Glycolytic inhibitor 2-DG alters downstream AMPK and mTOR signaling, and neuronal gene expression, but does not affect Wnt signaling. by Roaya S. Alqurashi (11243136)

“…Representative western blots with quantified data showed 2-DG treatment at day 5 post-SE with pilocarpine inhibit mTOR signaling downstream activation by decreased pP70S6K^T389 and activating pAMPKα^T172. …”

Increasing Notch1 activity in MAFs suppresses tumor angiogenesis. by Hongwei Shao (493627)

“…<i>Top</i>: representative images; <i>Bottom</i>: relative blood vessel density calculated as % of red pixel in total area examined by confocal microscopy. Data are mean ± SD, n = 5 tumors/group. <b>B.</b> Significantly decreased blood vessel density is observed in 1205Lu co-grafted with N1^IC-GFP/MAF. …”

Agonist-driven FRET changes parallel binding and cellular efficacies of agonists. by Seungwoo Chang (306656)

“…<p>A. Cch binding (filled circle) and Cch-driven FRET changes (open circle) were measured using membranes prepared from FlAsH-labeled HeLa cells that expressed M1S2. …”

Lentiviral vector transduction increases Rituximab tolerance in GCB-Like cell lines. by Benyamin Ranjbar (2591266)

“…<b>(d)</b> Lentivirus-mediated increase of tolerance to Rituximab in GCB-Like DLBCL cell lines (OCI-Ly-7, SU-DHL-5), but not in ABC-Like cells. <b>(e)</b> Decrease of cell proliferation in OCI-Ly-7 and SU-DHL-5 cells treated with lentiviral vectors. …”

Datasets for Reduction of Equatorial Obduction by Atmospheric Intraseasonal Oscillations in the Western and Central Pacific Ocean by Ling Ling Liu (12337583)

“…The results suggest that the ISOs can reduce the annual obduction rate of the western and central equatorial Pacific Ocean (WCEPO; 150°E-160°W, 5°S-5°N) by ~12%, and their impact on the eastern Pacific is rather limited. …”

Data_Sheet_1_Unicellular Eukaryotic Community Response to Temperature and Salinity Variation in Mesocosm Experiments.PDF by Natassa Stefanidou (5830481)

“…We used mesocosm experiments and Next Generation Sequencing to study the response of the natural Baltic and Mediterranean unicellular eukaryotic plankton communities (control and +6°C heat shock) to subsequent salinity changes (-5 psu, +5 psu). The impact on Operational Taxonomic Unit (OTU) richness, taxonomic and functional composition and rRNA:rDNA ratios were examined. …”

Physical training reverses changes in hepatic mitochondrial diameter of Alloxan-induced diabetic rats by Gabriel Keine Kuga (5611532)

“…The exercise protocol consisted of swimming with a load of 2.5% of body weight for 60 minutes per day (5 days per week) for the trained control and Trained Diabetic Groups, during 6 weeks. …”

Decitabine increased CD34 expression and reduced cell proliferation in transduced human CD34⁺ cells. by Naoya Uchida (267792)

“…<p>(a). To further investigate the decitabine effects on transduction efficiency for human CD34⁺ cells, we added increasing dose of decitabine (0.05, 0.1, 0.2, and 0.5 µM) into media during 24-hour prestimulation (SCF, FLT3L, TPO, and IL3). …”

The protein L-isoaspartyl <i>O</i>-methyltransferase (PCM-1) opposes insulin-like signaling to extend <i>C. elegans</i> lifespan. by Shilpi Khare (187717)

“…<p>Upon binding of the insulin-like ligand to the DAF-2 receptor, the AGE-1 kinase is activated and phosphorylates membrane-bound phosphatidylinositol-4,5-bisphosphate (PIP₂ ), leading to the formation of phosphatidylinositiol-3,4,5-trisphosphate (PIP₃) and recruitment of kinases PDK-1 and AKT-1/AKT-2/SGK-1 complex to the membrane. …”

Effects of CpG-ODN C treatment in <i>Trypanosoma evansi</i> infected and uninfected rabbits. by Parveen Kumar (428921)

“…<p>The rabbits of group I were infected with 1x10⁵<i>T</i>. <i>evansi</i> parasites/animal. …”

Suppressive effect of arginine and sodium fluoride on enamel calcium loss and antibiofilm activity on mature oral microcosm biofilms by Daniela Alejandra Cusicanqui Méndez (5560673)

“…While all treatments resulted in a reduction of α-EPS, 8% arginine showed the most pronounced effect, being the only treatment to decrease β-EPS compared to the control. …”

Climate change has likely already affected global food production by Deepak K. Ray (423970)

“…However, current impacts on a diversity of crops subnationally and implications for food security remains unclear. …”

Hypoxia restricts larval growth and induces lipid metabolic changes distinct from starvation. by Daniel M. Wong (679523)

“…White arrows point to the larval fat body. [<b>E–G′</b>] Control larvae reared under hypoxic (<i>promE(800)>2xEGFP</i>) and starvation (<i>w¹¹¹⁸</i>) conditions exhibited increased lipid droplet accumulation in the larval fat body (<b>F, G</b>), compared to the control (<b>E</b>). …”

Decomposition of the effects of long-lasting recording with 1 mM ATP-patch clamp-pipettes. by Marta Martini (429411)

“…</b> Same protocols as in <b>A</b>, applied in the same cell 8 min later. Note the drastic decrease in IKD amplitude and the monotonic increase in the I–V curves (as opposed to panel <b>A</b>). …”

The escape response stimulates FLP-18 release from the AVA and RIM. by Jeremy T. Florman (12192010)

“…The spikes in velocity coincide with the initiation of the escape response (D-E) Quantification of fluorescence (arbitrary units–a.u.) in the AVA (D), RIM (E), and coelomocytes (F), at 0-, 1- and 2-hour time points. …”

Clinical Efficacy Results. by Satish Keshav (65388)

“…<p>The percentage of subjects who had a CDAI decrease of at least 70 points is shown at each Induction period study visit after the baseline (A). …”

Evidence of local mechanical control for bone formation and resorption. by Friederike A. Schulte (406501)

“…(D) Mechanical regulation in the CTR group. (E) Sagittal sections through CV6 at (bottom) 0 and (top) 12 weeks after ovariectomy (OVX) (F) OVX causes a strong decrease in BV/TV compared to SHAM-operation (SHM). …”

Table_1_Muscle Loss During Androgen Deprivation Therapy Is Associated With Higher Risk of Non-Cancer Mortality in High-Risk Prostate Cancer.docx by Pai-Kai Chiang (11448058)

“…Body mass index changes were highly and weakly correlated with changes in TATI and SMI, respectively (Spearman ρ for TATI, 0.78, p<0.001; ρ for SMI, 0.27, p=0.003). As a continuous variable, each 1% decrease in SMI was independently associated with a 9% increase in the risk of non-cancer mortality (hazard ratio: 1.09; p=0.007). …”

Termites' effects on arboreal predators. by Robert M. Pringle (248396)

“…Experimental prey supplementation at 30 m essentially equalized mean occupation rates at 10 m and 30 m (red markers; time × proximity interaction: <i>F</i>_1,33 = 7.5, <i>p</i><0.01; <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000377#pbio.1000377.s008" target="_blank">Table S3</a>). …”

PREDICTIVE MAINTENANCE PRACTICES & STANDARDS by Jeremy Wayne Byrd (6661946)