Table 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf حسب Valentina Di Salvatore (6296114)

"…Parallelly, we trained a Random Forest regression model on simulated lipid nanoparticles formulations to predict immune activation values and embedded this model into a genetic algorithm to identify optimal lipid nanoparticles design parameters (size, charge, polyethylene glycol content, and targeting). …"

Presentation 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf حسب Valentina Di Salvatore (6296114)

"…Parallelly, we trained a Random Forest regression model on simulated lipid nanoparticles formulations to predict immune activation values and embedded this model into a genetic algorithm to identify optimal lipid nanoparticles design parameters (size, charge, polyethylene glycol content, and targeting). …"

Table 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf حسب Valentina Di Salvatore (6296114)

"…Parallelly, we trained a Random Forest regression model on simulated lipid nanoparticles formulations to predict immune activation values and embedded this model into a genetic algorithm to identify optimal lipid nanoparticles design parameters (size, charge, polyethylene glycol content, and targeting). …"

Image 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png حسب Valentina Di Salvatore (6296114)

"…Parallelly, we trained a Random Forest regression model on simulated lipid nanoparticles formulations to predict immune activation values and embedded this model into a genetic algorithm to identify optimal lipid nanoparticles design parameters (size, charge, polyethylene glycol content, and targeting). …"

Image 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png حسب Valentina Di Salvatore (6296114)

"…Parallelly, we trained a Random Forest regression model on simulated lipid nanoparticles formulations to predict immune activation values and embedded this model into a genetic algorithm to identify optimal lipid nanoparticles design parameters (size, charge, polyethylene glycol content, and targeting). …"

MultiCRISPR-EGA: Optimizing Guide RNA Array Design for Multiplexed CRISPR Using the Elitist Genetic Algorithm حسب Yangyu Zhang (4609117)

"…Computational experiments on Escherichia coli gene targets demonstrate that the EGA can rapidly optimize multiplexed gRNA arrays, outperforming other intelligent optimization algorithms in CRISPR interference (CRISPRi) applications, while the GUI provides real-time design progress control and compatibility with various CRISPR-Cas systems. …"

Study design flow chart. حسب Müge Yalçin (16486563)

Table1_A depth-first search algorithm for oligonucleotide design in gene assembly.DOCX حسب Hanjie Liang (12253847)

"…Then, the improved depth-first search algorithm is used according to the design principle of pruning optimization to obtain a uniform set of oligonucleotides with very close melting temperatures. …"

<i>OptRAM</i>: <i>In-silico</i> strain design via integrative regulatory-metabolic network modeling حسب Fangzhou Shen (5140994)

"…In this study, we developed a novel strain design algorithm, named OptRAM (<b>Opt</b>imization of <b>R</b>egulatory <b>A</b>nd <b>M</b>etabolic Networks), which can identify combinatorial optimization strategies including overexpression, knockdown or knockout of both metabolic genes and transcription factors. …"

Optimal ALARM BN discovered by CausNet. حسب Nand Sharma (21519845)

الموضوعات:

Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures حسب Dibyajyoti Das (14845321)

الموضوعات:

Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures حسب Dibyajyoti Das (14845321)

الموضوعات:

Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures حسب Dibyajyoti Das (14845321)

الموضوعات:

Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>" حسب Doga CEDDEN (12675286)

"…</p><p><br></p><p dir="ltr">Chapter 4 introduces the dsRIP web platform (<a href="https://dsrip.uni-goettingen.de/" target="_blank">https://dsrip.uni-goettingen.de/</a>) for designing sequence-optimized dsRNA for RNAi-based pest control. …"

Indels characterization algorithm development and benchmark with simulated data and real data. حسب Marta Sanvicente-García (12306659)

UpSet diagram illustrating the overlap of DNBs selected by our method and top-ranked genes by the 13 baseline centrality-based ranking algorithms. حسب Fatemeh Keikha (20917848)

Optimal ovarian cancer BNs learned by CausNet and CausNet-partial. حسب Nand Sharma (21519845)

الموضوعات:

Effects of Class Imbalance and Data Scarcity on the Performance of Binary Classification Machine Learning Models Developed Based on ToxCast/Tox21 Assay Data حسب Changhun Kim (682542)

"…In this study, the effects of CI and data scarcity (DS) on the performance of binary classification models were investigated using ToxCast bioassay data. …"

A* Path-Finding Algorithm to Determine Cell Connections حسب Max Weng (22327159)

"…</p><p dir="ltr">Astrocytes were dissociated from E18 mouse cortical tissue, and image data were processed using a Cellpose 2.0 model to mask nuclei. …"

DataSheet1_SS-RNN: A Strengthened Skip Algorithm for Data Classification Based on Recurrent Neural Networks.pdf حسب Wenjie Cao (780652)