SERBP1 is a component of the Liver Receptor Homolog-1 transcriptional complex by Yelenis Mari (725499)

“…In contrast, receptor overexpression decreased only SERBP1 mRNA levels. Consistent with these data, in a promoter:reporter assay, binding of NR5A2 to the promoter region of SERBP1 resulted in a decrease in the expression level of the reporter gene, and subsequently, inhibiting transcription. …”

SERBP1 is a component of the Liver Receptor Homolog-1 transcriptional complex by Yelenis Mari (725499)

“…In contrast, receptor overexpression decreased only SERBP1 mRNA levels. Consistent with these data, in a promoter:reporter assay, binding of NR5A2 to the promoter region of SERBP1 resulted in a decrease in the expression level of the reporter gene, and subsequently, inhibiting transcription. …”

A Humanized Mouse Model of HPV-Associated Pathology Driven by E7 Expression by Águeda Buitrago-Pérez (149456)

“…Finally, our findings indicate a decrease of the <em>in vitro</em> capacity of HPV5 E7 to reduce pRb levels <em>in vivo</em>, possibly explaining the phenotypical differences when compared with 16E7-grafts. …”

The power-law exponent for both the (a) positive and (b) negative tail. by Lu Liu (171341)

“…<p> decreases from Bach to Mendelsohn/Chopin [Note the horizontal coordinates corresponding to the five symbols in either (a) or (b) denote the birth years of the five composers from Bach to Chopin, respectively]. …”

Curcumin inhibits growth and reduces viability in a MscL-dependent manner. by Robin Wray (359090)

“…B) Reduction in viability after curcumin treatment shown as percent decrease in CFU’s relative to untreated. n = 3–5 and. error bars show standard error of the mean (SEM).…”

Reversal rates as a function of dot luminance of the two motion-defined surfaces. by P. Christiaan Klink (180011)

“…Logically following from the demonstrated effect of dot-luminance induced percept probability on the mean dominance durations (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003473#pone-0003473-g003" target="_blank">fig. 3</a> & <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003473#pone-0003473-g004" target="_blank">fig. 4</a>) these plots demonstrate that for both the group data and the individual observers' reversal rates decrease when the luminance difference between the two surfaces increases. …”

Selective recognition of human small transthyretin aggregates by a novel monoclonal antibody by A. C. Teixeira (13849252)

“…CE11 only recognises the highly amyloidogenic TTR variants L55P, S52P, A97S, Y78F or acidified TTR wt preparations. At the same time, this clone was negative for TTR V30M, soluble wild type protein or TTR T119M. …”

Effect of targeted genetic inactivation of the <i>PRR</i> in the UB on <i>Aqp2, Foxi1, AE1</i> and H⁺-ATPase subunit <i>α4</i> mRNA expression in the mouse metanephros o... by Renfang Song (582909)

“…<p>A–H: Representative images of E18.5 section <i>in situ</i> hybridization. …”

The expression of pain receptors in <i>α</i>-GalA KO males frontal paws. by Jarmila Lakomá (152379)

“…B) The western blot analysis of Nav1.8 expression (∼220 kDa) in the whole protein extract from skin of frontal paws confirmed 1.5 fold increased protein expression of Nav1.8 in case of α-GalA KO males (n = 5) when compared to WT males (n = 5), p = 0.0246. …”

Selection of shorter cell-free DNA fragments enriched for ctDNA. by Hunter R. Underhill (3151677)

Nanoporous Silica Preconcentrator for Vapor-Phase DMNB, a Detection Taggant for Explosives by Coco Day (9121340)

“…The loading time and loading temperature of pSiO₂ were varied systematically between 15 and 60 min and 5–20 °C, respectively. The preconcentrator’s performance was compared to that of a nonporous substrate of the same material as a control. …”

Data_Sheet_3_Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subun... by Qiuju Wang (7400)

“…The addition of psilocybin upregulated the expression levels of PIK3CB and AKT. A significant decrease (p < 0.05) in PIK3CB and mTOR protein expression levels was detected after the addition of LY294002 and rapamycin. …”

Data_Sheet_1_Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subun... by Qiuju Wang (7400)

“…The addition of psilocybin upregulated the expression levels of PIK3CB and AKT. A significant decrease (p < 0.05) in PIK3CB and mTOR protein expression levels was detected after the addition of LY294002 and rapamycin. …”

Data_Sheet_2_Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subun... by Qiuju Wang (7400)

“…The addition of psilocybin upregulated the expression levels of PIK3CB and AKT. A significant decrease (p < 0.05) in PIK3CB and mTOR protein expression levels was detected after the addition of LY294002 and rapamycin. …”

Risk and effort have differing effects on the distribution of a project’s value. by Kevin Gross (637614)

“…<p>Each panel shows the cumulative distribution function <i>F</i>(<i>v</i>;<i>r</i>,<i>e</i>) of a project’s value <i>v</i>. …”

Fibrous osteodystrophy due to secondary renal hyperparathyroidism in a senile dog by Y.A. Rossi (14343753)

“…Oral x-rays showed loss of dental bone support and decreased bone radiopacity. Chest radiographs showed decreased density in the ribs and costochondral junction; on the other hand, organs of the cardiorespiratory system showed no changes. …”

Cux1 binds a similar, but not identical, motif to that identified for Miz-1. by Bonnie L. Barrilleaux (591338)

“…Relative binding intensity of Miz-1 and Cux1 to P1 versus P2 in (C) is defined as the intensity of bound probe in lane 2/lane 5 for Miz-1, and lane 3/lane 6 for Cux1. (D) Cux1-overexpressing HeLa cells show a decrease in luciferase activity when the core Cux1 binding motif (ATCGAT) is present in the reporter vector, but not when the reporter vector contains Mizm1, which does not contain ATCGAT. * <i>p</i><0.05; ** <i>p</i><0.01; *** <i>p</i><0.001.…”

Robotically-Assisted Mitral Valve Commissuroplasty: An Easy Fix for a Complex Jet by Igo Ribeiro (8947467)

“…Then run this suture from the reference point to the annulus and back to the reference point where it is tied up.…”

NUMERICAL SIMULATION OF COAL GASIFICATION IN A CIRCULATING FLUIDIZED BED GASIFIER by Vikrant Sharma (4348579)

Ligand Aspect Ratio as a Decisive Factor for the Self-Assembly of Coordination Cages by Suzanne M. Jansze (1403719)