Representative Staining of Peripheral Blood during immunosuppression by cyclophosphamide. by Andrew S. Wagner (11331477)

Representative scatter plots of leukocyte populations during 1A8 neutrophil depletion. by Andrew S. Wagner (11331477)

S6 Fig - by Penny A. Rudd (10298691)

S1 Table - by Penny A. Rudd (10298691)

S2 Table - by Penny A. Rudd (10298691)

Experimental design and model validation. by David J. Braun (7107692)

“…Animals from both WT and AD p38^KO groups had significant decreases in p38α transcript levels (>8 log₂ fold change [FC]) compared to their respective p38^+/+ control groups (1-way ANOVA; <i>F</i>_(3,12) = 297.4, <i>p</i> ≤ 0.0001), indicating that the genetic manipulation was successful. …”

SNARE proteins rescue impaired autophagic flux in Down syndrome by Stefanos Aivazidis (3944795)

“…Based on our previous observations of PN disruption in DS, we investigated possible dysfunction of the autophagic machinery in human DS fibroblasts and other DS cell models. Following induction of autophagy by serum starvation, DS fibroblasts displayed impaired autophagic flux indicated by autophagolysosome accumulation and elevated p62, NBR1, and LC3-II abundance, compared to age- and sex-matched, euploid (CTL) fibroblasts. …”

Virtual-Partition Digital PCR for High-Precision Chromosomal Counting Applications by Lucien Jacky (10197624)

“…This demonstration assaytested on 432 samples contrived from sheared cell-line DNA at multiple input concentrations and simulated fractions of euploid or trisomy-21 “fetal” DNAis analyzed using both traditional dPCR thresholding and VPdPCR. …”

Genome instability in STRIPAK complex mutants. by Patricia P. Peterson (20291306)

“…<p>(A) Read depth analyses from whole-genome sequencing of the WT/WT (CnLC6683) parental diploid strain and heterozygous mutant diploid strains. The WT/WT genome is euploid, while <i>PPH22/pph22</i>Δ and <i>MOB3/mob3</i>Δ strains exhibit multiple instances of segmental and whole chromosome aneuploidy, with dark blue and orange highlighting regions/chromosomes with increased and decreased read depth, respectively. …”

DataSheet1_Blocking S100A9-signaling is detrimental to the initiation of anti-tumor immunity.pdf by Melike Fusun Demir (19919784)

“…This effect was caused by a reduction in the tumor immune infiltration to about half of untreated controls, and the reduction was made up of a 5-fold decrease in Ly6C^high monocytic cells. …”

Image_1_Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.tif by Jehan Alam (5577734)

“…Comparison of gene expression between the MHCII^- monocyte and MHCII⁺ populations in non-stressed conjunctiva revealed a ≥ 2 log² fold increase in 95 genes and decrease in 46 genes. …”

Image_2_Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.tif by Jehan Alam (5577734)

“…Comparison of gene expression between the MHCII^- monocyte and MHCII⁺ populations in non-stressed conjunctiva revealed a ≥ 2 log² fold increase in 95 genes and decrease in 46 genes. …”

Image_1_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.tif by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Table_1_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.xlsx by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Table_4_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.xlsx by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Table_2_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.xlsx by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Table_7_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.xlsx by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Table_6_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.xlsx by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Table_5_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.xlsx by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”

Image_2_Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis.tif by Helle Bach Søndergaard (10044584)

“…Of these, 12 miRNAs were downregulated in pregnancy and 6 of the 15 miRNAs were altered by more than ±2-fold (+2.99- to -6.38-fold). Pregnant MS patients had a highly significant increase in the percentage of monocytes and a decrease of NK-cells and myeloid dendritic cells compared to non-pregnant MS patients. …”