 194±47μm at 24-month (p = 8.3×10⁻⁶, 3.3×10⁻⁵ and 9.3×10⁻⁶, respectively) in Group 2, and mean CRT decreased from 294±62 μm at baseline to 250±104μm at 6-month, 197±44μm at 12-month, and 238±74μm at 24-month (p = 0.25, 2.8×10⁻² and 5.8×10⁻², respectively) in Group 3. …”

Prevalence, Awareness, Treatment, and Control of Hypertension in United States Counties, 2001–2009 by Casey Olives (139016)

“…Over the last decade, national-levels of controlled hypertension have increased, but little information on hypertension prevalence and trends in hypertension treatment and control exists at the county-level. We estimate trends in prevalence, awareness, treatment, and control of hypertension in US counties using data from the National Health and Nutrition Examination Survey (NHANES) in five two-year waves from 1999–2008 including 26,349 adults aged 30 years and older and from the Behavioral Risk Factor Surveillance System (BRFSS) from 1997–2009 including 1,283,722 adults aged 30 years and older. …”

Action of anandamide (AEA, 400 µM) on planar lipid bilayers: effect of cholesterol. by Eric Di Pasquale (373571)

“…<p><i>A–B</i>. superimposed currents across a bilayer constituted of POPC alone (<i>A</i>), held at 0 mV, in response to a rectangular pulse (+180 mV, 200 ms), before (control, light grey bilayer alone), and after addition of anandamide (heavy grey, +5, +25 min after AEA injection). …”

Spliceosomal particle formation depends on NPC count. by Zhaleh Ghaemi (1507558)

“…<p>Increase (pink) or decrease (blue) in the number NPCs by 20% results in a corresponding change in the number of U1 (A) and U2 (B) particles formed. …”

Destabilization of dystrophin and β-DG by Lis1-Nde1 deficiency. by Ashley S. Pawlisz (52227)

“…<p>(A) Total protein extracts from cerebral cortices of E12.5 embryos were examined by immunoblotting. …”

Dose-related neflamapimod (NFMD) subacute treatment effects on mNSS of rats with tMCAO. by John J. Alam (9732692)

“…In addition, a dose response effect on improvement in neurologic function was indicated by the lower mean±SD mNSS value in the 4.5 mg/kg neflamapimod dose group when compared to that of the 1.5 mg/kg dose group. …”

Raw rachis data: Raw rachis morphological and structural properties used in our analysis from Rachis morphology cannot accurately predict the mechanical performance of primary feat... by John Lees (359812)

“…Intraspecifically, both <i>E</i>_bend and <i>M</i>_max were strongly correlated with morphology, decreasing and increasing, respectively, with all three morphological measures. …”

Citalopram does not increase neural signals for reward or effort outcomes. by Jacqueline Scholl (3752851)

“…On the contrary, a more lenient time point—by—time point <i>t</i> test analysis of the time courses revealed that in striatum and vmPFC, citalopram, in fact, decreased the relative reward magnitude outcome signal late in the outcome phase (*<i>p</i> < 0.05 for time point—by—time point two-sided <i>t</i> tests). …”

Statistical description of the activity in excitatory-inhibitory networks with external and spiking noise. by Francesca Mastrogiuseppe (3947603)

“…Increasing the time constant of rate dynamics (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005498#pcbi.1005498.e079" target="_blank">Eq (50)</a> in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005498#sec019" target="_blank">Methods</a>) decreases the amplitude of spiking noise. …”

Regulation of targets by EWS in vivo. by Sujitha Duggimpudi (699551)

“…The linear regression and slopes were calculated and the data is presented as Mean and SEM on a linear scale. <b>E</b>. Luciferase activity of CCDC6 upon EWS transfection (normalized to empty psiCHECK-2 plasmid). …”

Line3-2 reveals lung hypoplasia and limb syndactyly. by Carsten Schnatwinkel (48)

“…<p>(A–H) Embryos dissected at E18.5 (A) reveal that line3-2 mutants are slightly reduced in size and have significantly smaller lung lobes (B–F). …”

Comparative Component Analysis of Exons with Different Splicing Frequencies by Shiqin Song (264631)

“…Beyond the conventional classification for alternatively spliced exons (ASEs) and constitutively spliced exons (CSEs), we have classified exons from alternatively spliced human genes and their mouse orthologs (12,314 and 5,464, respectively) into four types based on their splicing frequencies. …”

The Essential Nucleolar Yeast Protein Nop8p Controls the Exosome Function during 60S Ribosomal Subunit Maturation by Marcia C. T. Santos (215784)

“…Although depletion of Nop8p in yeast cells leads to premature degradation of rRNAs, the biochemical mechanism responsible for this phenotype is still not known. In this work, we show that the Nop8p amino-terminal region mediates interaction with the 5.8S rRNA, while its carboxyl-terminal portion interacts with Nip7p and can partially complement the growth defect of the conditional mutant strain <em>Δnop8/GAL::NOP8</em>. …”

Competition of SP-D binding to gp120 by hexoses. by Jens Madsen (391091)

“…Each trace indicates the response units recorded at a given concentration of SP-D (10, 5, 2.5, 1.25, and 0.625 µg/mL) in 5 mM CaCl₂-containing (HSC) buffer (traces are in order of the highest to lowest concentration). …”

Weight loss following gastric bypass increases aldosterone reactivity to orthostatic stress in patients with obesity by Joachim Zahnd (22169617)

“…At 12 months, mean weight decreased from 126.3 ± 23.2 kg to 116 ± 20.7 kg in the control group and from 120.9 ± 19.4 kg to 78.6 ± 14.0 kg in the RYGB group (<i>p</i> value < 0.01 between groups). …”

Blood Pressure Modifies Retinal Susceptibility to Intraocular Pressure Elevation by Zheng He (137369)

“…Elevated intraocular pressure (IOP) is a risk factor for glaucoma and may reduce nutrient availability by decreasing ocular perfusion pressure (OPP). …”

Data_Sheet_1_Association of Gut Microbiota With Metabolism in Rainbow Trout Under Acute Heat Stress.docx by Changqing Zhou (175208)

“…In the current study, the optimal growth temperature (16°C) of rainbow trout was used as the control group, while the fish treated at 22.5°C, 23.5°C, and 24.5°C for 24 h, respectively, were the treatment groups. …”

The effect of mycophenolic acid (MPA) and guanosine (Gua) on HCV infectious progeny production and intracellular nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…<p>(a) Huh-7.5 reporter cells were infected with HCVp0 at an initial MOI of 0.1–0.2 TCID₅₀/cell, in the absence or presence of the MPA and Gua concentrations indicated in the upper box. …”

DataSheet_1_Vessel sound causes hearing loss for hummingbird bobtail squid (Euprymna berryi).pdf by Rosalyn L. Putland (5814887)

“…Baseline audiograms indicated that there was a decrease in aural sensitivity with age. All three age groups showed similar, significantly decreased hearing sensitivity following sound exposure, however auditory sensitivity recovered within two hours. …”