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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Work-life balance, perceived stress, & locus of control
منشور في 2014"…According to the result of this study, work life balance is positively affected by an increased level of control as well as a decreased level of perceived stress. …"
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Effect of UV Ageing on the fatigue life of bulk polyethylene
منشور في 2018"…Although few studied investigated the effect of UV irradiation on the mechanical behaviour of thermoplastics, fewer examined the UV irradiation effect on the fatigue life of polymers. This study focuses on investigating the effect of UV irradiation on the fatigue properties of bulk semi-crystalline polymer; the low density Polyethylene (LDPE). …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019
منشور في 2021"…Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. …"
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Early‐Life Sugar Consumption Affects the Microbiome in Juvenile Mice
منشور في 2023"…<i>Firmicutes</i> population are gradually increased in treated samples even after the recovery period, whereas <i>Bacteroidetes</i> abundance slightly reduces throughout the study.…"
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
منشور في 2024"…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …"
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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
منشور في 2020"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. This positive correlation between sperm rDNA methylation and biological age is evolutionarily conserved among mammals with widely different life spans such as humans, marmoset, bovine, and mouse. …"
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Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 20...
منشور في 2024"…Under our Elimination-2023 scenario, we forecast 2·04 billion (95% UI 1·90–2·21) fewer cumulative YLLs by 2050 compared with the reference scenario, and life expectancy at birth would increase to 77·6 years (95% UI 75·1–79·6) among males and 81·0 years (78·5–83·1) among females. …"
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The Effects of New Public Management on Managers’ Work-Life Balance and Behavior
منشور في 2020"…In addition, the participants maintained positive attitudes to the increase in job responsibility, often stating that an increased scope of work was a natural phenomenon that came with the job. …"
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Study of Life Cycle Cost Analysis and Value Engineering and their use in UAE
منشور في 2021"…Results show that investing more money in the initial phase, mainly the construction phase, to improve the materials and construction quality would increase the service life by up to 20 years. which will result in more profit to the owners/stakeholders taking into consideration safety requirements.…"
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Impact of Plant Life on Formaldehyde Levels in an Existing Office Setting In the UAE
منشور في 2015"…The toxin formaldehyde has been associated with muscle weakness, itchy eyes/ skin and is considered a carcinogen. Plant life has been long associated with cleaning air and improving IAQ levels. …"
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