-
521
Lipid profile in Parkinson's disease: The potential role of brain-derived neurotrophic factor
منشور في 2022"…<h3>Background</h3><p dir="ltr">Parkinson's disease is a neurodegenerative disease manifested as increased tremor, bradykinesia, rigidity, and postural instability. …"
-
522
A novel design for battery cooling based on highly thermally conductive phase change composites encapsulated by 3D printed polyethylene/boron nitride layer
منشور في 2025"…However, their susceptibility to self-heating impacts their performance, service life, and safety. Thus, efficient thermal management devices are indispensable. …"
-
523
A novel IoT intrusion detection framework using Decisive Red Fox optimization and descriptive back propagated radial basis function models
منشور في 2024"…<p dir="ltr">The Internet of Things (IoT) is extensively used in modern-day life, such as in smart homes, intelligent transportation, etc. …"
-
524
Prediction of Multiple Clinical Complications in Cancer Patients to Ensure Hospital Preparedness and Improved Cancer Care
منشور في 2022"…Myelosuppression due to treatment increases the risk of sepsis and mortality in hematological cancer patients with febrile neutropenia. …"
-
525
Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity
منشور في 2024"…Thus, identifying the pathway involved in this toxicity may help minimize chemotherapy risk and improve cancer patients’ quality of life. Recent studies suggest that Endothelial-to-Mesenchymal transition (EndMT) and endothelial toxicity contribute to the pathogenesis of DOX-induced cardiovascular toxicity. …"
-
526
The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects
منشور في 2022"…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …"
-
527
Challenges and opportunities in biogas conversion to microbial protein: A pathway for sustainable resource recovery from organic waste
منشور في 2024"…Concurrently, urban expansion significantly increases organic waste, undermining both economic and environmental sustainability. …"
-
528
Extent and Mitigation of Financial Toxicity of Immune Checkpoint Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma
منشور في 2025"…We also aim to explore potential solutions to improve access to life-saving therapies such as ICIs. We conducted an exploratory targeted review of the current literature focusing on therapeutic advancements, their accessibility, and innovative strategies to overcome FT. …"
-
529
Building thermal resilience framework (BTRF): A novel framework to address the challenge of extreme thermal events, arising from climate change
منشور في 2022"…Moreover, recently, the rate and the impacts of these extremes have increased, despite all the mitigation efforts, necessitating a resilience-based approach to address these challenges stemming from the accelerated global warming and the advent of climate change. …"
-
530
Developing a Framework for Evaluating Accessibility Density and Coverage
منشور في 2015احصل على النص الكامل
doctoralThesis -
531
-
532
The Integration of Agile Methodology in the Development of Software Project
منشور في 2024"…Agile proponents have produced a number of assertions regarding the advantages of agile approaches, such as increased group productivity and effectiveness, improved software reliability, and business effectiveness. …"
احصل على النص الكامل
-
533
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
منشور في 2021"…</p><p><br></p><h3>Interpretation</h3><p dir="ltr">In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. …"
-
534
Phase 1 and 2 Studies Demonstrate the Safety and Efficacy of Intraprostatic Injection of PRX302 for the Targeted Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prost...
منشور في 2011"…Phase 1 subjects received increasing concentrations of PRX302 at a fixed volume; phase 2 subjects received increasing volumes per deposit at a fixed concentration. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
535
Prostate cancer burden in South Asia: A systematic analysis of global burden of disease data (1990–2021)
منشور في 2024"…<h3>Objectives</h3><p dir="ltr">The objectives of this study were to analyze trends in prostate cancer incidence, incidence, mortality, and disability‐adjusted life years (DALYs) from 1990 to 2021 via data from the Global Burden of Disease (GBD) study in South Asia. …"
-
536
Incidence, risk factors and outcomes of nosocomial infection in adult patients supported by extracorporeal membrane oxygenation: a systematic review and meta-analysis
منشور في 2024"…<h3>Background</h3><p dir="ltr">An increasing number of patients requires extracorporeal membrane oxygenation (ECMO) for life support. …"
-
537
Ervilia castanea (Mollusca, Bivalvia) populations adversely affected at CO2 seeps in the North Atlantic
منشور في 2021"…This raises concerns about the effects of ocean acidification on the brood stock of this species and other bivalve molluscs with similar life history traits.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
538
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making
منشور في 2019"…This study aims to investigate the Saudi public’s attitude toward FIH clinical trials, identify their willingness to take part in it, and their preferences for participating in these kinds of trials, given the fact that the Saudi FDA has never approved such studies in Saudi Arabia. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
539
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
منشور في 2022"…<p>Loss of function mutations in store-operated Ca<sup>2+</sup> entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …"
-
540
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…<p dir="ltr">Transport of fine particles in porous media has attracted a considerable interest over the past several decades given its importance to many industrial and natural processes. …"