hMSCs reduces proliferation of stimulated lymphocytes in a contact-independent manner. by Marilia Normanton (624970)

“…<p>(A–B) A significant proliferation reduction of PHA stimulated lymphocytes (CD3) (38.58±12.39%) assessed by expression of KI-67 was observed in presence of hMSCs (CD3: hMSC) (24.39±12.39%), the same was observed when absolute number KI-67 expressing cells was evaluated decreasing from (3.0×10⁵±1.3×10⁵) up to (1.7×10⁵±0.9×10⁵) (n = 8). …”

Image_1_Can nirmatrelvir/ritonavir treatment shorten the duration of COVID-19 isolation?.pdf by Haein Kim (4839594)

“…Background<p>The impact of nirmatrelvir/ritonavir treatment on shedding of viable virus in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear.</p>Methods<p>A prospective cohort study evaluating mildly ill COVID-19 patients was conducted. …”

Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis by Nathan R. Hill (802856)

“…We assessed pooled data using a random effects model. Of 5,842 potential articles, 100 studies of diverse quality were included, comprising 6,908,440 patients. …”

The WHO strategy for prevention and control of snakebite envenoming: a sub-Saharan Africa plan by Jean-Philippe Chippaux (790696)

Data_Sheet_1_Creation of a Low-Alcohol-Production Yeast by a Mutated SPT15 Transcription Regulator Triggers Transcriptional and Metabolic Changes During Wine Fermentation.PDF by Qing Du (1610224)

“…Here the global transcription machinery engineering (gTME) technology was used to engineer a yeast strain with decreased ethanol yield, based on the mutation of the SPT15 gene. …”

Supplementary Material for: A Novel Mutation in Insulin-Like Growth Factor 1 Receptor (c.641-2A>G) Is Associated with Impaired Growth, Hypoglycemia, and Modified Immune Phenotypes by Shapiro M.R. (9572729)

Clinicopathological features and postoperative prognosis of invasive mucinous adenocarcinoma: a retrospective study by Tengteng Wang (14288480)

“…However, 5-year overall survival of the IMA group was significantly decreased. …”

Autophagy mediates the inhibitory effect of CB2R on NLRP3 inflammasome initiation and activation stimulated with LPS/DSS <i>in vitro</i>. by Ping Ke (3110763)

“…<p>(A) The quantitative expression of mRNA in RAW264.7 cells after transfection with control siRNA or <i>Atg5</i> siRNAs. n = 6 per group. …”

CB2R inhibits the production of IL-1β but not IL-6 and TNF-α in cultured peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

Representative changes of tumor size and necrosis size with attenuation on first follow-up contrast-enhanced computed tomography (CT) scans in metastatic renal cell carcinoma (RCC)... by Sung Han Kim (512136)

“…<p>A. Axial CT image before sunitinib therapy showed a 14.5 cm-sized enhancing left renal mass with hilar invasion and presence of venous tumor thrombi. …”

DataSheet_1_The effect of G0S2 on insulin sensitivity: A proteomic analysis in a G0S2-overexpressed high-fat diet mouse model.pdf by Dongming Wu (11619167)

“…</p>Methods<p>In this study, we extracted livers from mice that consumed HFD and received tail vein injections of AD-G0S2/Ad-LacZ, and performed a proteomics analysis.</p>Results<p>Proteomic analysis revealed that there was a total of 125 differentially expressed proteins (DEPs) (56 increased and 69 decreased proteins) among the identified 3583 proteins. …”

Table 2_The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leish... by Raphael Taiwo Aruleba (12011345)

“…</p>Methods<p>BALB/c mice infected with L. donovani were divided into cured and non-cured groups based on treatment with a non-ionic surfactant vesicle formulation of sodium stibogluconate (300 mg Sb^v/kg, SSG-NIV) or PBS vehicle control. …”

Supplementary Material for: Ruyi Zhenbao Tablet and Baimai Ointment Therapy in Acute Ischemic Stroke: A Study Protocol for a Multi-center, Randomized, Double-blinded, and Parallel... by Qin X. (3237450)

Table 1_The effect of treatment with a non-ionic surfactant vesicular formulation of sodium stibogluconate on host immune responses and serum metabolites in a murine model of Leish... by Raphael Taiwo Aruleba (12011345)

“…</p>Methods<p>BALB/c mice infected with L. donovani were divided into cured and non-cured groups based on treatment with a non-ionic surfactant vesicle formulation of sodium stibogluconate (300 mg Sb^v/kg, SSG-NIV) or PBS vehicle control. …”

CB2R negatively regulates NLRP3 inflammasome activation in peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

10 μM βE2 pretreatment for 0.5 hrs protected primary cultured SD rat retinal cells from apoptosis induced by 100 μM H₂O₂ treatment for 24 hrs. by Yan Feng (128912)

“…<p>The PI3K/Akt pathway mediated this process, but the alteration in [Ca²⁺]_i was undetectable. A: The Annexin V/Propidium Iodide staining apoptosis assay; B: Quantitative data of A; C and D: Cell viability and [Ca²⁺]_i quantitative data; 10 μM βE2 pretreatment for 0.5 hrs significantly restored the decrease in cell viability and apoptosis, which was significantly inhibited by 10 μM LY (B, C), but the [Ca²⁺]_i was not significantly altered in all treated groups (D); E: Western blot results, 10 μM βE2 pretreatment for 0.5 hrs promoted p-Akt level, which was inhibited by 10 μM LY pretreatment for 0.5 hrs before βE2 and H₂O₂ co-treatment. …”

<i>KIR2DL2</i> in HCV infection: <i>KIR2DL2</i> enhances the protective effect of <i>HLA-B*57</i> on HCV status (spontaneous clearance v chronic infection) and, independently, on H... by Nafisa-Katrin Seich al Basatena (201133)

Risk of AVF-occlusion after surgery. by Clemens Grupp (7411073)

Influence of Ocean Acidification on a Natural Winter-to-Summer Plankton Succession: First Insights from a Long-Term Mesocosm Study Draw Attention to Periods of Low Nutrient Concent... by Lennart T. Bach (520701)

“…<div><p>Every year, the oceans absorb about 30% of anthropogenic carbon dioxide (CO₂) leading to a re-equilibration of the marine carbonate system and decreasing seawater pH. …”

DataSheet_1_Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy.docx by Saeid Najafi-Fard (13719727)

“…Here we investigated the impact of IL-10 in COVID-19, through the ex-vivo assessment of the effects of exogenous IL-10 on SARS-CoV-2-specific-response using a whole-blood platform.…”