Showing 1 - 20 results of 38 for search '(( genes based action optimization algorithm ) OR ( binary based cell optimization algorithm ))', query time: 0.69s Refine Results
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    A* Path-Finding Algorithm to Determine Cell Connections by Max Weng (22327159)

    Published 2025
    “…Pixel paths were classified using a z-score brightness threshold of 1.21, optimized for noise reduction and accuracy. The A* algorithm then evaluated connectivity by minimizing Euclidean distance and heuristic cost between cells. …”
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    Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>" by Doga CEDDEN (12675286)

    Published 2025
    “…</p><p><br></p><p dir="ltr">Chapter 4 introduces the dsRIP web platform (<a href="https://dsrip.uni-goettingen.de/" target="_blank">https://dsrip.uni-goettingen.de/</a>) for designing sequence-optimized dsRNA for RNAi-based pest control. In the experimental part, small interfering RNA (siRNA) features that were associated with RNAi efficacy in human cells were tested in <i>T. castaneum </i>by targeting an essential gene and measuring insecticidal efficacy. …”
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    Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures by Dibyajyoti Das (14845321)

    Published 2023
    “…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …”
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    Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures by Dibyajyoti Das (14845321)

    Published 2023
    “…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …”
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    Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures by Dibyajyoti Das (14845321)

    Published 2023
    “…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …”
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    DataSheet_1_Machine Learning Uses Chemo-Transcriptomic Profiles to Stratify Antimalarial Compounds With Similar Mode of Action.pdf by Ashleigh van Heerden (11041338)

    Published 2021
    “…<p>The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different to current antimalarials. Phenotypic screening has delivered thousands of promising hit compounds without prior knowledge of the compounds’ exact target or MoA. …”
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