FAK, but not Pyk2 is required for GPVI-mediated ROS generation and platelet aggregation. A. by Naadiya Carrim (664456)

“…<p>Washed human platelets (2.5×10⁸/mL) preloaded with 10 µM H₂DCFDA (for ROS experiments only) were pre-treated with vehicle control (0.1% DMSO), FAK inhibitor (1 µM PF-228), Pyk2 inhibitor (10 µM Tyrphostin A9) or Syk inhibitor (5 µM BAY), then stimulated with 1 µg/mL CRP and monitored for ROS generation (i) and platelet aggregation (ii). …”

PLB is a target gene of miRNA 221. by Hongyu Li (1332669)

All Ca_V3.3 variants left-shift the voltage dependence of inactivation. by Yousra El Ghaleb (22075892)

Subjects:

<i>T</i>_m values of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

Catalytic fold of WT PARG1 C1-GAP domain for RhoA interaction. by Zen Kouchi (14898435)

Fig 5 - by Pierre Bauvin (18154818)

Hypoxia induced decreases in dendritic spine density, length, soma size and volume of the apical and basal branches of CA1 and CA3 pyramidal neurons. by Chun-Sing Lam (695733)

Mutation of four arginine residues in P34 leads to a decrease in binding between P34 and L5. by Anyango D. Kamina (4034165)

Environmental Enrichment on <i>Mecp2^−/y</i>-EE mice induces a decrease in the expression of a set of synaptic plasticity-related genes. by Bredford Kerr (363408)

Fig 5 - by Melissa A. Hill (13170105)

LD- and haplotype-based measures of epistasis identify a narrow time window of epistasis detectability. by Gabriele Pedruzzi (5753792)

Detection of epistasis is confined in a time window whose width is controlled by the mean selection coefficient. by Gabriele Pedruzzi (5753792)

NBCe1 and NBCe2 protein and mRNA expression in hRPTCs carrying wild-type (WT) or homozygous variant (HV) <i>SLC4A5</i>. by John J. Gildea (845025)

“…<b>D) <i>SLC4A4</i> mRNA.</b> <i>SLC4A4</i> mRNA is decreased following an increase in intracellular sodium (monensin, 1 μmol/L, 24 h) (↑Na⁺) only in WT <i>SLC4A5</i> hRPTCs (N = 9, *P<0.05 vs. …”

Levels of resistance of alphavirus RNA translation to IFN-β is determined by 5’UTRs of their genomes. by Josephine M. Reynaud (732822)

Overview of study procedures. by Matthew G. Vinson (22593374)

“…VIDEO and CONTROL were associated with a similar rise in intent to decrease OTC NSAID use (1.92 (SD: 4.41) vs. 1.36 (SD: 3.46), p = 0.150) and a similar decrease in NSAIDs exposure (−32.8% in VIDEO and −36.5% in CONTROL, p = 0.520) 4 weeks post-intervention. …”

Genes involved in lipid metabolism that are differentially expressed in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

Genes involved in carbohydrate metabolism differentially expressed in liver of <i>Fmo5</i>^<i>-/-</i> mice compared with WT mice. by Ian R. Phillips (5074121)

Kolmogorov-Smirnov (KS) test for the different parameter value pairs at a 95% confidence level. We tested the null hypothesis for all parameters: The RMSEs obtained for one pair of... by Cyrine Chenaoui (22177098)

Overlapping end points of ice sublimation and desorption drying as detected by temperature probes and Pirani gauge pressure measurements by Geoff Smith (6064268)

“…</p><p dir="ltr">In both cases of temperature measured or predicted in the vial, and the vapour detected in the drying chamber, the trajectories of the end point defining characteristics for sublimation and desorption are in the same direction; either showing a positive gradient that gets less steep (in the case of TC probes) or a negative gradient which gets less steep (in the case of the Pirani curve).…”

Assessing the usage of end-of-life tire pyrolysis oil as an alternative fuel in a diesel engine in the point of energy, exergy, exergoeconomic, exergoenviroeconomic, and sustainabi... by Talha Ertürk (19715855)

“…Under the same conditions, it was calculated as 5,958.2 kg CO₂/month for D100. In the context of an SI based on load, a reduction of 5.89% was observed in the case of conventional D100 in comparison with TP40 in the CI engine operating at full load. …”