Image 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Table 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.xlsx by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Expression analysis of downstream target genes in the p38/MAPK signaling pathway across myeloid leukemia cell lines. by Ajeet P. Singh (22298432)

Subjects:

Adaptive phenotypic modulations lead to therapy resistance in chronic myeloid leukemia cells by Seda Baykal-Köse (8501583)

“…CD34 negativity, high expression of E-cadherin and CD44; decreased levels of CD45 and β-catenin do not fully confer with the leukemic stem cell (LSC) phenotype. …”

Rosa26 locus–based Zeb2 hematopoietic-restricted overexpression leads to extramedullary hematopoiesis/splenomegaly, enhanced myeloid cell development, and monocyte lineage skewing.... by Jueqiong Wang (11467505)

Table_1_Mass cytometry reveals the corneal immune cell changes at single cell level in diabetic mice.docx by Limin Qin (10875474)

“…Comprehensive immunological profiling indicated remarkable changes in the immune microenvironment in diabetic corneas, characterized by a notable decrease in CD103+CD8+ tissue-resident memory T (T_RM) cells and Tregs, as well as a dramatic increase of γδT cells and subsets of CD11b+Ly6G+ myeloid-derived suppressor cells (MDSCs).…”

Table_2_Mass cytometry reveals the corneal immune cell changes at single cell level in diabetic mice.docx by Limin Qin (10875474)

“…Comprehensive immunological profiling indicated remarkable changes in the immune microenvironment in diabetic corneas, characterized by a notable decrease in CD103+CD8+ tissue-resident memory T (T_RM) cells and Tregs, as well as a dramatic increase of γδT cells and subsets of CD11b+Ly6G+ myeloid-derived suppressor cells (MDSCs).…”

Hematopoietic-specific loss of Zeb1 leads to differentiation defects in myeloid lineages and specific HSPC populations. by Jueqiong Wang (11467505)

“…<b>(C)</b> Flow cytometric analysis of PB of reconstituted mice showed defects in <i>Zeb1</i> null HSPC contribution to myeloid cells (Cd11b⁺) including monocytic (Cd11b⁺Ly6G⁻) and NEU (Cd11b⁺Ly6G⁺) lineage cells. …”

Table_2_Distinct Patterns of Myeloid Cell Infiltration in Patients With hrHPV-Positive and hrHPV-Negative Penile Squamous Cell Carcinoma: The Importance of Assessing Myeloid Cell D... by Tynisha S. Rafael (10965960)

“…Regarding the association between myeloid cell densities and disease-specific survival, the risk of death was found to decrease slightly as the number of myeloid cells in the IT tumor compartment increased (CD14+ p = 0.04; CD68+ p = 0.05; CD163+ p = 0.02). …”

Table_1_Distinct Patterns of Myeloid Cell Infiltration in Patients With hrHPV-Positive and hrHPV-Negative Penile Squamous Cell Carcinoma: The Importance of Assessing Myeloid Cell D... by Tynisha S. Rafael (10965960)

“…Regarding the association between myeloid cell densities and disease-specific survival, the risk of death was found to decrease slightly as the number of myeloid cells in the IT tumor compartment increased (CD14+ p = 0.04; CD68+ p = 0.05; CD163+ p = 0.02). …”

Representative images of red blood cells after PCP addition. by Aleeza Namit (12295157)

Subjects:

Inhibition of VCP leads to accumulation of ubiquitylated proteins and activates the unfolded protein response (UPR) in human acute myeloid leukemia (AML) cells. by Paweł P. Szczęśniak (12359841)

Subjects:

Immunosenescence: participation of T lymphocytes and myeloid-derived suppressor cells in aging-related immune response changes by Amanda Soares Alves (6676898)

“…As already reported, some changes in this system are observed, including reduced number and repertoire of T cells due to thymic involution, accumulation of memory T cells by chronic infections, homeostatic proliferation compensating for the number of naïve T cells, decreased proliferation of T cells against a stimulus, telomere shortening, replicative senescence of the T cells, and inflammaging, besides the accumulation of myeloid-derived suppressor cells. …”

miR-1469 transfection of melanoma cell lines does not alter viability or proliferation. by Mallory J. DiVincenzo (11372420)

Subjects:

Impairment of <i>P</i>. <i>berghei</i> liver infection by <i>T</i>. <i>brucei</i> lysates is independent of lymphoid and myeloid immune cells. by Adriana Temporão (7841300)

K-macrophages from TcpC-secreting CFT073 induced pyelonephritis murine model show decreased levels of MyD88 proteins. by Jia-qi Fang (10508867)

Supplementary Material for: Adoptively Transferred in vitro-Generated Myeloid-Derived Suppressor Cells Improve T-Cell Function and Antigen-Specific Immunity after Traumatic Lung In... by Kustermann M. (12857240)

“…Although myeloid-derived suppressor cells (MDSCs) are initially described as T-cell suppressors, their immunomodulatory capacity after trauma is mostly undefined. …”

Increase of MLF knock down efficiency during vegetative growth using strategy 2 compared to strategy 1. by Zi-Qi Lin (6444350)