A Systems Toxicology Approach to Elucidate the Mechanisms Involved in RDX Species-Specific Sensitivity by Christopher M. Warner (2064109)

“…We quantitatively examined the validity of interspecies uncertainty factors by comparing the responses of zebrafish (<i>Danio rerio</i>) and fathead minnow (<i>Pimephales promelas</i>) to the energetic compound 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), a known neurotoxicant. …”

A Novel Network Profiling Analysis Reveals System Changes in Epithelial-Mesenchymal Transition by Teppei Shimamura (133856)

“…As a result, we found that knockdown of KLF5 by siRNA significantly decreased E-cadherin expression and induced morphological changes characteristic of EMT. …”

Structure of the rDNA, LINE-1 and Alu units and localization of target regions assessed. by Fabio Marson (17283598)

ROS levels, cell viability, and LDH and Fe²⁺ content in HT22 cells after XMU-MP-1 treatment. by Lu Li (14069)

Blockade of Alk receptor activation abolishes neuronal differentiation due to Activin A treatment. by Griselda Rodríguez-Martínez (140821)

“…Addition of growth factors and inhibitors was made every other day. SB431542 (Alk4, Alk5 and Alk7 inhibitor, 5 µM), Follistatin (Activin A ligand-trap, 20 ng/ml) or Dorsomorphin (BMP antagonists, 5 µM) were added to NPC cultures 1 hour previous to Activin A. …”

<i>C</i>. <i>burnetii</i> reduces lysosomes independent of autophagy. by Dhritiman Samanta (8174058)

“…(B) Immunoblot revealed that ATG5 protein was depleted by siATG5, resulting in decreased autophagy as demonstrated by a loss of LC3-II. …”

ERP Neurocognitive tasks. by Amir H. Meghdadi (6205970)

Relative localization of TAPP2, utrophin and F-actin upon chemokine stimulation. A. by Hongzhao Li (172496)

“…</b> Relative localization of TAPP2 versus F-actin was visualized and quantified using similar methods as in A (5 experiments). A significant reduction in the overall colocalization of TAPP2 and F-actin was seen in SDF-1 stimulated cells (Student <i>t</i> test: ***p<0.001). …”

Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention by Nidia D. Pucci (5631659)

“…It increases urinary excretion of magnesium and potassium caused a significant decrease in urinary oxalate and uric acid in patients with hyperoxaluria and hyperuricosuria. …”

Hardness preference in <i>Drosophila</i> larvae, as a relevant cue for varying feeding substrates. by Nikita Komarov (11903342)

“…A”: Mechanical analyses of substrate properties of decomposing fruit (left) and hardness relative to the first measurement on day 1 identifying a decrease in hardness of dissected fruit over time, except for apple until day 5 after sectioning. …”

The Cincinnati water maze mirror version latency [s (mean ± SEM)] and number of errors (mean ± SEM) of proton irradiated and control rats. by Michael T. Williams (357796)

“…<p><b>A.</b> The overall effect on latency where irradiated groups with the exception of the 5-FLASH group took longer to locate the platform compared with controls. …”

Higher expression and nonsense mutations of Fhod3 in the DBA/2J mice and generation of Fhod3 transgenic mouse. by Ely Cheikh Boussaty (17471493)

<i>Lhfp</i> is a negative regulator of osteoblast differentiation and cortical bone mass. by Larry D. Mesner (553519)

“…<p>A) <i>Lhfp</i> transcript levels are decreased due to the five nonsense mutations created using CRISPR/Cas9 (<i>Lhfp</i>^<i>+/+</i>, N = 10; <i>Lhfp</i>^<i>+/-</i>, N = 11; <i>Lhfp</i>^<i>-/-</i>, N = 7; represents at least one mouse from each of the five mutant lines, see <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008123#pgen.1008123.t001" target="_blank">Table 1</a></b>). …”

Reduction of plasma membrane PtdIns(4)<i>P</i> and PtdIns(4,5)<i>P</i>₂ levels and their effect on the Ins<i>P</i>₃ and Ca²⁺ signals upon hormonal... by Gergő Gulyás (733813)

“…<p>(A) Schematic representation of the plasma membrane PtdIns(4,5)<i>P</i>_<b>2</b> depletion system [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125601#pone.0125601.ref033" target="_blank">33</a>]. …”

Supplementary Material for: Decline in Asthma Prevalence and Severity in Israel over a 10-Year Period by Cohen S. (3684103)

Prevalence of hypothermia on admission to recovery room remains high despite a large use of forced-air warming devices: Findings of a non-randomized observational multicenter and p... by Pascal Alfonsi (8173935)

“…Identified risk factors for Tc<36°C included age≥70 years (OR = 1.41 [CI95%: 1.02–1.94]), duration of anesthesia from 1 to 2 hours (OR = 1.94 [CI95%: 1.04–3.64]) and a decrease in Tc of >0.5°C between anesthesia induction and surgical incision (OR = 1.82 [CI95%: 1.15–2.89]). …”

Table_1_Parents‘ and healthcare professionals’ perception toward the introduction of a new fully liquid hexavalent vaccine in the Malaysian national immunization program: a cross-s... by Lama Al Bashir (11911776)

“…Moreover, a significant association (P-value ≤ 0.05) was found between physicians' age and the perception of the hexavalent vaccine's ability to decrease patient overcrowding in primary healthcare centers. …”

Severity of anaemia status among pregnant women. by Donatus Nbonibe Abaane (15909683)

“…At 28 weeks, AIP prevalence was 53.1% (95%CI:45.8, 60.3) and 37.5 (95%CI:30.6, 44.8) using a cut-off of 11.0g/dl and 10.5g/dl for those in the 2^nd trimester, respectively. …”

Corrosion behavior of API X100 steel material in a hydrogen sulfide environment by Okonkwo, Paul C.

“…The results indicate that the corrosion rate of API X100 steel decreases with increasing H2S bubbling time due to the increase in H2S concentration in 3.5% NaCl solutions. …”
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Critical proportion of ITL as a function of the insecticidal (<i>k</i>), and diversionnary effect (). by Ana O. Franco (602214)

“…Black line: , no repellency or attractancy (is the same as the white line in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0101699#pone-0101699-g004" target="_blank">Figure 4</a>); Red lines: , repellency increasing from 0.1 to 0.5 (top), at intervals of 0.1; Green lines: , attractancy increasing from −0.1 to −0.5 (bottom), at intervals of 0.1. …”