Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... حسب Alize J, Ferrari

"…However, despite this overall increase, HALE decreased by 2·2% (1·6–2·9) between 2019 and 2021. …"
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Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors حسب Zeyaul Islam (5867387)

"…Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, also binds to Sox9 and results in a similar increase in pancreatic development markers. …"

Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy حسب Chaoul, Victoria

"…Early upregulation of Epac1 transcripts was noted in diabetic hearts at Week 4, followed by increases in Epac2 mRNA, but not protein levels, at Week 12. …"
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In-situ grown ternary metal hydroxides@3D oriented crumpled V₂C MXene sheets for improved electrocatalytic oxygen evolution reaction حسب Iqbal, Anum

"…In essence, this study features a facile approach for the confined growth of multi transition metal hydroxides in the presence of morphologically unique 3D crumpled V₂C MXene architectures. Consequently, the increased OER reaction kinetics and improved stability of the synthesized composites are potentially due to synergistic interplay between well dispersed active sites and the conductive substrate.…"
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Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women حسب Manjunath Ramanjaneya (519259)

"…Higher numbers of top-quality embryos were associated with increased levels of C3, properdin, C1q, factors H and B, C4, and adipsin, but with reduced C2 and C5a levels (p ≤ 0.01).…"

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country حسب Nancy Zaghloul (14147865)

"…The trend among SGLT2is suggests greater preference for empagliflozin over dapagliflozin.…"

Coevolving residues distant from the ligand binding site are involved in GAF domain function حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Ligand binding to GAF domains regulates the activity of associated catalytic domains in various proteins, such as the cGMP-hydrolyzing catalytic domain of phosphodiesterase 5 (PDE5) activated by cGMP binding to GAFa domain. …"

Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv... حسب Abdoulaye Diane (14152749)

"…This consists of 6 stages: S1, definitive endoderm; S2, gut tube endoderm; S3, pancreatic progenitors 1; S4, pancreatic progenitors 2; S5, endocrine precursors; and S6, β-like cells. …"

OSRA Grant Cycle 5 Public Reports : Project Title: Comprehensive Parenting Program to Enhance Preterm Infants’ Health and Development A Randomized Controlled Trial حسب Lama Charafeddine (6843536)

Lifetime prevalence, risk, and treatment of mood and anxiety disorders in Qatar's national mental health study حسب Salma Mawfek Khaled (14159013)

"…Treatment contact in the year of disorder onset were 13.5%. The median delay in receiving treatment was 5 years (IQR = 2–13). …"

Theoretical and experimental investigations of vanadium pentoxide–based electrocatalysts for the hydrogen evolution reaction in alkaline media حسب Dima Abu Alhawa (21768260)

"…This was reflected experimentally through kinetically non-ideal alkaline electrochemical HER using Zn_0.4V_1.6O₅ whereby − 194 mV of overpotential was required to attain − 10 mA/cm² of current density, as opposed to pristine V₂O₅ which required 32% higher overpotential requirement at the same conditions. …"

Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation حسب Salman, Zeina

"…Western blot and pathway analyses demonstrated that miR-222-5p and miR-21-3p overexpression increased phosphorylation of p65, a key component of the NF-κB complex, while their knockdown reduced p65 phosphorylation. …"
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…These results reiterate the decisive role of 5-Aza-CdR in lung cancer treatment since it induces the epigenetic regulation of NY-ESO-1 antigen, inhibits cell proliferation, increases apoptosis, and decreases invasiveness.…"

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort حسب Muneerah Smith (12542939)

"…As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. A significant increase in antibody titer and epitope coverage was observed with increasing age, in both mild and severe disease, which is promising for vaccine efficacy in older individuals. …"

Role of Active Morphing in the Aerodynamic Performance of Flapping Wings in Formation Flight حسب Billingsley, Ethan

"…Migratory birds have the ability to save energy during flight by arranging themselves in a V-formation. This arrangement enables an increase in the overall efficiency of the group because the wake vortices shed by each of the birds provide additional lift and thrust to every member. …"
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Review on COVID-19 diagnosis models based on machine learning and deep learning approaches حسب Abu Zitar, Raed

"…The exponential increase in the number of infections has rendered traditional diagnosis techniques inefficient. …"
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OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... حسب Pia Tohme Khalaf (17425551)

Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study حسب Husham Abdelrahman (768893)

"…The female/male ratio was 17.5%/82.5%, and the mean injury severity score was 13 ± 9. …"

The Identification Process & Tools for Gifted and Talented Students: Research on Five inclusive government schools in Ajman to study the areas of identification process tools utili... حسب Hersi, Maryam Salem Mohammed Saed

"…With the increase focus on innovation and creativity, the Giftedness Education has become embedded with the UAE government’s future strategies. …"
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