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based optimization » whale optimization (Expand Search)
work optimization » wolf optimization (Expand Search), swarm optimization (Expand Search), dose optimization (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
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Proposed Algorithm.
Published 2025“…Hence, an Energy-Harvesting Reinforcement Learning-based Offloading Decision Algorithm (EHRL) is proposed. …”
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Comparisons between ADAM and NADAM optimizers.
Published 2025“…Hence, an Energy-Harvesting Reinforcement Learning-based Offloading Decision Algorithm (EHRL) is proposed. …”
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The Pseudo-Code of the IRBMO Algorithm.
Published 2025“…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …”
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IRBMO vs. meta-heuristic algorithms boxplot.
Published 2025“…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …”
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IRBMO vs. feature selection algorithm boxplot.
Published 2025“…In order to comprehensively verify the performance of IRBMO, this paper designs a series of experiments to compare it with nine mainstream binary optimization algorithms. The experiments are based on 12 medical datasets, and the results show that IRBMO achieves optimal overall performance in key metrics such as fitness value, classification accuracy and specificity. …”
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Table 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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Presentation 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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Table 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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Image 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
Published 2025“…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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Image 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
Published 2025“…<p>Recent concerns about off-target immune activation following non-targeted mRNA vaccine delivery have prompted the need for rational design strategies that optimize nanoparticle formulations. Building upon our previous in silico work using the Universal Immune System Simulator to characterize immune responses to mRNA vaccines, we present a computational framework that integrates synthetic transcriptomics with artificial intelligence-driven optimization to guide the development of safer and more targeted lipid nanoparticles. …”
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