Influence of Ocean Acidification on a Natural Winter-to-Summer Plankton Succession: First Insights from a Long-Term Mesocosm Study Draw Attention to Periods of Low Nutrient Concent... by Lennart T. Bach (520701)

“…<div><p>Every year, the oceans absorb about 30% of anthropogenic carbon dioxide (CO₂) leading to a re-equilibration of the marine carbonate system and decreasing seawater pH. …”

Example of host protein coding transcripts significantly upregulated or downregulated in infected samples compared to mock infection. by Seth B. Garren (799962)

Real time PCR in SSc-MVECs of <i>MACF</i>, <i>DIAPH1</i>, <i>DIAPH</i>2, <i>ARPC3</i>, <i>RAC2</i>, <i>CDH5</i>, and <i>ITGB8</i>. by Betti Giusti (74939)

Effects of the Pgp inhibitor tariquidar (TQ; 0.5 µM) in three functional assays, in which alterations in Pgp efflux are indirectly measured by determining intracellular concentrati... by Andreas Noack (519906)

A reconnaissance provenance study of Triassic–Jurassic clastic rocks of the Russian Barents Sea by Andrey K. Khudoley (7352681)

“…The number of Palaeoproterozoic and Archean grains is very small and becomes significant only in a few Jurassic samples. ε_Nd(t) values gradually decrease from −1.5 to +2.5 in Lower Triassic rocks, to −2.0 to −8.2 in Jurassic rocks, suggesting an increasing influence of ancient metamorphic basement erosion in the younger Jurassic rocks. …”

Patterns of avian haemosporidian infections vary with time, but not habitat, in a fragmented Neotropical landscape by Juan Rivero de Aguilar (5917271)

“…We also found a temporal effect, with birds at the end of the five-month study (which ran from the end of the rainy season thru the dry season), being less infected by <i>Plasmodium</i> parasites than individuals sampled at the beginning. …”

Mutagenesis of the CXCL10 binding site on <i>L</i>. <i>(L</i>.<i>) major</i> GP63 to <i>L</i>. <i>(V</i>.<i>) panamensis</i> residues reduces CXCL10 cleavage and T cell chemotaxis. by Alejandro L. Antonia (7147739)

“…(L.) major gp63 <i>allele (D463) to the</i> L. (V.) panamensis <i>allele (N463) at the CXCL10 binding site decreases CXCR3</i>^<i>+</i> <i>T cell chemotaxis</i>. …”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Dexmedetomidine Acts via the JAK2/STAT3 Pathway to Attenuate Isoflurane-Induced Neurocognitive Deficits in Senile Mice by Yanna Si (3234477)

“…Cognitive function was assessed 19 days later using a 5-day testing regimen with Morris water maze. …”

A 10-Year Trend Analysis of Heart Failure in the Less Developed Brazil by Amanda D. F. Fernandes (8618637)

“…Pearson correlation and linear-by-linear association test for trends were calculated, with a level of significance of 5%. Results: From 2008 to 2017, HF admissions decreased 62% (p = 0.004) in Paraiba and 34% (p = 0.004) in Brazil. …”

Quality of life in individuals with spinocerebellar ataxia type 10: a preliminary study by Laudiane Reis Santos (5762018)

“…The longer the disease duration (p = 0.02), risk of falling (p = 0.04), severity of ataxia (p = 0.00) and functional dependence in activities of daily living (p = 0.03) and instrumental activities of daily living (p = 0.00), the worse the QoL was in the “physical functioning” domain, with a decrease of 1.62 points for each year of disease duration. …”

Supplementary Material for: Stair-Case/Honeycomb Maculopathy in Alport Syndrome: A Case Report by figshare admin karger (2628495)

“…Introduction: Alport syndrome is an inherited disease caused by mutations in COL4A5, COLA3, or COL4A4 resulting in kidney failure, hearing loss and ocular symptoms. …”

There is a non-linear relationship between <i>FOXO</i> expression and nutritional plasticity. by Hui Yuan Tang (196925)

“…Circles indicate flies in which we have manipulated <i>FOXO</i> expression using UAS-GAL4, diamonds indicate wild-type flies reared at different temperatures (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002373#pgen.1002373.s005" target="_blank">Figure S5</a>). …”

Transcriptional regulation of <i>AaERR</i> by EcR/USP bound to 20E. by Dan-Qian Geng (18137370)

Schematic of Unstable Multiple-Peak Solution in a Mass Conserved Reaction–Diffusion System by Mikiya Otsuji (75660)

“…The u-form molecules convert v-form molecules into u-form, and this positive feedback is so strong under the condition where ∂<i>P_e</i>/∂<i> N̄</i> < 0 [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030108#pcbi-0030108-b048" target="_blank">48</a>] that infusion of molecules into the space causes a decrease in v-form molecules. …”

A partial genome assembly of the miniature parasitoid wasp, <i>Megaphragma amalphitanum</i> by Fedor S. Sharko (6575339)

Tongue coupling as a therapeutic strategy: electromyographic analysis of different training approaches by Loslene Goulart Souza (12826660)