Search alternatives:
active optimization » acid optimization (Expand Search), objective optimization (Expand Search), reaction optimization (Expand Search)
whole optimization » whale optimization (Expand Search), wolf optimization (Expand Search), dose optimization (Expand Search)
based active » based practice (Expand Search), based activity (Expand Search)
binary based » library based (Expand Search), linac based (Expand Search), binary mask (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
based whole » used whole (Expand Search)
active optimization » acid optimization (Expand Search), objective optimization (Expand Search), reaction optimization (Expand Search)
whole optimization » whale optimization (Expand Search), wolf optimization (Expand Search), dose optimization (Expand Search)
based active » based practice (Expand Search), based activity (Expand Search)
binary based » library based (Expand Search), linac based (Expand Search), binary mask (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
based whole » used whole (Expand Search)
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Table 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Presentation 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Table 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Image 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Image 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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MultiCRISPR-EGA: Optimizing Guide RNA Array Design for Multiplexed CRISPR Using the Elitist Genetic Algorithm
Published 2025“…Recognizing that more stable gRNAs, characterized by lower minimum free energy (MFE), have prolonged activity and thus higher efficacy, we developed MultiCRISPR-EGA, a graphical user interface (GUI)-based tool that employs the Elitist Genetic Algorithm (EGA) to design optimized single-promoter-driven multiplexed gRNA arrays. …”
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Stochastic simulation and statistical inference platform for visualization and estimation of transcriptional kinetics
Published 2020“…As a demonstration, we show that the optimization algorithm can successfully recover the transcriptional kinetics of simulated and experimental gene expression data. …”
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Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>"
Published 2025“…</p><p><br></p><p dir="ltr">Chapter 4 introduces the dsRIP web platform (<a href="https://dsrip.uni-goettingen.de/" target="_blank">https://dsrip.uni-goettingen.de/</a>) for designing sequence-optimized dsRNA for RNAi-based pest control. In the experimental part, small interfering RNA (siRNA) features that were associated with RNAi efficacy in human cells were tested in <i>T. castaneum </i>by targeting an essential gene and measuring insecticidal efficacy. …”
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<i>hi</i>PRS algorithm process flow.
Published 2023“…The sequences can include from a single SNP-allele pair up to a maximum number of pairs defined by the user (<i>l</i><sub>max</sub>). <b>(C)</b> The whole training data is then scanned, searching for these sequences and deriving a re-encoded dataset where interaction terms are binary features (i.e., 1 if sequence <i>i</i> is observed in <i>j</i>-th patient genotype, 0 otherwise). …”