Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…We have established that autophagy, a process of cellular destruction activated in response to arginine deprivation, can be the leading cause of cell death at late drug incubation times. Hence, our study demonstrates that HuArgI (Co)-PEG5000 is a novel, potent and selective potential therapeutic approach for PC.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …"

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers حسب Farhat Abbas (5480)

"…Column Peclet numbers from the two analyses were identical for potassium ions but those for bromide ions were c. 60% greater from the two-region model than from the convective–diffusion equation. …"

Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration حسب Milane, Aline

"…Inflammation and Parkinson’s-like lesions induced by MPTP intoxication could lead to modification of drug pharmacokinetics and have clinical consequences, such as neurotoxicity.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Proliferation and differentiation of human adipose-derived mesenchymal stem cells (ASCs) into osteoblastic lineage are passage dependent حسب Faour, Wissam

"…Morphologically, cells in various subcultivation stages showed flattened shape at low density but spindle-like structures at confluency as judged by phalloidin staining. …"
احصل على النص الكامل
احصل على النص الكامل

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions حسب Murali K. Akula (9389280)

"…Non-prenylated Rac1 has a high affinity for the adaptor protein Ras GTPase-activating-like protein 1 (Iqgap1), which facilitates both GTP exchange and ubiquitination-mediated degradation of Rac1. …"

Editorial: Special Issue - Economics in Digital Construction حسب Georgios Kapogiannis (16654971)

"…The rapid adoption of technologies like Building Information Modelling (BIM) and digital asset management systems has set a new paradigm in project efficiency and data utilisation. …"

RETRACTED_Impact of Activation, Optimization, and Regularization Methods on the Facial Expression Model Using CNN حسب Irfan Ali Kandhro (17541876)

"…Recently published studies have found that deep learning is becoming increasingly popular in the field of image categorization. …"

A study on Speaker Recognition System حسب Bakkar, Hazem Wa'il Mohammed

"…"The huge development in information technology opened the door for finding an increasing number of security gaps in the daily used systems like email accounts. …"
احصل على النص الكامل

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... حسب Parkes J Kendrick (9714851)

"…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …"

Supplementation of retrobulbar block with clonidine in vitreoretinal surgery حسب Abi Nader, Elie

"…Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Foreign currency borrowing by small firms in emerging markets حسب Mora, Nada

"…Bank relationships, however, do not increase the dollar debt likelihood. And finally, profitable firms are less likely to have dollar debt. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Influence of co-current vapor flow on falling film over horizontal tube حسب Furqan Tahir (14429547)

"…First, the liquid load is varied between 0.02 and 0.05 kg/(m·s), and its effects on the film thickness and the wetting time are calculated, presented and discussed. Afterwards, the impact of co-current vapor flow on film distribution, wetting time, minimum thickness and its location are quantified and examined by increasing the vapor velocity up to 6 m/s with 2 m/s intervals. …"

Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics حسب Farah F. Salameh (21797300)

"…The impact of various parameters on MB removal was assessed, including solution pH, adsorbent dosage, pollutant concentration, and contact time. Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …"

Self-Organization and Multi-Agent Reinforcement Learning for Taxi Dispatch حسب Alshamsi Omran, Aamena Ali Ahmed

احصل على النص الكامل

Viability of Amazon’s driven innovations targeting shoppers’ impulsiveness حسب Farah, Maya F.

"…Such tech-disruptions are likely to have a significant bearing on shoppers, brands and retailers, which is expected to vary between the short and the long-term. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Board composition, CEO turnover and firm value حسب Dah, Mustafa A.

"…The results suggest an increase in the participation of independent directors at the expense of insiders. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Harnessing plastic waste for sustainable membrane filtration with trimodal structure through acid-catalyzed oxidation حسب Saleem, Junaid

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study حسب Qamar, Adnan

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Assessment of ferrous chloride and Portland cement for the remediation of chromite ore processing residue حسب Wazne, Mahmoud

"…The remediation of COPR has been challenging due to the slow release of Cr(VI) from a clinker like material and thereby the incomplete detoxification of Cr(VI) by chemical reagents. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل