Showing 1 - 20 results of 56 for search '(( genes based driven optimization algorithm ) OR ( binary data driven optimization algorithm ))', query time: 0.74s Refine Results
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    Table 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf by Valentina Di Salvatore (6296114)

    Published 2025
    “…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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    Presentation 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf by Valentina Di Salvatore (6296114)

    Published 2025
    “…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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    Table 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf by Valentina Di Salvatore (6296114)

    Published 2025
    “…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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    Image 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png by Valentina Di Salvatore (6296114)

    Published 2025
    “…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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    Image 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png by Valentina Di Salvatore (6296114)

    Published 2025
    “…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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    Event-driven data flow processing. by Yixian Wen (12201388)

    Published 2025
    “…Subsequently, we implement an optimal binary tree decision-making algorithm, grounded in dynamic programming, to achieve precise allocation of elastic resources within data streams, significantly bolstering resource utilization. …”
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    MultiCRISPR-EGA: Optimizing Guide RNA Array Design for Multiplexed CRISPR Using the Elitist Genetic Algorithm by Yangyu Zhang (4609117)

    Published 2025
    “…Recognizing that more stable gRNAs, characterized by lower minimum free energy (MFE), have prolonged activity and thus higher efficacy, we developed MultiCRISPR-EGA, a graphical user interface (GUI)-based tool that employs the Elitist Genetic Algorithm (EGA) to design optimized single-promoter-driven multiplexed gRNA arrays. …”
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    Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>" by Doga CEDDEN (12675286)

    Published 2025
    “…The chapter argues that unbiased, screen-based approaches outperform hypothesis-driven gene selection due to the unpredictable influence of cellular processes on RNAi efficacy. …”
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    Flow diagram of the proposed model. by Uğur Ejder (22683228)

    Published 2025
    “…<div><p>Machine learning models are increasingly applied to assisted reproductive technologies (ART), yet most studies rely on conventional algorithms with limited optimization. This proof-of-concept study investigates whether a hybrid Logistic Regression–Artificial Bee Colony (LR–ABC) framework can enhance predictive performance in in vitro fertilization (IVF) outcomes while producing interpretable, hypothesis-driven associations with nutritional and pharmaceutical supplement use. …”
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    Data_Sheet_1_A Data-Driven Framework for Identifying Intensive Care Unit Admissions Colonized With Multidrug-Resistant Organisms.docx by Çaǧlar Çaǧlayan (12253934)

    Published 2022
    “…</p>Materials and Methods<p>Leveraging data from electronic healthcare records and a unique MDRO universal screening program, we developed a data-driven modeling framework to predict MRSA, VRE, and CRE colonization upon intensive care unit (ICU) admission, and identified the associated socio-demographic and clinical factors using logistic regression (LR), random forest (RF), and XGBoost algorithms. …”
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