The Pseudo-Code of the IRBMO Algorithm. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Distributions of model parameters mirror differentially expressed ion channel genes. حسب Daniele Linaro (227790)

IRBMO vs. meta-heuristic algorithms boxplot. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

IRBMO vs. feature selection algorithm boxplot. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>" حسب Doga CEDDEN (12675286)

"…</p><p><br></p><p dir="ltr">Chapter 4 introduces the dsRIP web platform (<a href="https://dsrip.uni-goettingen.de/" target="_blank">https://dsrip.uni-goettingen.de/</a>) for designing sequence-optimized dsRNA for RNAi-based pest control. In the experimental part, small interfering RNA (siRNA) features that were associated with RNAi efficacy in human cells were tested in <i>T. castaneum </i>by targeting an essential gene and measuring insecticidal efficacy. …"

<i>hi</i>PRS algorithm process flow. حسب Michela C. Massi (14599915)

"…From this dataset we can compute the MI between each interaction and the outcome and <b>(D)</b> obtain a ranked list (<i>I</i>_<i>δ</i>) based on this metric. <b>(E)</b> Starting from the interaction at the top of <i>I</i>_<i>δ</i>, <i>hi</i>PRS constructs <i>I</i>_<i>K</i>, selecting <i>K</i> (where <i>K</i> is user-specified) terms through the greedy optimization of the ratio between MI (<i>relevance</i>) and a suitable measure of similarity for interactions (<i>redundancy)</i> (cf. …"

Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures حسب Dibyajyoti Das (14845321)

"…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …"

Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures حسب Dibyajyoti Das (14845321)

"…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …"

Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures حسب Dibyajyoti Das (14845321)

"…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …"

Pseudo Code of RBMO. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

P-value on CEC-2017(Dim = 30). حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Memory storage behavior. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Elite search behavior. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Description of the datasets. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

S and V shaped transfer functions. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

S- and V-Type transfer function diagrams. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Collaborative hunting behavior. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

Friedman average rank sum test results. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

IRBMO vs. variant comparison adaptation data. حسب Chenyi Zhu (9383370)

"…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …"

DataSheet_1_Machine Learning Uses Chemo-Transcriptomic Profiles to Stratify Antimalarial Compounds With Similar Mode of Action.pdf حسب Ashleigh van Heerden (11041338)

"…We developed a rational gene selection approach that could identify predictive features for MoA to train and generate ML models. …"