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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”
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Towards safe driving: The relation between driving vehicles and drug addiction behaviour
Published 2015“…On the other hand, official statistics in the Kingdom of Saudi Arabia point out to a-ten-fold increase in the previous years in the use of drugs and psychoactive substances.…”
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Autonomous Transaction Model for E-Commerce Management Using Blockchain Technology
Published 2022“…The authors bring it up to design the autonomous transaction system for e-commerce applications; because of the dramatic increase in IoT devices, communication between physical things is enabled. …”
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Evolutionary Game Theory as a Catalyst in Smart Grids: From Theoretical Insights to Practical Strategies
Published 2024“…<p dir="ltr">The increase in the installation of distributed energy resources (DERs) globally has led to a remarkable transformation in the structure of smart grids due to the growing number of energy participants. …”
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Pregnancy and traffic crashes in North America
Published 2015“…The increased risk was largest in the early second trimester and compensated during the third trimester. …”
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Initial risk assessment for pulmonary hypertension in patients with COPD
Published 2012“…Diffusion capacity was lower but did not reach statistical significance (P = 0.07). …”
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Managing Endothelial Dysfunction in COVID-19
Published 2022“…Conclusion Among patients hospitalized with mild, moderate, or severe COVID-19 infection, targeting endothelial dysfunction by administering Nicorandil, L-arginine, Folate, Nebivolol, and Atorvastatin on top of optimal medical therapy did not decrease time to recovery. However, this treatment protocol was associated with an excellent safety profile. …”
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
Published 2002“…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …”
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The impact of water table fluctuation and salinity on LNAPL distribution and geochemical properties in the smear zone under completely anaerobic conditions
Published 2023“…In fluctuating columns, pore water sulfate decreased in the middle, but in stable columns, it decreased in the first 40 days, which suggested that sulfate was the primary electron donor and sulfate-reducing bacteria were present. …”
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Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
Published 2021“…We found that SESN2 silencing, though did not specifically induce ER stress, it aggravated the effects of thapsigargin-induced ER stress on oxidative stress and cell survival. …”
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Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
Published 2024“…Previous reviews suggested potential TXA benefits but did not consider the latest trials. MethodsA systematic review and bias-adjusted meta-analysis were performed to assess TXA’s effectiveness in emergency traumatic injury settings by pooling estimates from randomized controlled trials. …”
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Unsustainability in emergent systems
Published 2017“…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …”
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Parallel Algorithm for Hardware Implementation of Inverse Halftoning
Published 2005Get full text
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Timing driven genetic algorithm for standard-cell placement
Published 1995Get full text
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The challenges of driving licenses in Saudi Arabia
Published 2015“…The Kingdom of Saudi Arabia's booming economy has resulted in the employment of large numbers of immigrants who work as professional drivers in Saudi Arabia, who come from different cultural and social environments which contributes to an increase in the human factor as the major cause of traffic crashes. …”