Erakusten 1 - 20 emaitzak -- 25 bilaketa honetara '(( first two bound ) OR ( first two found ))', Bilaketaren denbora: 0,10s Findu emaitzak
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    Imlunestrant: First Approval nork Susan J. Keam (6594447)

    Argitaratua 2025
    “...This article summarizes the milestones in the development of imlunestrant leading to this first approval for use in patients with ER+, HER2-, ESR1-mutated advanced or metastatic breast cancer....”
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    Comparing Force Field Treatments in QM/MM Studies of the SARS-CoV‑2 RNA-Dependent RNA Polymerase (RdRp) Mechanism nork Maite Roca (1678066)

    Argitaratua 2025
    “...This mechanism was found to be exergonic, with the rate-determining step being the nucleophilic attack, having a free energy barrier of 15.2 kcal mol<sup>–1</sup>. ...”
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    Development of FBXO22 Degraders and the Recruitment Ligand 2‑Pyridinecarboxyaldehyde (2-PCA) nork Tian Qiu (156003)

    Argitaratua 2025
    “...Finally, we found that 2-pyridinecarboxaldehyde (2-PCA) functions as a novel electrophilic degron capable of forming a reversible thioacetal with cysteine 326 for recruiting FBXO22. ...”
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    Development of FBXO22 Degraders and the Recruitment Ligand 2‑Pyridinecarboxyaldehyde (2-PCA) nork Tian Qiu (156003)

    Argitaratua 2025
    “...Finally, we found that 2-pyridinecarboxaldehyde (2-PCA) functions as a novel electrophilic degron capable of forming a reversible thioacetal with cysteine 326 for recruiting FBXO22. ...”
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    Application of STUPPIT to identify novel intermediary proteins between SMAD4 and β-catenin, central hubs of BMP and Wnt pathway. nork Lin Xie (136792)

    Argitaratua 2025
    “...Underlying mass spectrometry data can be found in the ProteomeXchange (PXD069286).</p>...”
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    Root mean square deviation measurements of monomers. nork Oluwatoyin Campbell (14392137)

    Argitaratua 2025
    “...<p><b>A)</b> RMSD of monomer 1 (p1) and <b>B)</b> monomer 2 (p2) calculated using the first frame of each protein as the reference in each case. ...”
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    Analysis of the binding site of NagS and activity of NagS mutants. nork Chao Li (145513)

    Argitaratua 2025
    “...<p><b>(a)</b> NagS active site with bound GlcNAc-6P (gray carbons), protein residues are coloured with pale blue and yellow carbons to indicate the 2 monomers forming the active site. 2|Fo|-|Fc| electron density contoured at 1.2 σ is shown as cyan mesh. ...”
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    Image 1_Dynamic duos: learning to care as a pair in the biparental prairie vole (Microtus ochrogaster).jpeg nork Taylor D. Hinton (22687397)

    Argitaratua 2025
    “...</p>Methods<p>We investigated how prairie voles learn to be parents by observing how their parental care effort changes over two consecutive litters. The first litter represents a naive context while the second litter represents an experienced context....”
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    Suggested set of research activities and tools for the RITEC (Children's Digital Play and Well-being) research project nork Fiona Scott (6434120)

    Argitaratua 2025
    “...</p><p dir="ltr"><br></p><p dir="ltr"><b>Visit 3 ‘Two weeks post-DPE’</b><br>Around two weeks after Visit 2, researchers conducted further interviews and video observations to understand ongoing use of the game. ...”
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