Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…Here we utilize SILAC-based quantitative phosphoproteomics to analyze murine <i>FMR1</i>^– and <i>FMR1</i>⁺ fibroblastic cell lines derived from <i>FMR1</i>-KO embryos to identify proteins and phosphorylation sites dysregulated as a consequence of FMRP loss. We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…Here we utilize SILAC-based quantitative phosphoproteomics to analyze murine <i>FMR1</i>^– and <i>FMR1</i>⁺ fibroblastic cell lines derived from <i>FMR1</i>-KO embryos to identify proteins and phosphorylation sites dysregulated as a consequence of FMRP loss. We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Waste Cotton Fabric/Zinc Borate Composite Aerogel with Excellent Flame Retardancy by Qin Qin (83769)

“…A waste cotton fabric (WCF)/zinc borate (ZB) composite aerogel with flame resistance was successfully synthesized through zinc borate immobilized in the cellulose aerogel by in situ formation by dissolving a waste cotton fabric in NaOH/urea aqueous solution. …”

Effects of temperature and salinity on respiratory losses and the ratio of photosynthesis to respiration in representative Antarctic phytoplankton species by Deborah Bozzato (7522097)

“…In the comparison of phytoplankton grown at 1 and 4°C the rGP/R decreased from 11.5 to 7.7 in <i>Chaetoceros</i> sp., from 9.1 to 3.2 in <i>Phaeocystis antarctica</i> strain 109, and from 12.4 to 7.0 in <i>P</i>. …”

Treatment with the Proteasome Inhibitor MG132 during the End of Oocyte Maturation Improves Oocyte Competence for Development after Fertilization in Cattle by Jinyoung You (121636)

“…Another protein decreased by MG132, CDK5, can lead to apoptosis if aberrantly activated and one protein increased by MG132, P4HB, is anti-apoptotic. …”

L1 starvation activates AAK-2 partially depending on PAR-4, <i>C. elegans</i> LKB1. by Inhwan Lee (136973)

“…AAK-2 is phosphorylated in response to starvation and mitochondrial poisoning with NaN₃ in a partially PAR-4 dependent manner. Lane 1: wild type adults placed on unseeded NGM plates for 6 hours (control), Lane 2: wild type adults treated with 1 mM NaN₃ for 6 hours on unseeded NGM plates, Lane 3: <i>aak-2</i> mutants (<i>ok524</i>) treated with 1 mM NaN₃ for 6 hours, Lane 4: <i>par-4</i> mutants treated with 1 mM NaN₃ for 6 hours, Lane 5: wild type adults starved for 24 hours in M9, Lane 6: <i>aak-2</i> mutants (<i>ok524</i>) starved for 24 hours, Lane 7: <i>par-4</i> mutants starved for 24 hours. …”

DataSheet_2_Highlighting the novel effects of high-intensity interval training on some histopathological and molecular indices in the heart of type 2 diabetic rats.docx by Mohammad Rami (15650177)

“…This research showed that diabetes disorder increases the levels of B-catenin and c-Myc proteins and causes a decrease in the expression of GSK3B and Bcl-2 proteins. …”

DataSheet_1_Deep mowing rather than fire restrains grassland Miscanthus growth via affecting soil nutrient loss and microbial community redistribution.docx by Zhuxin Mao (12578495)

“…After harvest, deep mowing induced the greatest effect on biomass among all treatments, as it induced a 5.2-fold decrease in dry biomass relative to the control. …”

Dietary Lactic Acid Bacteria Modulate Yolk Components and Cholesterol Metabolism by Hmgr Pathway in Laying Hens by Q Deng (10447343)

“…In liver, high LAB downregulated (p<0.05) mRNA expression of serine/threonine kinase 11 (STK11), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), AMP-activated protein kinase catalytic subunit (PRKAA1, 2), and protein phosphatase catalytic subunits (PPP2CA, PPP2CB and PPP3CA) by 49.5 to 175.4%. …”

Image_1_Amelioration of cold-induced sweetening in potato by RNAi mediated silencing of StUGPase encoding UDP-glucose pyrophosphorylase.jpg by Sandeep Jaiswal (5214794)

“…The selected transgenic lines carried two to five copies of the transgene. Northern hybridization revealed an accumulation of siRNA with a concomitant decrease in the StUGPase transcript level in these selected transgenic lines. …”

Alleviation of Nanoplastic Stress in Rice: Evidence from Biochemical, Cytological, Physiological, and Transcriptome Analysis by Jiacheng Jin (11480055)

In vitro analysis of the segmental flexibility of the thoracic spine by Hans-Joachim Wilke (436691)

“…In our in vitro study, 68 human thoracic functional spinal units including the costovertebral joints (at least n = 6 functional spinal units per segment from T1-T2 to T11-T12) were loaded with pure moments of ±7.5 Nm in flexion/extension, lateral bending, and axial rotation in a custom-built spine tester to analyze range of motion (ROM) and neutral zone (NZ). …”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Moreover, our studies have excluded a role of complement in the skin accumulation of liposomes. …”

Dataset and README file for paper from Denarie et al. by Marie-Emma Denarié (22670696)

“…</p><p dir="ltr">3. We examined how a gradient of Si-defence in wheat affected relative growth rates (RGR) and mandible wear of <i>H. armigera</i>. …”

Table_1_L-Arginine abrogates maternal and pre-pubertal codeine exposure-induced impaired spermatogenesis and sperm quality by modulating the levels of mRNA encoding spermatogenic g... by Roland Eghoghosoa Akhigbe (13783261)

“…These perturbations were accompanied by a decrease in mRNA levels encoding spermatogenic genes, testicular testosterone and androgen receptor (AR) concentrations, and upregulation of sperm 8-hydroxydeoxyguanosine (8OHdG). …”

Conservation Efforts May Increase Malaria Burden in the Brazilian Amazon by Denis Valle (197557)

“…</p> <p>Methods and Findings</p><p>Using a large malaria dataset (∼1,300,000 positive malaria tests collected over ∼4.5 million km²), satellite imagery, permutation tests, and hierarchical Bayesian regressions, we show that greater forest cover (as a proxy for proximity to forest fringes) tends to be associated with higher malaria incidence, and that forest cover effect was 25 times greater than the land clearing effect, the often cited culprit of malaria in the region. …”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Moreover, our studies have excluded a role of complement in the skin accumulation of liposomes. …”

Graphical models of PCNA Ser46 and Leu47 residues are crucial in genomic integrity. by Sangin Kim (1458700)

“…<p>(A) During DNA replication, PCNA^WT forms a homotrimer and is loaded onto the lagging strand of DNA by the RFC. …”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Moreover, our studies have excluded a role of complement in the skin accumulation of liposomes. …”

Image1_HSP90 Inhibitor Ganetespib Enhances the Sensitivity of Mantle Cell Lymphoma to Bruton’s Tyrosine Kinase Inhibitor Ibrutinib.TIF by Ziwen Lu (6643010)

“…In this study, transient ganetespib treatment sensitizes MCL cells to ibrutinib as manifested by the significant decrease of IC₅₀ values, percentages of EdU (5-Ethynyl-2′-deoxyuridine) positive cells, and levels of p-AKT and NF-κB after combinational treatment. …”