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Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling
Published 2019“…Background: The expression of connexin 43 (Cx43) is disrupted in breast cancer, and re-expression of this protein in human breast cancer cell lines leads to decreased proliferation and invasiveness, suggesting a tumor suppressive role. …”
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302
Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters
Published 2021“…., intercept, slope and average residual between sample and reference lines) by integrating them with run rules in order to quickly detect various magnitudes of shifts in profile parameters. …”
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Phase transitions of nanoemulsions using ultrasound: Experimental observations
Published 2012“…Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions.…”
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305
Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
Published 2024“…The methodological quality of the trials underwent assessment using the MASTER scale, and the meta-analysis applied the quality-effects method to adjust for methodological quality. …”
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306
Economics of hydrogen production and liquefaction by geothermal energy
Published 2012“…Also, capital costs for the models involving hydrogen liquefaction are greater than those for the models involving hydrogen production only.…”
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307
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…We find that monthly shrinkage rates have a pronounced structured variability around the channel network with the shrinkage rate systematically decreasing farther away from the channels. This pattern of shrinkage is predominantly attributed to a deeper active layer enhancing near-surface connectivity and storage and greater vegetation density closer to the channels leading to increased evapotranspiration rates. …”
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Role of nutritional indices in predicting outcomes of vascular surgery
Published 2019“…Background Malnutrition is frequent among vascular surgery patients, given their age, chronic comorbidities, and poor functional status, and it is believed to increase their operative risk. …”
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310
Giving fragile bones a stronger foothold
Published 2016“…In the West, diagnosis, treatment and research of the condition, which causes bones to become fragile, have increased. But less attention is given to it in the Middle East and Africa, with only a few countries in both regions providing accessible guidelines for its prevention and treatment. …”
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Diet-induced mechanical stress promotes immune and metabolic alterations in the<i> Drosophila melanogaster </i>digestive tract
Published 2025“…Particularly, we show that feeding on MC-containing diet promotes a marked increase in the relative abundance of Leuconostocaceae/Leuconostoc, microbiota-dependent Reactive Oxygen Species (ROS) production, IMD pathway activation, and IMD-dependent elevation in <i>Tk</i> expression. …”
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Use of a two-parameter Weibull distribution for the description of the particle size effect on dust minimum explosible concentration
Published 2024“…The results show that as the scale and shape parameters increase, the MEC increases with higher dependence on the scale parameter (<i>b</i>). …”
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The Assessment of Wind Power for Electricity Generation in Lebanon
Published 2010“…Implementing such wind farms would greatly decrease the harmful emission of greenhouse gases produced by the energy sector devoted to electricity generation by fuel (El-Fadel et al., 2003). …”
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314
Social impact projections for Qatar youth residents from 2022: The case of the IAAF 2019
Published 2022“…The study is of significance within the context of residents' perceptions studies given that the large majority of residents in Qatar are non-Qataris. …”
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315
CEO gender and managerial entrenchment
Published 2020“…We find that the presence of female CEO decreases the turnover-performance sensitivity, increases the E-index, and inflates CEO compensation. …”
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316
Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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317
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
Published 2008“…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …”
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318
PSA-activated proaerolysin as a prostate specific cancer therapy
Published 2006“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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HVAC system attack detection dataset
Published 2021“…<p dir="ltr">The importance of the security of building management systems (BMSs) has increased given the advances in the technologies used. …”
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Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis
Published 2021“…A convenience sample was recruited in 4 GPs in West Yorkshire, England. Given that the quantitative data were analyzed in a previous study, we analyzed the qualitative data using thematic analysis.…”