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67641
Table_3_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.XLSX
Published 2019“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”
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67642
Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases
Published 2023“…Moreover the expression levels of sEH, COX-2, NOS-2, vascular cell adhesion molecule (VCAM), IL-6, MCP-5, and tumor necrosis factor α (TNF-α) were measured by Western blot or enzyme-linked immunosorbent assay (ELISA), with varying degrees of decrease. …”
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67643
Table_1_The burden of testicular cancer from 1990 to 2019 in the Middle East and North Africa region.docx
Published 2023“…During the period 1990 to 2019, the age-standardized DALY rate of testicular cancer steadily rose with higher SDI values, except for a decrease observed at an SDI of 0.8.</p>Conclusion<p>Over the last thirty years, there has been a notable rise in the burden of testicular cancer in the MENA region.…”
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67644
Table_1_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.XLSX
Published 2019“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”
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67645
Data_Sheet_1_In vitro antimicrobial activity and resistance mechanisms of the new generation tetracycline agents, eravacycline, omadacycline, and tigecycline against clinical Staph...
Published 2022“…After treatment with eravacycline, omadacycline or tigecycline, overexpression of mepA, tet38, tet(K) and tet(L) was detected. Moreover, multi-locus sequence typing showed a major clonal dissemination type, ST5, and its variant ST764 were seen in most tetracyclines-resistant strains. …”
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67646
Table4_Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells.DOCX
Published 2022“…Increases (≥two-fold) were also observed in levels of Wnt signaling regulator (glypican-4), actin-binding chromatin modulator (BRG1) and nuclear actin filament depolymerizing protein (MICAL2; microtubule-associated monooxygenase, calponin and LIM domain containing), together with a decrease in tissue plasminogen activator. These changes were independently further confirmed by immunoblotting analysis. …”
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67647
Image2.TIF
Published 2018“…Moreover, the photocatalytic activity of 30%BiOI/BiOCl had no obvious decrease after five recycles, suggesting that it was a promising photocatalyst for the removal of MB and RhB pollutants. …”
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67648
Inclusion of evolutionary information greatly increases the specificity and selectivity of CRM searches based on binding-site clustering
Published 2011“…The number of false positives is not strictly monotonically decreasing with an increasing binding site cutoff. This stems from the cluster merging behavior of CIS-ANALYST - sometimes a decrease in the minimum number of sites leads CIS-ANALYST to tack on a lower-density cluster that is adjacent to a higher-density one, resulting in a single cluster with more sites but lower site density. …”
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67649
Soil chemical properties and nutrition of conilon coffee fertilized with molybdenum and nitrogen
Published 2022“…The experimental design used was in randomized blocks, in a 2 × 5 factorial scheme, the first factor being the absence and presence (4 kg ha-1 yr-1) of molybdic fertilization and the second factor was the N dose (300, 500, 700, 900, and 1,100 kg ha-1 yr-1). …”
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67650
Table_1_Non-isoflavones Diet Incurred Metabolic Modifications Induced by Constipation in Rats via Targeting Gut Microbiota.DOCX
Published 2018“…Following 16S rRNA compositional sequencing, results excluded the changes in intestinal microbiota over time and highlighted that a total of 5 phyla and 21 genera changed significantly, among which Firmicutes, Bacteroidetes, Blautia, Prevotella, Lactobacillus and Bifidobacterium were closely related to constipation. …”
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67651
Soluble plantain NSP increases the transmucosal short circuit current of <i>ex vivo</i> human ileal follicle-associated epithelium.
Published 2014“…<p>Plantain NSP (5 mg/mL) significantly increased (<b>A</b>) transmucosal short circuit current (<i>I<sub>sc</sub></i>), with a concomitant decrease in (<b>B</b>) epithelial potential difference (PD, apical-side negative), during pre-treatment of, and blockade of translocation of S. …”
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67652
Hydroxychloroquine in Stage 1 Type 1 Diabetes
Published 2023“…Preplanned secondary analyses showed a transient decrease in the glucose average area under the curve to oral glucose in the hydroxychloroquine-treated arm at month 6 and a reduced titer of anti-GAD and anti-insulin autoantibodies and acquisition of positive autoantibodies in the hydroxychloroquine arm (p=0.032).…”
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67653
Squirrels Experiment
Published 2014“…Each area would be split into quadrants using a map and certain areas would be observed. Recordings of: number of squirrels, overall crowdedness (scale from 1-5) and presence of other animals would be noted and recorded for each area. …”
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67654
DataSheet_4_Natal environmental conditions modulate senescence of antler length in roe deer.zip
Published 2023“…We found evidence of similar patterns of antler length senescence in both populations, with an onset of senescence around 7 years of age and a decrease of length by about 1–1.5 cm per additional year of life from 7 years of age onwards. …”
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67655
Crop-Specific Emission Projection Suggests Peaking of Agricultural N<sub>2</sub>O by the Middle Century
Published 2024“…Our findings show that global agricultural N<sub>2</sub>O emissions will peak around 2065, ranging from 5.2 to 6.6 Tg N a<sup>–1</sup>. Corn cultivation is the primary N<sub>2</sub>O contributor, while rice production will produce fewer emissions and peak before 2025. …”
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67656
Chronic neuronal activity inhibition by TTX reduces extracellular amyloid in APP<sup>Swe</sup>/PS1<sup>L166P</sup> mice.
Published 2013“…The analysis showed an increase of plaque number (<b>A</b>; <b>C</b>) but not of plaque size (<b>B</b>; <b>D</b>) after TTX administration in hippocampus (<b>A</b>; <b>B</b>) and entorhinal cortex (<b>C</b>; <b>D</b>) (n = 5 in each group, three sections per mouse, three frames per section, <i>* P</i><0.05, *** <i>P</i><0.001, Student’s <i>t</i>-test). …”
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67657
DataSheet_1_Neuroprotective Effects of Qingnao Dripping Pills Against Cerebral Ischemia via Inhibiting NLRP3 Inflammasome Signaling Pathway: In Vivo and In Vitro.docx
Published 2020“…Further, we found that QNDP inhibited NLRP3 inflammasome expression both in MCAO rats and in SH-SY5Y cells under OGD. Moreover, the levels of inflammatory cytokines including interleukin-1β (IL-1β) and IL-18, which mediated by NLRP3 inflammasome and increased in MCAO rats, could be reduced by QNDP, suggesting that QNDP could protect the neurons against inflammation through a mechanism mediated by NLRP3 inflammasome. …”
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67658
Image_1_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.tif
Published 2024“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. …”
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67659
Ocular exposure to infectious laryngotracheitis virus alters leukocyte subsets in the head-associated lymphoid tissues and trachea of 6-week-old White Leghorn chickens
Published 2020“…In the HG, the most notable change in cells from ILTV-infected birds was a decrease in IgM expressing cells and histologically, an increase in Mott cells. …”
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67660
Table_4_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.xlsx
Published 2019“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”