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321
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
Published 2013“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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322
Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
Published 2023“…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. In line with IOM recommendations, we found that higher BMI was correlated with decreased GWG and BMI was significantly associated with GWG even after adjusting for maternal age, parity, and infants’ gestational age at birth. …”
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323
CORROSION OF FUSION-BONDED EPOXY COATED BARS IN CHLORIDE-CONTAMINATED PLAIN AND SiLICA FUME CEMENT CONCRETES EXPOSED TO VARYING TEMPERATURE
Published 2020“…The corrosion current density on mild steel and damaged FBEC bars was noted to increase with an increase in temperature. The performance of FBEC bars in the silica fume cement concrete was better than that in the plain cement concrete at both normal and elevated temperatures. …”
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324
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
Published 2024“…<h3>Introduction</h3><p dir="ltr">The unprecedented impact of the coronavirus pandemic (COVID-19) has had profound implications on the ASD community, including disrupting daily life, increasing stress and emotional dysregulation in autistic children, and worsening individual and family well-being.…”
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325
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
Published 2021“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”
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327
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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328
Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment
Published 2022“…The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …”
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329
The Effects of Online Formative and Summative Assessment on Test Anxiety and Performance: A Study Among First-Year Undergraduate Students at A Higher Education Institution in Abu D...
Published 2019“…The presented study was conducted to provide greater insight into the potential positive, neutral and/or negative effects of online formative and summative assessment on test anxiety and performance. …”
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330
Notes total mesorectal excision (TME) for patients with rectal neoplasia
Published 2014“…This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. …”
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331
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca<sup>2+</sup> entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”
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332
The relation between motivational and behavioral cultural intelligence and the three dimensions of cross-cultural adjustment among Arabs working in the USA
Published 2010“…For a number of years the number of businesses going internationally has increased. With the increase of international businesses, an increase of cross-cultural interaction at the different levels and aspects of our life around the world took place. …”
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333
Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
Published 2015“…Several well-designed randomized trials confirmed that the synergistic effect of both drugs in combination was able to improve lung function and health-related quality of life without a significant increase in adverse effects. …”
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334
Strain response of hot-mix asphalt overlays for bottom-up reflective cracking
Published 2017“…Moreover, the rate of horizontal strain accumulation increases with higher overlay thickness. Although initial strain values were higher at positive pavement temperature distributions, the corresponding rate of strain increase were higher at negative pavement temperatures. …”
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335
Digital wellbeing tools through users lens
Published 2021“…One strategy to help regulate digital usage and, potentially, increase digital wellbeing is to devise smartphone applications to collect data about usage and increase users' awareness of it and enable them to set limits and alert users accordingly. …”
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336
Home Automation Awareness in United Arab Emirates
Published 2018“…Mega IT companies are investing into researches to combine IoT, Artificial Intelligence, and automation to increase the efficiency and productivity of things around us hoping to make people’s life more convenient. …”
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337
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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338
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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339
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
Published 2014“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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340
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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