Enhanced generation of beta cell precursors and functional insulin-secreting cells from human pluripotent stem cells by Bushra Memon (4792767)

“…The transcriptome profile of PDX1−/NKX6.1+-derived beta cells was closely like those of human pancreatic islets and purified hPSC-derived beta cells.…”

Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12 by Kripa S Keyan (10644815)

“…Instead, <i>TRIP12</i> recruits SMURF2 to SMAD4, which is most likely responsible for inhibitory monoubiquitination of SMAD4, since SMAD4 monoubiquitination and its interaction with SMURF2 were dramatically downregulated in <i>TRIP12</i>^<em>-</em>^/- cells. …”

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis by Alaa Abd-Alrazaq (17430900)

“…There are practical considerations that, if incorporated into the system, are likely to improve its adoption rate: Patient Online should be useful, easy to use, secure, and easy to access. …”

The Study of Maternal Factors and Their Association with Risk of Preterm Birth by Alaa Al-Naama (17075063)

“…We hypothesize that certain maternal factors increase the risk of PTBs.</p> <h3>Design</h3> <p>A retrospective study recruiting women in labor at WWRC from June 2022 until February 2023.…”

Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study by Tamara Al-Abdi (8710488)

“…Openness was positively associated with all PA (<i>p </i>= 0.027), including walking (<i>p </i> = 0.026), and negatively associated with sitting (<i>p </i> = 0.038) before lockdown, while participants with high scores for neuroticism were less likely to be sitting during lockdown (<i>p </i> = 0.042). …”

Computed tomography-detected hemothorax after blunt chest trauma: Does everyone need an intervention? A retrospective analysis by Ismail Mahmood (14150352)

“…Patients with larger hemothorax volumes were significantly more likely to require tube thoracostomy (<i>p</i> = 0.001) and had significantly longer hospital stays (<i>p</i> = 0.021). …”

Investigating the incidence, nature, severity and potential causality of medication errors in hospital settings in Qatar by Binny Thomas (5801969)

“…Effort is required to increase the effectiveness and efficiency of the reporting system. …”

Hurdling the Challenges of the 2019 IAAF World Championships by Olivier Girard (409080)

“…In particular, athletes are likely to encounter challenging hot temperatures and potentially high humidity levels that may eventually impair performance during middle and long distance events and increase the risk of exertional heat. …”

A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater by Azar, Riad

“…We anticipate that the debate on the roles of surgery and endoscopy in the treatment of small cancerous tumors will likely increase as experience with endoscopic resection increases. …”
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RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …”

Road deaths and injuries in India: Action required on the five pillars of road safety by Gopalakrishna Gururaj (19807233)

“…While urban deaths account for nearly a fifth of total deaths and injuries, Indian highways account for more than 50% of deaths and injuries and are likely to increase with further growth in infrastructure (1). …”

Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study by Mona Abdi (10196665)

“…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …”

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…The author’s line of argument is that conceptual skills are likely to play a significant role in ambidexterity leadership for innovation. …”
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study by Rajesh, Sharma

“…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …”
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Holistic Transitional Approach of Humanitarian Shelters Through The Implementation of Adaptable Design Strategies. by ALSHALABI, WASEEM

“…The issue of forcibly displaced portions of a population has become an emerging global trend that is driven by significantly increased numbers of displaced people. This is caused by increases in natural disasters due to global warming, war, and other conflicts. …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…The share of livebirths was projected to decline between 2021 and 2100 in most of the six other super-regions—decreasing, for example, in south Asia from 24·8% (23·7–25·8) in 2021 to 16·7% (14·3–19·1) in 2050 and 7·1% (4·4–10·1) in 2100—but was forecast to increase modestly in the north Africa and Middle East and high-income super-regions. …”
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New media and new practices of exploitation by Uzunoglu, Sarphan

“…Today, in new media sphere, tracking technologies replaced rating systems and data about consumer is being sold. Increasing use of new media and increasing Internet penetration through rising sales numbers of mobile devices caused a necessity for a new debate. …”
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Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 by Marie, Ng

“…Assuming the continuation of historical trends, by 2050, we forecast that the total number of adults living with overweight and obesity will reach 3·80 billion (95% UI 3·39–4·04), over half of the likely global adult population at that time. While China, India, and the USA will continue to constitute a large proportion of the global population with overweight and obesity, the number in the sub-Saharan Africa super-region is forecasted to increase by 254·8% (234·4–269·5). …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... by Robert C Reiner (5147636)

“…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …”